PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
|
Home TFext BLAST Prediction Download Help About Links PlantRegMap |
Transcription Factor Information
Basic Information? help Back to Top | |||||||||
---|---|---|---|---|---|---|---|---|---|
TF ID | KHN31932.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
|
||||||||
Family | C2H2 | ||||||||
Protein Properties | Length: 1309aa MW: 149112 Da PI: 8.6115 | ||||||||
Description | C2H2 family protein | ||||||||
Gene Model |
|
Signature Domain? help Back to Top | |||||||
---|---|---|---|---|---|---|---|
No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | zf-C2H2 | 12.7 | 0.00038 | 1193 | 1218 | 1 | 23 |
EEET..TTTEEESSHHHHHHHHHH.T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt.H 23 y+C C++sF +k +L++H r+ + KHN31932.1 1193 YRCDidGCTMSFGSKQELMHHKRNiC 1218 99********************9877 PP | |||||||
2 | zf-C2H2 | 13 | 0.00031 | 1218 | 1240 | 3 | 23 |
ET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 3 Cp..dCgksFsrksnLkrHirtH 23 Cp Cgk F ++ +L++H r+H KHN31932.1 1218 CPvkGCGKKFFSHKYLVQHRRVH 1240 9999*****************99 PP | |||||||
3 | zf-C2H2 | 13.7 | 0.00018 | 1276 | 1302 | 1 | 23 |
EEET..TTTEEESSHHHHHHHHHH..T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt..H 23 y+C dCg++F+ s++ rH r+ H KHN31932.1 1276 YVCAepDCGQTFRFVSDFSRHKRKtgH 1302 899999****************99666 PP |
Protein Features ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Database | Entry ID | E-value | Start | End | InterPro ID | Description |
PROSITE profile | PS51184 | 15.809 | 1 | 64 | IPR003347 | JmjC domain |
Pfam | PF02373 | 8.7E-14 | 1 | 47 | IPR003347 | JmjC domain |
SuperFamily | SSF51197 | 8.79E-9 | 9 | 82 | No hit | No description |
Gene3D | G3DSA:3.30.160.60 | 6.6E-4 | 1182 | 1215 | IPR013087 | Zinc finger C2H2-type/integrase DNA-binding domain |
SMART | SM00355 | 7.7 | 1193 | 1215 | IPR015880 | Zinc finger, C2H2-like |
SMART | SM00355 | 0.0045 | 1216 | 1240 | IPR015880 | Zinc finger, C2H2-like |
PROSITE profile | PS50157 | 12.944 | 1216 | 1245 | IPR007087 | Zinc finger, C2H2 |
Gene3D | G3DSA:3.30.160.60 | 1.4E-6 | 1217 | 1244 | IPR013087 | Zinc finger C2H2-type/integrase DNA-binding domain |
PROSITE pattern | PS00028 | 0 | 1218 | 1240 | IPR007087 | Zinc finger, C2H2 |
SuperFamily | SSF57667 | 1.79E-9 | 1232 | 1274 | No hit | No description |
Gene3D | G3DSA:3.30.160.60 | 9.7E-9 | 1245 | 1270 | IPR013087 | Zinc finger C2H2-type/integrase DNA-binding domain |
SMART | SM00355 | 0.0014 | 1246 | 1270 | IPR015880 | Zinc finger, C2H2-like |
PROSITE profile | PS50157 | 10.741 | 1246 | 1275 | IPR007087 | Zinc finger, C2H2 |
PROSITE pattern | PS00028 | 0 | 1248 | 1270 | IPR007087 | Zinc finger, C2H2 |
SuperFamily | SSF57667 | 5.76E-8 | 1264 | 1298 | No hit | No description |
Gene3D | G3DSA:3.30.160.60 | 6.2E-9 | 1271 | 1299 | IPR013087 | Zinc finger C2H2-type/integrase DNA-binding domain |
SMART | SM00355 | 1.1 | 1276 | 1302 | IPR015880 | Zinc finger, C2H2-like |
PROSITE profile | PS50157 | 11.697 | 1276 | 1307 | IPR007087 | Zinc finger, C2H2 |
PROSITE pattern | PS00028 | 0 | 1278 | 1302 | IPR007087 | Zinc finger, C2H2 |
Gene Ontology ? help Back to Top | ||||||
---|---|---|---|---|---|---|
GO Term | GO Category | GO Description | ||||
GO:0032259 | Biological Process | methylation | ||||
GO:0055114 | Biological Process | oxidation-reduction process | ||||
GO:0003676 | Molecular Function | nucleic acid binding | ||||
GO:0008168 | Molecular Function | methyltransferase activity | ||||
GO:0016491 | Molecular Function | oxidoreductase activity | ||||
GO:0046872 | Molecular Function | metal ion binding |
Sequence ? help Back to Top |
---|
Protein Sequence Length: 1309 aa Download sequence Send to blast |
