PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

KHN18971.1

Organism

Glycine soja

Taxonomic ID

3848

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja

Family

MYB

Protein Properties

Length: 311aa MW: 35625.1 Da PI: 5.0322

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KHN18971.1	genome	TCUHK	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	41.1	4e-13	13	58	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 +g W +eEde l++ vk++G+++W++I ++ + Rt+k+c++rw + KHN18971.1 13 KGQWEAEEDEVLLNHVKKYGPRDWSSIRSKGLLQRTGKSCRLRWVN 58 799**********************8887799********87 PP
2	Myb_DNA-binding	43.1	9.9e-14	69	108	3	44
SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHH CS Myb_DNA-binding 3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrw 44 +++ eE+ +++ +q+G++ W++Ia++++ gRt++++k++w KHN18971.1 69 KFSLEEERVVIELQAQFGNR-WAKIASYLP-GRTDNDVKNFW 108 799***************.*****.********* PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	2.2E-20	6	61	IPR009057	Homeodomain-like
PROSITE profile	PS51294	14.107	8	60	IPR017930	Myb domain
SMART	SM00717	1.6E-9	12	62	IPR001005	SANT/Myb domain
SuperFamily	SSF46689	1.45E-27	12	108	IPR009057	Homeodomain-like
Pfam	PF13921	5.2E-13	16	75	No hit	No description
CDD	cd00167	1.42E-10	16	60	No hit	No description
PROSITE profile	PS51294	19.463	61	116	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	5.7E-18	62	114	IPR009057	Homeodomain-like
SMART	SM00717	6.6E-13	66	114	IPR001005	SANT/Myb domain
CDD	cd00167	1.26E-10	69	108	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 311 aa Download sequence Send to blast
MHGKKEQEEY IRKGQWEAEE DEVLLNHVKK YGPRDWSSIR SKGLLQRTGK SCRLRWVNKL 60 RPNLKNGCKF SLEEERVVIE LQAQFGNRWA KIASYLPGRT DNDVKNFWSS RQKRLARILQ 120 TSATTFRSQK NKTKVPSFLD VPTLEAPKFS SSSEGEPSSK PQTCTLPYID NSEVIQMVSL 180 PDLIKSELPS SDTIHVEQEF TLFENYKSTE QIAFPQIPEL QNGLTFSMEN QDLVPTIEEP 240 CFIEDLCPFD VSEFGIGPQH PFGFPFFEPP GSCRFGTRDA IDNFKISDSF FDDLPVDMFD 300 HMDPPASPSN L

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h8a_C	7e-27	11	114	25	126	MYB TRANSFORMING PROTEIN
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that acts as a positive regulator of male germline development by promoting both gametic cell specification and cell cycle progression (PubMed:15694308, PubMed:15618418, PubMed:19300502, PubMed:21285328). Binds to canonical MYB sites 5'-AACCGTC-3', 5'-AAACCGC-3' and 5'-AACCGT-3' in promoters to trigger the expression of male germline-specific or enriched genes (e.g. MGH3, GEX2 and GCS1), including those required for fertilization (PubMed:21285328, PubMed:19300502). Required for sperm cell specification leading to pollen maturation by activating a germline-specific regulon (PubMed:21285328, PubMed:15694308, PubMed:15618418, PubMed:19300502). Involved in pollen mitosis entry at G2-M transition via the regulation of CYCB1-1, DAZ1 and DAZ2 expression (PubMed:15618418, PubMed:19300502, PubMed:24876252). {ECO:0000269\|PubMed:15618418, ECO:0000269\|PubMed:15694308, ECO:0000269\|PubMed:19300502, ECO:0000269\|PubMed:21285328, ECO:0000269\|PubMed:24876252}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KHN18971.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by the microRNA 159 (miR159); the production of miR159 is stimulated by the anaphase promoting complex/cyclosome (APC/C) (PubMed:21441434). Activated by ARID1 in male germline cells via specific histone acetylation regulation (e.g. H3K9Ac) (PubMed:25057814). {ECO:0000269\|PubMed:21441434, ECO:0000269\|PubMed:25057814}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AP015042	1e-111	AP015042.1 Vigna angularis var. angularis DNA, chromosome 9, almost complete sequence, cultivar: Shumari.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003520442.1	0.0	transcription factor DUO1
Refseq	XP_028223798.1	0.0	transcription factor DUO1-like
Swissprot	A0A178VEK7	1e-80	DUO1_ARATH; Transcription factor DUO1
TrEMBL	A0A445LA98	0.0	A0A445LA98_GLYSO; Transcription factor DUO1 (Fragment)
STRING	GLYMA03G26830.2	0.0	(Glycine max)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF3693	31	64

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G60460.1	4e-76	MYB family protein

Publications ? help Back to Top
Qi X, et al. Identification of a novel salt tolerance gene in wild soybean by whole-genome sequencing. Nat Commun, 2014. 5: p. 4340 [PMID:25004933] Zheng B,He H,Zheng Y,Wu W,McCormick S An ARID domain-containing protein within nuclear bodies is required for sperm cell formation in Arabidopsis thaliana. PLoS Genet., 2014. 10(7): p. e1004421 [PMID:25057814] Peters B, et al. A Conserved cis-Regulatory Module Determines Germline Fate through Activation of the Transcription Factor DUO1 Promoter. Plant Physiol., 2017. 173(1): p. 280-293 [PMID:27624837] Zheng Z, et al. Target RNA Secondary Structure Is a Major Determinant of miR159 Efficacy. Plant Physiol., 2017. 174(3): p. 1764-1778 [PMID:28515145]