PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Kaladp0630s0020.1.p

Organism

Kalanchoe laxiflora

Taxonomic ID

1670617

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe

Family

TCP

Protein Properties

Length: 609aa MW: 67915.1 Da PI: 9.0388

Description

TCP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Kaladp0630s0020.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	TCP	116.8	2.8e-36	238	356	2	106
TCP 2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgt..............ssssaseceaes 77 +g+kdrhsk++T++g+RdRRvRlsa++a++f+d+qd+LG+d++sk+++WL+++ak+ai+el+++ ++++ +++++++ Kaladp0630s0020.1.p 238 TGRKDRHSKVCTAKGPRDRRVRLSAHTAIQFYDVQDRLGYDRPSKAVDWLIKKAKAAIDELAELppwhptattiiptaTTTATNASSQQE 327 79**************************************************************98888776555443222222222222 PP TCP 78 ssssasnsssg.......kaaksaakskksqksaas 106 + + + a++ + +++++++ ++ Kaladp0630s0020.1.p 328 RMI-------HgqvansmEDANDYTIQHQQHERVEN 356 222.......23332222333333333333322222 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF03634	1.6E-34	238	351	IPR005333	Transcription factor, TCP
PROSITE profile	PS51369	34.295	240	298	IPR017887	Transcription factor TCP subgroup

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009793	Biological Process	embryo development ending in seed dormancy
GO:0009965	Biological Process	leaf morphogenesis
GO:0030154	Biological Process	cell differentiation
GO:0045962	Biological Process	positive regulation of development, heterochronic
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 609 aa Download sequence Send to blast
MARTFGRGKS RNIWFQKSKS KTRRRRREGT RRNRLRRAEC TSNRSCRSRS SSNQKLEGPK 60 HTSSLSLDPH RNQHHPHHHH LYHLTQQSLN SRYVEEEEQN IDEEEGEEEE DPDQSSPKSQ 120 GAEPQQPFHT QPFPYFSNSQ QQQLHQDLQL QQQQLYARLA QQQQLQLQQP VPSPGKKRSY 180 FSPPPPSSTF AEQNSQHALQ SNMGERSSQR QTTSRLGMRN SGGGEIIEVQ GGHIVRSTGR 240 KDRHSKVCTA KGPRDRRVRL SAHTAIQFYD VQDRLGYDRP SKAVDWLIKK AKAAIDELAE 300 LPPWHPTATT IIPTATTTAT NASSQQERMI HGQVANSMED ANDYTIQHQQ HERVENENNP 360 SFLPPSMDSD SIADTIKTFF PMGASAEPTS GSGMQFYPPD LLSRTSSSQN NQDLRLSLQS 420 FQDSQFLHSH HHQQHPGQTP QAIFSGNQLG FDASSGGGGW SDHQSTDINR FHRLMAWNNA 480 GGDTAGGSGG GGGGGSGGFM FNSLPPPPLS QPSLQQLFGQ SGHFFTQRGP LQSSNTSSVR 540 AWIDQPIANH HQHHQTLHDH SSTLSGIGNF QIPGAFPGFR IPARIQGDNE EQDNIHNKQS 600 SASSDSRH*