MSPEVLISAG VPCCRLVQNA GEFVVTFPRA YHTGFSHGFN CGEAANIATP EWLRFAKDAA 60 IRRASLNYPP MVSHFQLLYD LALALCSRIP VSISAEPRSS RLKDKKGEGE TVTKELFVQD 120 VLQNNDLLHI LGKGSDVVLL PRSSVDISVC SKLRVGSQQS INVRNSEGMH SSKGFVSDDL 180 VFNRSPGIKQ EKSFYFVKDK FTTLCERNRI STFNVNGNIS TASSNPLQRD NDRETSQGDG 240 LSDQRLFSCV TCGILCFSCV AIVQPREPAA RYLMSADCSF FNDWVVGSGV SSNKLTIAHE 300 DATITEPNMY TGRKHVYLFG WMKNNVQDGK HDVTVQSSRE ALNTESENGN TALALLASAY 360 GNSSDSEEDH ITDDSHESNV INSASECLLS HTQNSHASPM TALDRDDNIP STSATCENFM 420 HRRFECNLNH QSVDHSLKKP DYHITSEVKF ENTKMVPNFT SNCSQHTHDA DRSLSNKSMV 480 PFDNKNTSMV LQSDEDSSRM HVFCLEHAAE AEQQLRPIGG AHMLLLCHPD YPKIESEAKM 540 VAEDLGIDYM WKNIAYRHAS TEDEERIQSA LDNEEAIPGN GDWAVKLGIN LFYSANLSRS 600 PLYSKQMPYN SVIYYSFGCS SLASSPIEPK VYQRRVNRQK KVVAGKWCGK VWMSNQVHPL 660 LAKRDSEDVE DEKLILGWIL PDEKFEKSGS TPKRETTSRK SGKKRKMTAE NGRPRKGSYA 720 KKNLVADNST EDKHNSQPRR ILRNKKARFV ERDHAALKGD YSPSYHRKPI SKQANCSESD 780 AVSDDSLDDD DHMQQSRNVK VEKAKFMDND VVSNDTMDYD SDCQQREEHS SKQVEDMERD 840 ANSEDFLDVG SLQLQRKTSR AMHAKSINEE DIISDDQMES PFRKRQKRIP KNRQGKYLTG 900 KDIISDNQLE LKMKKQQRMN PKSRQAKYLN EEDIASDDQL EDHYRRYQRN PKGRQATCVA 960 GEDEMSDDQL ENHCQKQQTN FSRKRQNKGN VREVKNEMCD DQLEDHFLKQ HRRFPKSRQN 1020 KHTEKEVMND LAENNSHLLH RTPKRKQAKC MEEDMNSDDE MEDDQPLRRA LRSKQAKPKT 1080 LLKQANSFQA KKQASRPIKQ GSRLLVKSKA PQQIKQPAHL WNKQSNNTQE FSLYMEEEED 1140 GGPSTRLRKR ATKAQESEGK LKDKQTKRKK VKNAAAAKVS VGHAKMKDGE AEYRCDIDGC 1200 TMSFGSKQEL MHHKRNICPV KGCGKKFFSH KYLVQHRRVH EDERPLKCPW KGCKMTFKWA 1260 WARTEHIRVH TGARPYVCAE PDCGQTFRFV SDFSRHKRKT GHSAKKNCQ |
3D Structure ? help Back to Top | ||||||
---|---|---|---|---|---|---|
PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
6a57_A | 3e-69 | 1191 | 1307 | 21 | 137 | Lysine-specific demethylase REF6 |
6a58_A | 3e-69 | 1191 | 1307 | 21 | 137 | Lysine-specific demethylase REF6 |
6a59_A | 3e-69 | 1191 | 1307 | 21 | 137 | Lysine-specific demethylase REF6 |
Search in ModeBase |
Nucleic Localization Signal ? help Back to Top | |||
---|---|---|---|
No. | Start | End | Sequence |
1 | 1147 | 1169 | RKRATKAQESEGKLKDKQTKRKK |
Functional Description ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Source | Description | |||||
UniProt | Histone demethylase that demethylates 'Lys-27' (H3K27me) of histone H3. Demethylates both tri- (H3K27me3) and di-methylated (H3K27me2) H3K27me (PubMed:21642989, PubMed:27111035). Demethylates also H3K4me3/2 and H3K36me3/2 in an in vitro assay (PubMed:20711170). Involved in the transcriptional regulation of hundreds of genes regulating developmental patterning and responses to various stimuli (PubMed:18467490). Binds DNA via its four zinc fingers in a sequence-specific manner, 5'-CTCTGYTY-3', to promote the demethylation of H3K27me3 and the regulation of organ boundary formation (PubMed:27111034, PubMed:27111035). Involved in the regulation of flowering time by repressing FLOWERING LOCUS C (FLC) expression (PubMed:15377760). Interacts with the NF-Y complexe to regulate SOC1 (PubMed:25105952). Mediates the recruitment of BRM to its target loci (PubMed:27111034). {ECO:0000269|PubMed:15377760, ECO:0000269|PubMed:18467490, ECO:0000269|PubMed:20711170, ECO:0000269|PubMed:21642989, ECO:0000269|PubMed:25105952, ECO:0000269|PubMed:27111034, ECO:0000269|PubMed:27111035}. |
Cis-element ? help Back to Top | |
---|---|
Source | Link |
PlantRegMap | KHN31932.1 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Source | Hit ID | E-value | Description | |||
GenBank | AC235340 | 0.0 | AC235340.1 Glycine max strain Williams 82 clone GM_WBb0086A04, complete sequence. |
Annotation -- Protein ? help Back to Top | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-value | Description | ||||
Refseq | XP_028236974.1 | 0.0 | lysine-specific demethylase REF6-like | ||||
Swissprot | Q9STM3 | 1e-110 | REF6_ARATH; Lysine-specific demethylase REF6 | ||||
TrEMBL | A0A0B2RJC7 | 0.0 | A0A0B2RJC7_GLYSO; Lysine-specific demethylase REF6 | ||||
STRING | GLYMA06G18290.2 | 0.0 | (Glycine max) |
Orthologous Group ? help Back to Top | |||
---|---|---|---|
Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF5648 | 32 | 50 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Hit ID | E-value | Description | ||||
AT3G48430.1 | 1e-112 | relative of early flowering 6 |