PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe

Family

C2H2

Protein Properties

Length: 428aa MW: 47252 Da PI: 8.5418

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Kalax.0002s0317.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	18.6	5e-06	58	80	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 y+C++C++ F r nL+ H r+H Kalax.0002s0317.1.p 58 YVCEICNQGFQRDQNLQMHRRRH 80 9*********************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.24E-5	57	80	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.7E-5	57	80	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.97	58	80	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0052	58	80	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	60	80	IPR007087	Zinc finger, C2H2
SMART	SM00355	98	109	139	IPR015880	Zinc finger, C2H2-like
SuperFamily	SSF57667	2.24E-5	140	165	No hit	No description
SMART	SM00355	130	145	172	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 428 aa Download sequence Send to blast
MLDHQASSNN NTARTASTSS FQNGLSSSKR KRRPAGTPDP DAEVVALSPK TLLESDRYVC 60 EICNQGFQRD QNLQMHRRRH KVPWKLVRRD DNGSGNDGGG NQEARKRVYV CPEPSCLHHD 120 ASHALGDLVG IKKHFRRKHS NYKQWVCDKC CKGYAVQSDY KAHLKTCGTR GHSCDCGRVF 180 SRVESFIEHQ DACTIKRVDP PQHQRLPTAF QPACSSSTSP SGCGETASLA MSHFQRVMKQ 240 IPKVIQHQEP LSQHSNHPQQ HNLHELQLLP SSSNTTTALY DDKNETALLK LSMGISCGGQ 300 PRGEEEATIM RVAVAEKEYA EEVRRRSKRE LELAELEFEN AKRMRQQALG ELERAKALRD 360 QAVKKISSTM MQITCQACQQ QFQASANAAA APPLLPIMSE ESSHAVSFIS SAVSEGDGGD 420 GGGGGHR*

Sequence ? help Back to Top

Protein Sequence Length: 428 aa Download sequence Send to blast

MLDHQASSNN NTARTASTSS FQNGLSSSKR KRRPAGTPDP DAEVVALSPK TLLESDRYVC  60
EICNQGFQRD QNLQMHRRRH KVPWKLVRRD DNGSGNDGGG NQEARKRVYV CPEPSCLHHD  120
ASHALGDLVG IKKHFRRKHS NYKQWVCDKC CKGYAVQSDY KAHLKTCGTR GHSCDCGRVF  180
SRVESFIEHQ DACTIKRVDP PQHQRLPTAF QPACSSSTSP SGCGETASLA MSHFQRVMKQ  240
IPKVIQHQEP LSQHSNHPQQ HNLHELQLLP SSSNTTTALY DDKNETALLK LSMGISCGGQ  300
PRGEEEATIM RVAVAEKEYA EEVRRRSKRE LELAELEFEN AKRMRQQALG ELERAKALRD  360
QAVKKISSTM MQITCQACQQ QFQASANAAA APPLLPIMSE ESSHAVSFIS SAVSEGDGGD  420
GGGGGHR*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	2e-16	143	193	5	55	Zinc finger protein JACKDAW
5b3h_F	2e-16	143	193	5	55	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in inflorescence stems gravitropism, probably by regulating starch accumulation in amyloplasts of graviperceptive cells. Required for stem circumnutation movements. Regulates lateral organ morphogenesis and gravitropic responses (PubMed:24039602). Acts cooperatively with IDD16 to control silique and branche orientation (PubMed:24039602). Involved in the establishment of auxin gradients through the regulation of auxin biosynthesis and transport (PubMed:24039602). {ECO:0000269\|PubMed:16813575, ECO:0000269\|PubMed:18259878, ECO:0000269\|PubMed:24039602, ECO:0000269\|PubMed:9210330}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not regulated by auxin. {ECO:0000269\|PubMed:24039602}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006448065.1	1e-162	protein SHOOT GRAVITROPISM 5
Swissprot	F4IPE3	1e-141	IDD15_ARATH; Zinc finger protein SHOOT GRAVITROPISM 5
TrEMBL	A0A2P2IQP4	1e-163	A0A2P2IQP4_RHIMU; Uncharacterized protein
STRING	XP_006448065.1	1e-162	(Citrus clementina)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G68130.1	1e-119	indeterminate(ID)-domain 14

Link Out ? help Back to Top
Phytozome	Kalax.0002s0317.1.p

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kim JY,Ryu JY,Baek K,Park CM High temperature attenuates the gravitropism of inflorescence stems by inducing SHOOT GRAVITROPISM 5 alternative splicing in Arabidopsis. New Phytol., 2016. 209(1): p. 265-79 [PMID:26256266] Ryu JY,Kim JY,Park CM Adaptive thermal control of stem gravitropism through alternative RNA splicing in Arabidopsis. Plant Signal Behav, 2015. 10(11): p. e1093715 [PMID:26452406] Qu Y, et al. Peroxisomal CuAOζ and its product H2O2 regulate the distribution of auxin and IBA-dependent lateral root development in Arabidopsis. J. Exp. Bot., 2017. 68(17): p. 4851-4867 [PMID:28992128] Shi H, et al. Zinc finger of Arabidopsis thaliana 6 is involved in melatonin-mediated auxin signaling through interacting INDETERMINATE DOMAIN15 and INDOLE-3-ACETIC ACID 17. J. Pineal Res., 2018. 65(2): p. e12494 [PMID:29607541]