Sequence ? help Back to Top

Protein Sequence Length: 609 aa Download sequence Send to blast

MARTFGRGKS RNIWFQKSKS KTRRRRREGT RRNRLRRAEC TSNRSCRSRS SSNQKLEGPK  60
HTSSLSLDPH RNQHHPHHHH LYHLTQQSLN SRYVEEEEQN IDEEEGEEEE DPDQSSPKSQ  120
GAEPQQPFHT QPFPYFSNSQ QQQLHQDLQL QQQQLYARLA QQQQLQLQQP VPSPGKKRSY  180
FSPPPPSSTF AEQNSQHALQ SNMGERSSQR QTTSRLGMRN SGGGEIIEVQ GGHIVRSTGR  240
KDRHSKVCTA KGPRDRRVRL SAHTAIQFYD VQDRLGYDRP SKAVDWLIKK AKAAIDELAE  300
LPPWHPTATT IIPTATTTAT NASSQQERMI HGQVANSMED ANDYTIQHQQ HERVENENNP  360
SFLPPSMDSD SIADTIKTFF PMGASAEPTS GSGMQFYPPD LLSRTSSSQN NQDLRLSLQS  420
FQDSQFLHSH HHQQHPGQTP QAIFSGNQLG FDASSGGGGW SDHQSTDINR FHRLMAWNNA  480
GGDTAGGSGG GGGGGSGGFM FNSLPPPPLS QPSLQQLFGQ SGHFFTQRGP LQSSNTSSVR  540
AWIDQPIANH HQHHQTLHDH SSTLSGIGNF QIPGAFPGFR IPARIQGDNE EQDNIHNKQS  600
SASSDSRH*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5zkt_A	1e-19	245	298	1	54	Putative transcription factor PCF6
5zkt_B	1e-19	245	298	1	54	Putative transcription factor PCF6
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor playing a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164) (PubMed:12931144, PubMed:17307931). Required during early steps of embryogenesis (PubMed:15634699). Participates in ovule develpment (PubMed:25378179). Activates LOX2 expression by binding to the 5'-GGACCA-3' motif found in its promoter (PubMed:18816164). {ECO:0000269\|PubMed:12931144, ECO:0000269\|PubMed:15634699, ECO:0000269\|PubMed:17307931, ECO:0000269\|PubMed:18816164, ECO:0000269\|PubMed:25378179}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00009	PBM	Transfer from 929286	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by the miRNA miR-JAW/miR319 (PubMed:12931144, PubMed:18816164). {ECO:0000269\|PubMed:12931144, ECO:0000269\|PubMed:18816164}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021652538.1	1e-134	transcription factor TCP4
Swissprot	Q8LPR5	1e-97	TCP4_ARATH; Transcription factor TCP4
TrEMBL	A0A067KVJ7	1e-128	A0A067KVJ7_JATCU; Uncharacterized protein
STRING	cassava4.1_004517m	1e-130	(Manihot esculenta)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G15030.3	2e-80	TCP family protein

Link Out ? help Back to Top
Phytozome	Kaladp0630s0020.1.p

Publications ? help Back to Top
Schommer C, et al. Control of jasmonate biosynthesis and senescence by miR319 targets. PLoS Biol., 2008. 6(9): p. e230 [PMID:18816164] Ju Y, et al. Arabidopsis JINGUBANG Is a Negative Regulator of Pollen Germination That Prevents Pollination in Moist Environments. Plant Cell, 2016. 28(9): p. 2131-2146 [PMID:27468890] Challa KR,Aggarwal P,Nath U Activation of YUCCA5 by the Transcription Factor TCP4 Integrates Developmental and Environmental Signals to Promote Hypocotyl Elongation in Arabidopsis. Plant Cell, 2016. 28(9): p. 2117-2130 [PMID:27597774] Alvarez JP,Furumizu C,Efroni I,Eshed Y,Bowman JL Active suppression of a leaf meristem orchestrates determinate leaf growth. Elife, 2017. [PMID:27710768] Li J, et al. RABBIT EARS regulates the transcription of TCP4 during petal development in Arabidopsis. J. Exp. Bot., 2016. 67(22): p. 6473-6480 [PMID:27838638] Sun X, et al. Activation of secondary cell wall biosynthesis by miR319-targeted TCP4 transcription factor. Plant Biotechnol. J., 2017. 15(10): p. 1284-1294 [PMID:28233945] Kubota A, et al. TCP4-dependent induction of CONSTANS transcription requires GIGANTEA in photoperiodic flowering in Arabidopsis. PLoS Genet., 2017. 13(6): p. e1006856 [PMID:28628608] Koyama T,Sato F,Ohme-Takagi M Roles of miR319 and TCP Transcription Factors in Leaf Development. Plant Physiol., 2017. 175(2): p. 874-885 [PMID:28842549] Bresso EG,Chorostecki U,Rodriguez RE,Palatnik JF,Schommer C Spatial Control of Gene Expression by miR319-Regulated TCP Transcription Factors in Leaf Development. Plant Physiol., 2018. 176(2): p. 1694-1708 [PMID:29133375] Vadde BVL,Challa KR,Nath U The TCP4 transcription factor regulates trichome cell differentiation by directly activating GLABROUS INFLORESCENCE STEMS in Arabidopsis thaliana. Plant J., 2018. 93(2): p. 259-269 [PMID:29165850] Challa KR,Rath M,Nath U The CIN-TCP transcription factors promote commitment to differentiation in Arabidopsis leaf pavement cells via both auxin-dependent and independent pathways. PLoS Genet., 2019. 15(2): p. e1007988 [PMID:30742619]