PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Gesneriaceae; Didymocarpoideae; Trichosporeae; Loxocarpinae; Dorcoceras

Family

HD-ZIP

Protein Properties

Length: 235aa MW: 27255.3 Da PI: 7.0781

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KZV49469.1	genome	CNU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	60.3	3e-19	30	83	3	56
--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 3 kRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 k+++++ eq+++Le+ Fe+ +++ e++ +LA+ lgL+ rqV +WFqNrRa++k KZV49469.1 30 KKRRLNMEQVKALEKSFEMGNKLEPERKMQLARALGLQPRQVAIWFQNRRARWK 83 456899***********************************************9 PP
2	HD-ZIP_I/II	132	2.3e-42	29	120	1	92
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelk 92 ekkrrl+ eqvk+LE+sFe+ +kLeperK++lar+Lglqprqva+WFqnrRAR+ktkqlEkdy++Lkr+++alk +n++L++++++L+++l KZV49469.1 29 EKKRRLNMEQVKALEKSFEMGNKLEPERKMQLARALGLQPRQVAIWFQNRRARWKTKQLEKDYDVLKRQFEALKLDNDALKSQNTKLQSQLL 120 69**************************************************************************************9985 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	5.13E-20	24	87	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.038	25	85	IPR001356	Homeobox domain
SMART	SM00389	3.8E-19	28	89	IPR001356	Homeobox domain
Pfam	PF00046	1.7E-16	30	83	IPR001356	Homeobox domain
CDD	cd00086	7.35E-16	30	86	No hit	No description
Gene3D	G3DSA:1.10.10.60	5.6E-20	32	92	IPR009057	Homeodomain-like
PRINTS	PR00031	6.5E-6	56	65	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	60	83	IPR017970	Homeobox, conserved site
PRINTS	PR00031	6.5E-6	65	81	IPR000047	Helix-turn-helix motif
Pfam	PF02183	1.0E-15	85	125	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 235 aa Download sequence Send to blast
MRRSMSFSGL DGDEREDEMS DDGSQMLGEK KRRLNMEQVK ALEKSFEMGN KLEPERKMQL 60 ARALGLQPRQ VAIWFQNRRA RWKTKQLEKD YDVLKRQFEA LKLDNDALKS QNTKLQSQLL 120 ALKGREPRVV STAINLNKEN EACWSNGSDD TYQVVNLNAV STLDDTQNND DNNKNVVVFP 180 SSPDISAPNQ ADRFQNHKIN NYHHPPSSNH QIFNMFGNID GGQNFWPWHE QQNYQ

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	77	85	RRARWKTKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor that may act in the sucrose-signaling pathway. {ECO:0000269\|PubMed:11292072}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KZV49469.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011098601.1	8e-94	homeobox-leucine zipper protein HOX21
Swissprot	Q8LC03	1e-65	ATB13_ARATH; Homeobox-leucine zipper protein ATHB-13
TrEMBL	A0A2Z7CXT2	1e-174	A0A2Z7CXT2_9LAMI; Homeobox-leucine zipper protein ATHB-13
STRING	XP_004135187.1	8e-81	(Cucumis sativus)
STRING	XP_004155316.1	8e-81	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA848	24	98

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G69780.1	2e-68	HD-ZIP family protein

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Ribone PA,Capella M,Chan RL Functional characterization of the homeodomain leucine zipper I transcription factor AtHB13 reveals a crucial role in Arabidopsis development. J. Exp. Bot., 2015. 66(19): p. 5929-43 [PMID:26136262] Wang X, et al. Overexpressed BRH1, a RING finger gene, alters rosette leaf shape in Arabidopsis thaliana. Sci China Life Sci, 2018. 61(1): p. 79-87 [PMID:28887625] Ebrahimian-Motlagh S, et al. JUNGBRUNNEN1 Confers Drought Tolerance Downstream of the HD-Zip I Transcription Factor AtHB13. Front Plant Sci, 2017. 8: p. 2118 [PMID:29326734]