PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe

Family

ARR-B

Protein Properties

Length: 677aa MW: 73445.6 Da PI: 6.7141

Description

ARR-B family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Kalax.0011s0116.2.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	G2-like	91.7	6.1e-29	218	271	1	55
G2-like 1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 kpr++W+ eLH++Fv+av+qL G++kA+Pk+ilelm+v+gLt+e+v+SHLQkYRl Kalax.0011s0116.2.p 218 KPRVVWSVELHQQFVSAVNQL-GIDKAVPKKILELMNVPGLTRENVASHLQKYRL 271 79*****************.******************************8 PP
2	Response_reg	73.6	7.9e-25	38	146	1	109
EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHH CS Response_reg 1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedale 88 vl+vdD+p+ + +l+++l++ y ev+ + +e al ll e++ +D+++ D+ mp+mdG++ll++ e +lp+i+++a ++++ + + Kalax.0011s0116.2.p 38 VLVVDDDPTCLAILERMLKSCLY-EVTKCNRAEVALSLLLENKngYDVVISDVHMPDMDGFKLLEHVGLEM-DLPVIMMSADDTKAVVMK 125 89*******************.***********777778******************6644.8************* PP HHHTTESEEEESS--HHHHHH CS Response_reg 89 alkaGakdflsKpfdpeelvk 109 + Ga d+l Kp+ +++l + Kalax.0011s0116.2.p 126 GVTHGACDYLIKPVRMDALKN 146 **************99976 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PIRSF	PIRSF036392	9.9E-171	9	664	IPR017053	Response regulator B-type, plant
SuperFamily	SSF52172	1.37E-34	35	160	IPR011006	CheY-like superfamily
Gene3D	G3DSA:3.40.50.2300	7.2E-42	35	180	No hit	No description
SMART	SM00448	8.6E-30	36	148	IPR001789	Signal transduction response regulator, receiver domain
PROSITE profile	PS50110	41.459	37	152	IPR001789	Signal transduction response regulator, receiver domain
Pfam	PF00072	1.7E-22	38	146	IPR001789	Signal transduction response regulator, receiver domain
CDD	cd00156	5.24E-27	39	151	No hit	No description
SuperFamily	SSF46689	3.94E-20	215	275	IPR009057	Homeodomain-like
PROSITE profile	PS51294	10.732	215	274	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	2.0E-30	217	276	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	7.9E-25	218	271	IPR006447	Myb domain, plants
Pfam	PF00249	6.2E-8	220	270	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0000160	Biological Process	phosphorelay signal transduction system
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 677 aa Download sequence Send to blast
MNLSSGGNRS MSAVASSCGG NWRPVDAVSD SFPAGLRVLV VDDDPTCLAI LERMLKSCLY 60 EVTKCNRAEV ALSLLLENKN GYDVVISDVH MPDMDGFKLL EHVGLEMDLP VIMMSADDTK 120 AVVMKGVTHG ACDYLIKPVR MDALKNIWQH VVRKKKHEWK DLEQSRSGEE AENRLAKQTE 180 EADYSSSANE GGSWRNSKRH KEEEEDVDDR DDTSTLKKPR VVWSVELHQQ FVSAVNQLGI 240 DKAVPKKILE LMNVPGLTRE NVASHLQKYR LYLRRISGGV PQHPGVLLNN GFMGSQEGPF 300 GAMSSLTGLD LQAIAASGHL PAQSLAGIQS AVFNKGNTLP GMTMAGIDQR NIFSFENPKT 360 RFGEVQQLQQ MANGKQINLL HGIPTNMESK QLTSLHHSES SIGSVNMQPS PHSNSSGSLM 420 MQAPQPQSRA QLLNEAAGAQ LSKIPSSIGP LSISNGIGVV RMRNNNPAHD NRRTGFSLVS 480 KPAPVTSFSM DNSELPGNSF PLASAPGVTA AKGTLHDETN SRIKGPVGYG LNYDMFNETH 540 QLRSHPWQLR ALEVQFEGSH RPNNLQGNFD ISPSVKVQQQ NYSVGTTLNA GSAPAVYSSG 600 ERMQQPYGAQ NTSQQITGHS SVKIKGESMS DFDSLPQPYG QEDLMSALLK QHPGSNGAAD 660 DGFDFGGYPP IGNIPV*

Sequence ? help Back to Top

Protein Sequence Length: 677 aa Download sequence Send to blast

MNLSSGGNRS MSAVASSCGG NWRPVDAVSD SFPAGLRVLV VDDDPTCLAI LERMLKSCLY  60
EVTKCNRAEV ALSLLLENKN GYDVVISDVH MPDMDGFKLL EHVGLEMDLP VIMMSADDTK  120
AVVMKGVTHG ACDYLIKPVR MDALKNIWQH VVRKKKHEWK DLEQSRSGEE AENRLAKQTE  180
EADYSSSANE GGSWRNSKRH KEEEEDVDDR DDTSTLKKPR VVWSVELHQQ FVSAVNQLGI  240
DKAVPKKILE LMNVPGLTRE NVASHLQKYR LYLRRISGGV PQHPGVLLNN GFMGSQEGPF  300
GAMSSLTGLD LQAIAASGHL PAQSLAGIQS AVFNKGNTLP GMTMAGIDQR NIFSFENPKT  360
RFGEVQQLQQ MANGKQINLL HGIPTNMESK QLTSLHHSES SIGSVNMQPS PHSNSSGSLM  420
MQAPQPQSRA QLLNEAAGAQ LSKIPSSIGP LSISNGIGVV RMRNNNPAHD NRRTGFSLVS  480
KPAPVTSFSM DNSELPGNSF PLASAPGVTA AKGTLHDETN SRIKGPVGYG LNYDMFNETH  540
QLRSHPWQLR ALEVQFEGSH RPNNLQGNFD ISPSVKVQQQ NYSVGTTLNA GSAPAVYSSG  600
ERMQQPYGAQ NTSQQITGHS SVKIKGESMS DFDSLPQPYG QEDLMSALLK QHPGSNGAAD  660
DGFDFGGYPP IGNIPV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1irz_A	3e-22	217	277	4	64	ARR10-B
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Regulates SHY2 by binding to its promoter (PubMed:19039136). Involved in the root-meristem size determination through the regulation of cell differentiation (PubMed:17363254). {ECO:0000269\|PubMed:11574878, ECO:0000269\|PubMed:11691951, ECO:0000269\|PubMed:17363254, ECO:0000269\|PubMed:19039136}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by gibberellin. {ECO:0000269\|PubMed:20605455}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023916952.1	0.0	two-component response regulator ARR2-like isoform X1
Swissprot	Q940D0	1e-176	ARR1_ARATH; Two-component response regulator ARR1
TrEMBL	B9RZK5	0.0	B9RZK5_RICCO; Two-component response regulator
STRING	XP_002519174.1	0.0	(Ricinus communis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G16857.1	1e-171	response regulator 1

