PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Kalax.0408s0036.1.p
Organism
Kalanchoe marnieriana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe
Family HD-ZIP
Protein Properties Length: 716aa    MW: 78819.6 Da    PI: 6.9329
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Kalax.0408s0036.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox64.41.6e-202378156
                         TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
             Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                         +++ +++t++q+++Lee+F+++++p+ ++r++L++ l+L  rq+k+WFqNrR++ k
  Kalax.0408s0036.1.p 23 KKHYHRHTAHQIQRLEEAFKECPHPDDKQRQQLSRDLKLAPRQIKFWFQNRRTQLK 78
                         688999**********************************************9877 PP
2START152.73.1e-482244472206
                          HHHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....E CS
                START   2 laeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv.....dsgealrasgvvdmvlallveellddkeqWdetla....k 78 
                          +a  aa+e+ ++ + +ep+Wvks+    + +n d + + f ++++     +++e +r+sgvv m++  lv  +++++  W e ++     
  Kalax.0408s0036.1.p 224 IAANAAEEVHRLLQTDEPLWVKSAtdgrQVLNLDMYHKMFRRANNhmnpnSRVESSRDSGVVLMNSIALVGMFMNSN-TWMELFPtivsT 312
                          577899999*****************9999999999999999888999*****************************.99999999998* PP

                          EEEEEEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCE CS
                START  79 aetlevissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksngh 161
                          a t++v+s+g      gal+lm ae q+lsplvp R+f f+Ry++q ++g w+i+dvS d + + +  ss   +++lpSg+li++ +ng 
  Kalax.0408s0036.1.p 313 ARTIQVLSPGllgnqnGALHLMHAEVQVLSPLVPtREFFFLRYCQQVQQGLWIIADVSCDFPCNHQ-FSSRHLSHRLPSGCLIQDIPNGF 401
                          **************************************************************9998.6788889**************** PP

                          EEEEEEE-EE--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
                START 162 skvtwvehvdlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                          skv+wve+v+ ++r+p h l+  l++sg a+ga +w atlqr ce+
  Kalax.0408s0036.1.p 402 SKVIWVERVEIQDRSPpHLLYTDLISSGFAFGAERWIATLQRVCER 447
                          ****************9***************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.601.7E-201180IPR009057Homeodomain-like
SuperFamilySSF466893.51E-181682IPR009057Homeodomain-like
PROSITE profilePS5007117.0382080IPR001356Homeobox domain
SMARTSM003898.9E-182284IPR001356Homeobox domain
CDDcd000863.20E-182380No hitNo description
PfamPF000464.6E-182378IPR001356Homeobox domain
PROSITE patternPS0002705578IPR017970Homeobox, conserved site
PROSITE profilePS5084845.015214450IPR002913START domain
SuperFamilySSF559612.06E-30217448No hitNo description
CDDcd088753.11E-102218446No hitNo description
SMARTSM002343.5E-42223447IPR002913START domain
PfamPF018526.3E-41224447IPR002913START domain
Gene3DG3DSA:3.30.530.201.9E-6305417IPR023393START-like domain
SuperFamilySSF559613.85E-18466701No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 716 aa     Download sequence    Send to blast
MEDFGLGGPE QAADPNQEEK MKKKHYHRHT AHQIQRLEEA FKECPHPDDK QRQQLSRDLK  60
LAPRQIKFWF QNRRTQLKGQ LERADNCVLR AENDKIRCEN IAMREALRNI ICPNCGAPPD  120
LQEDSFFDER KLRLDNAQLK EELDRVSSIA ANYIGRPVTQ LPPVQPINIS SLDLSMGSFG  180
GKGMHGPSLN LDLPAGATSS ALNNLQLQPV LALSDTQKSI MTTIAANAAE EVHRLLQTDE  240
PLWVKSATDG RQVLNLDMYH KMFRRANNHM NPNSRVESSR DSGVVLMNSI ALVGMFMNSN  300
TWMELFPTIV STARTIQVLS PGLLGNQNGA LHLMHAEVQV LSPLVPTREF FFLRYCQQVQ  360
QGLWIIADVS CDFPCNHQFS SRHLSHRLPS GCLIQDIPNG FSKVIWVERV EIQDRSPPHL  420
LYTDLISSGF AFGAERWIAT LQRVCERFSF FLDTLTREPG GANLIPDGKK SMMKLGQRMI  480
TNFCATVSTA NAHPCTTVAG FSESGIRVTV RKSTTAGNPS SDVVLSAATT IWLPVSPQTI  540
FDFFKDEQKR AQWDVLSRGN PIQEMAHISN GSHPGNCISV LQACDSHQGN VVILQETSVD  600
ASGSLLVFCP VELPSIQATM SGQDPSCIPL FPSGFTISPD GRPGEAGTSS SSSHGAMSRS  660
SGSLVTVAFQ ILVSSLPSSK LTSESANTVT NLITTTVRYI KAALNCPETL EAESV*
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017973835.10.0PREDICTED: homeobox-leucine zipper protein HDG11
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A2N9ELU80.0A0A2N9ELU8_FAGSY; Uncharacterized protein
STRINGXP_010099679.10.0(Morus notabilis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]