PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe

Family

HSF

Protein Properties

Length: 297aa MW: 32742.8 Da PI: 5.8995

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Kalax.0160s0044.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	114.5	6.9e-36	10	100	2	101
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkk 91 Fl+k++++++d+++++++swse+g++fvv+++ efak++LpkyFkh+nf+SFvRQLn+YgF+k+ ++ weF++++Fkkg+ Kalax.0160s0044.1.p 10 FLTKTFQLVDDRSTDDVVSWSEDGSTFVVWKTAEFAKDLLPKYFKHNNFSSFVRQLNTYGFRKTVPDK---------WEFANEHFKKGQA 90 9*************************************************************9999.........********* PP XXXXXXXXXX CS HSF_DNA-bind 92 ellekikrkk 101 ell++i+r+k Kalax.0160s0044.1.p 91 ELLTEIRRRK 100 ******98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.7E-37	4	93	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	2.0E-59	6	99	IPR000232	Heat shock factor (HSF)-type, DNA-binding
SuperFamily	SSF46785	1.18E-33	6	99	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF00447	1.0E-31	10	99	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.0E-20	10	33	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.0E-20	48	60	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.0E-20	61	73	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 297 aa Download sequence Send to blast
MTVRSAPAPF LTKTFQLVDD RSTDDVVSWS EDGSTFVVWK TAEFAKDLLP KYFKHNNFSS 60 FVRQLNTYGF RKTVPDKWEF ANEHFKKGQA ELLTEIRRRK AVIASQAAGK ATGGGSSPSN 120 SVEDLGSTST SSPGSADEIV MQLTGLSDEN EKLKKDNVKL NSELVRTKKQ CEELVGFVAR 180 YMKVGVEEID GIMKQQGAAL SSSSQPKTIV AIRDDDENEE AVGGEEEEEK VKVDSLKLFG 240 VWLKGEKGTK NKRCRDEAAL PHSDNPITNG DSSGNKKMKN VEFDASWMKM STVVPQ*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	4e-25	5	99	25	129	Heat shock factor protein 1
5d5v_B	4e-25	5	99	25	129	Heat shock factor protein 1
5d5v_D	4e-25	5	99	25	129	Heat shock factor protein 1
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Functional Description ? help Back to Top
Source	Description
UniProt	DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002277765.2	1e-101	PREDICTED: heat shock factor protein HSF24
Swissprot	P22335	6e-96	HSF24_SOLPE; Heat shock factor protein HSF24
TrEMBL	A0A438KJJ4	1e-99	A0A438KJJ4_VITVI; Heat shock factor protein HSF24
TrEMBL	D7SVY0	1e-99	D7SVY0_VITVI; Uncharacterized protein
STRING	VIT_07s0031g00670.t01	1e-100	(Vitis vinifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36990.1	1e-83	heat shock factor 4

Link Out ? help Back to Top
Phytozome	Kalax.0160s0044.1.p

Publications ? help Back to Top
Scharf KD, et al. Three tomato genes code for heat stress transcription factors with a region of remarkable homology to the DNA-binding domain of the yeast HSF. EMBO J., 1990. 9(13): p. 4495-501 [PMID:2148291]