Link Out ? help Back to Top
Phytozome	Kalax.0011s0116.2.p

Publications ? help Back to Top
Bürkle L,Meyer S,Dortay H,Lehrach H,Heyl A In vitro recombination cloning of entire cDNA libraries in Arabidopsis thaliana and its application to the yeast two-hybrid system. Funct. Integr. Genomics, 2005. 5(3): p. 175-83 [PMID:15714319] Moubayidin L, et al. Spatial coordination between stem cell activity and cell differentiation in the root meristem. Dev. Cell, 2013. 26(4): p. 405-15 [PMID:23987513] Takahashi N, et al. Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots. Curr. Biol., 2013. 23(18): p. 1812-7 [PMID:24035544] Kurepa J,Li Y,Perry SE,Smalle JA Ectopic expression of the phosphomimic mutant version of Arabidopsis response regulator 1 promotes a constitutive cytokinin response phenotype. BMC Plant Biol., 2014. 14: p. 28 [PMID:24423196] Cortleven A, et al. A novel protective function for cytokinin in the light stress response is mediated by the Arabidopsis histidine kinase2 and Arabidopsis histidine kinase3 receptors. Plant Physiol., 2014. 164(3): p. 1470-83 [PMID:24424319] Marín-de la Rosa N, et al. Genome Wide Binding Site Analysis Reveals Transcriptional Coactivation of Cytokinin-Responsive Genes by DELLA Proteins. PLoS Genet., 2015. 11(7): p. e1005337 [PMID:26134422] D'Alessandro S,Golin S,Hardtke CS,Lo Schiavo F,Zottini M The co-chaperone p23 controls root development through the modulation of auxin distribution in the Arabidopsis root meristem. J. Exp. Bot., 2015. 66(16): p. 5113-22 [PMID:26163704] Jiang L, et al. Strigolactones spatially influence lateral root development through the cytokinin signaling network. J. Exp. Bot., 2016. 67(1): p. 379-89 [PMID:26519957] Moubayidin L, et al. A SCARECROW-based regulatory circuit controls Arabidopsis thaliana meristem size from the root endodermis. Planta, 2016. 243(5): p. 1159-68 [PMID:26848984] Muraro D, et al. A multi-scale model of the interplay between cell signalling and hormone transport in specifying the root meristem of Arabidopsis thaliana. J. Theor. Biol., 2016. 404: p. 182-205 [PMID:27157127] Cortleven A, et al. Cytokinin Regulates the Etioplast-Chloroplast Transition through the Two-Component Signaling System and Activation of Chloroplast-Related Genes. Plant Physiol., 2016. 172(1): p. 464-78 [PMID:27388681] Kobayashi K, et al. Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling. Plant Physiol., 2017. 173(4): p. 2340-2355 [PMID:28193764] Zhang TQ, et al. A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration. Plant Cell, 2017. 29(5): p. 1073-1087 [PMID:28389585] Kushwah S,Laxmi A The interaction between glucose and cytokinin signaling in controlling Arabidopsis thaliana seedling root growth and development. Plant Signal Behav, 2017. 12(5): p. e1312241 [PMID:28467152] Meng WJ, et al. Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL. Plant Cell, 2017. 29(6): p. 1357-1372 [PMID:28576846] Kobayashi K,Iwase A Simultaneous but spatially different regulation of non-photosynthetic callus formation and photosynthetic root development after shoot removal. Plant Signal Behav, 2017. 12(6): p. e1338999 [PMID:28594268] Liu B,De Storme N,Geelen D Cold interferes with male meiotic cytokinesis in Arabidopsis thaliana independently of the AHK2/3-AHP2/3/5 cytokinin signaling module. Cell Biol. Int., 2017. 41(8): p. 879-889 [PMID:28618065] Zhang F,May A,Irish VF Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL. Trends Plant Sci., 2017. 22(10): p. 815-817 [PMID:28886911] Yan Z, et al. Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1. Plant Physiol., 2017. 175(3): p. 1438-1454 [PMID:28931628] Rong XF, et al. Type-B ARRs Control Carpel Regeneration Through Mediating AGAMOUS Expression in Arabidopsis. Plant Cell Physiol., 2018. 59(4): p. 756-764 [PMID:29186581] Bustillo-Avendaño E, et al. Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis. Plant Physiol., 2018. 176(2): p. 1709-1727 [PMID:29233938] Waldie T,Leyser O Cytokinin Targets Auxin Transport to Promote Shoot Branching. Plant Physiol., 2018. 177(2): p. 803-818 [PMID:29717021]