PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Gesneriaceae; Didymocarpoideae; Trichosporeae; Loxocarpinae; Dorcoceras

Family

SBP

Protein Properties

Length: 548aa MW: 61426.1 Da PI: 8.7224

Description

SBP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KZV51957.1	genome	CNU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	SBP	56.1	9.7e-18	69	120	2	53
-SSTT-----TT--HHHHHTT--HHHHT-S-EEETTEEEEE-TTTSSEEETT CS SBP 2 CqvegCeadlseakeyhrrhkvCevhskapvvlvsgleqrfCqqCsrfhels 53 C+v++C+ad++eak y++r+kv e+h+ka+vvlv+ ++qrfCqq srf +l+ KZV51957.1 69 CHVQDCTADMNEAKPYYHRKKVREFHAKASVVLVAMRQQRFCQQYSRFESLN 120 ************************************************9985 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:4.10.1100.10	1.0E-17	62	120	IPR004333	Transcription factor, SBP-box
PROSITE profile	PS51141	13.785	66	143	IPR004333	Transcription factor, SBP-box
SuperFamily	SSF103612	1.28E-15	68	119	IPR004333	Transcription factor, SBP-box
Pfam	PF03110	3.5E-13	69	120	IPR004333	Transcription factor, SBP-box
PROSITE profile	PS50089	9.14	183	219	IPR001841	Zinc finger, RING-type
CDD	cd00162	4.33E-9	183	222	No hit	No description
Gene3D	G3DSA:3.30.40.10	5.3E-10	186	238	IPR013083	Zinc finger, RING/FYVE/PHD-type
Pfam	PF13923	6.4E-8	187	218	No hit	No description
SuperFamily	SSF57850	7.73E-10	189	233	No hit	No description
PROSITE pattern	PS00518	0	195	204	IPR017907	Zinc finger, RING-type, conserved site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0001709	Biological Process	cell fate determination
GO:0010076	Biological Process	maintenance of floral meristem identity
GO:0010077	Biological Process	maintenance of inflorescence meristem identity
GO:0010492	Biological Process	maintenance of shoot apical meristem identity
GO:0045814	Biological Process	negative regulation of gene expression, epigenetic
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0035102	Cellular Component	PRC1 complex
GO:0003677	Molecular Function	DNA binding
GO:0005515	Molecular Function	protein binding
GO:0008270	Molecular Function	zinc ion binding

Sequence ? help Back to Top
Protein Sequence Length: 548 aa Download sequence Send to blast
MIKNNCLFSL GLSSARGWKQ ERKKEGKRVV KEPVFDHAEY GLVEDIAEVD NKGALAPSGA 60 GGSTTRRYCH VQDCTADMNE AKPYYHRKKV REFHAKASVV LVAMRQQRFC QQYSRFESLN 120 FAKPPPPLVK LRRYLIDPMP AQKRSLEATT PPPSPPPLLE EEKADDSLQS GENHIHEPAE 180 NSCGIIRKTR TVMECLHRFC RECIDKSMRL GNNECPACRT HCASRRSLRD DPNYDALIAA 240 LYPDIDKYEE EELAFHEEER ARNKQIQASI AQTFRRQAEA LGKKRTSARA TTATFVRRQG 300 SYRNLRTRRN HRAIENQGSD DEEANGHDGS KDSSSADERS TEVKSKRYKR WGGARTSQPS 360 SGANADGGCD DNDSEANREV LGASAGLVVS TEILAWGRGG IRSNTRYGVP NGAGGKISRN 420 SRLSKLINRL QCANENNEAL KISVMLVSLH EEKISSLKRP YLCCSPTSSV KHLCQYVAQQ 480 TSLEASEIEI LMVKDFHPVN NTSKLKKEPG LSNPCYNELE LLNEHQTLGI VHAHFTQQNL 540 VSLFLGQI

Sequence ? help Back to Top

Protein Sequence Length: 548 aa Download sequence Send to blast

MIKNNCLFSL GLSSARGWKQ ERKKEGKRVV KEPVFDHAEY GLVEDIAEVD NKGALAPSGA  60
GGSTTRRYCH VQDCTADMNE AKPYYHRKKV REFHAKASVV LVAMRQQRFC QQYSRFESLN  120
FAKPPPPLVK LRRYLIDPMP AQKRSLEATT PPPSPPPLLE EEKADDSLQS GENHIHEPAE  180
NSCGIIRKTR TVMECLHRFC RECIDKSMRL GNNECPACRT HCASRRSLRD DPNYDALIAA  240
LYPDIDKYEE EELAFHEEER ARNKQIQASI AQTFRRQAEA LGKKRTSARA TTATFVRRQG  300
SYRNLRTRRN HRAIENQGSD DEEANGHDGS KDSSSADERS TEVKSKRYKR WGGARTSQPS  360
SGANADGGCD DNDSEANREV LGASAGLVVS TEILAWGRGG IRSNTRYGVP NGAGGKISRN  420
SRLSKLINRL QCANENNEAL KISVMLVSLH EEKISSLKRP YLCCSPTSSV KHLCQYVAQQ  480
TSLEASEIEI LMVKDFHPVN NTSKLKKEPG LSNPCYNELE LLNEHQTLGI VHAHFTQQNL  540
VSLFLGQI

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ckl_B	3e-19	185	278	63	158	UBIQUITIN LIGASE PROTEIN RING2
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Putative E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119ub), thereby playing a central role in histone code and gene regulation. {ECO:0000250}.; FUNCTION: As part of the PRC1-like complex, repress class I KNOX gene expression. PcG PRC1 complex maintains the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. {ECO:0000269\|PubMed:19097900}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KZV51957.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011096337.1	0.0	putative E3 ubiquitin-protein ligase RING1a isoform X1
Swissprot	Q9FKW0	5e-96	RNG1A_ARATH; Putative E3 ubiquitin-protein ligase RING1a
TrEMBL	A0A2Z7D158	0.0	A0A2Z7D158_9LAMI; Ring finger protein
STRING	XP_002509447.1	1e-149	(Ricinus communis)
STRING	XP_006449375.1	1e-149	(Citrus clementina)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G53160.2	2e-13	squamosa promoter binding protein-like 4

Publications ? help Back to Top
Xu L,Shen WH Polycomb silencing of KNOX genes confines shoot stem cell niches in Arabidopsis. Curr. Biol., 2008. 18(24): p. 1966-71 [PMID:19097900] Chen D,Molitor A,Liu C,Shen WH The Arabidopsis PRC1-like ring-finger proteins are necessary for repression of embryonic traits during vegetative growth. Cell Res., 2010. 20(12): p. 1332-44 [PMID:21060339] Peng L, et al. Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch. J. Mol. Biol., 2018. 430(21): p. 4245-4259 [PMID:30176245]