PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe

Family

WRKY

Protein Properties

Length: 292aa MW: 32499.6 Da PI: 7.0103

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Kalax.0083s0051.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	100.6	9.4e-32	214	272	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 ldDgy+WrKYGqK+vk+s +prsYYrCt+ gC+vkk+ver +ed ++v++tYeg+H h+ Kalax.0083s0051.1.p 214 LDDGYKWRKYGQKVVKNSLHPRSYYRCTQMGCRVKKRVERLSEDCRMVITTYEGRHSHP 272 59********************************************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	8.1E-34	199	274	IPR003657	WRKY domain
SuperFamily	SSF118290	4.84E-29	206	274	IPR003657	WRKY domain
PROSITE profile	PS50811	31.514	209	274	IPR003657	WRKY domain
SMART	SM00774	2.5E-37	214	273	IPR003657	WRKY domain
Pfam	PF03106	9.2E-25	215	272	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 292 aa Download sequence Send to blast
MEGGGGGREF VFGSRDDDHQ GSIFSTHPRQ MELHHNSDDF LAASSSSAPA AANNRHVFTL 60 LSHHPNSSST STPATACVAA AGGSTMAMGF INCHNEEEEK DDDQHLFAAH DNRLLNAWKT 120 VYHQQHGLRS TILDPREADG VGNNEEDYHG DDTQTTENSH SWWRRCPASS SSEKITSKAA 180 SGKISGSSTG VVKMRRKLRE PRFCFQTRTD IDVLDDGYKW RKYGQKVVKN SLHPRSYYRC 240 TQMGCRVKKR VERLSEDCRM VITTYEGRHS HPPPPPDDAN SSDHDPCFSS F*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	3e-25	205	274	8	77	Probable WRKY transcription factor 4
2lex_A	3e-25	205	274	8	77	Probable WRKY transcription factor 4
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00618	PBM	Transfer from AT2G44745	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017604132.1	3e-59	PREDICTED: probable WRKY transcription factor 12
Swissprot	Q93WY4	4e-57	WRK12_ARATH; Probable WRKY transcription factor 12
TrEMBL	A0A151QW85	2e-57	A0A151QW85_CAJCA; Putative WRKY transcription factor 12
STRING	Gorai.004G069500.1	3e-57	(Gossypium raimondii)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G44745.1	7e-50	WRKY family protein

Link Out ? help Back to Top
Phytozome	Kalax.0083s0051.1.p

Publications ? help Back to Top
Yu Y, et al. MlWRKY12, a novel Miscanthus transcription factor, participates in pith secondary cell wall formation and promotes flowering. Plant Sci., 2013. 212: p. 1-9 [PMID:24094048] Yang L, et al. PtrWRKY19, a novel WRKY transcription factor, contributes to the regulation of pith secondary wall formation in Populus trichocarpa. Sci Rep, 2016. 6: p. 18643 [PMID:26819184] Li W,Wang H,Yu D Arabidopsis WRKY Transcription Factors WRKY12 and WRKY13 Oppositely Regulate Flowering under Short-Day Conditions. Mol Plant, 2016. 9(11): p. 1492-1503 [PMID:27592586] Han Y, et al. WRKY12 represses GSH1 expression to negatively regulate cadmium tolerance in Arabidopsis. Plant Mol. Biol., 2019. 99(1-2): p. 149-159 [PMID:30617455]