PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KHN16291.1
Organism
Glycine soja
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
Family E2F/DP
Protein Properties Length: 344aa    MW: 39643.3 Da    PI: 10.454
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KHN16291.1genomeTCUHKView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP339.9e-111253147
     E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiY 47
                rk+ksL+ll+++fl+l++k+  + + l+++a++L    v  +rRRiY
  KHN16291.1 12 RKQKSLGLLCTNFLSLYNKEGVRLIGLDDAASRL---GV--ERRRIY 53
                79*****************999************...**..****** PP
2E2F_TDP69.25.1e-22111172161
     E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.dvknkrRRiYDilNVLealnliek 61 
                 r+eksL lltq+f+kl+ +s+ ++++l+e+ak L+ + + ++k+RR+YDi+NVL+++nliek
  KHN16291.1 111 RREKSLALLTQNFVKLFVCSNFEMISLDEAAKLLLGNaNNRTKVRRLYDIANVLSSMNLIEK 172
                 689*******************************9999999********************* PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.107.1E-12868IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467858.16E-51165IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.4E-91267IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.7E-61353IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.109.9E-20107184IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.18E-11110177IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.3E-20111191IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.1E-17113174IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 344 aa     Download sequence    Send to blast
MSSLSTHHTY SRKQKSLGLL CTNFLSLYNK EGVRLIGLDD AASRLGVERR RIYILARKAK  60
NQCTWKGFSA IHVALQELKV HDDEDEEETF PNINTGSQNV MVKSSSKNEN RREKSLALLT  120
QNFVKLFVCS NFEMISLDEA AKLLLGNANN RTKVRRLYDI ANVLSSMNLI EKVIFSSVHF  180
KFPHRALQWK CCFLYSVLIN YSKLMMSLRR LQTHTTNTRK PAFRWLGVRG KTWSESAQTN  240
VKESQKRMFG SDITNINFKR KVDLSMDGQN FKTQNQQENI SPRAQLEKKS LKKDAKQTSM  300
SYQFGPFAPA YVHKVGTSEN NSVKQVQDWE SLAQEHRPQY QNQG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A1e-24111733222Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapKHN16291.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006578605.10.0E2F transcription factor-like E2FE isoform X3
RefseqXP_006578606.10.0E2F transcription factor-like E2FE isoform X3
RefseqXP_028229180.10.0E2F transcription factor-like E2FE isoform X3
RefseqXP_028229182.10.0E2F transcription factor-like E2FE isoform X3
SwissprotQ8LSZ43e-84E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A0B2Q4130.0A0A0B2Q413_GLYSO; E2F transcription factor-like E2FE
STRINGGLYMA04G34870.30.0(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36683366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.12e-88DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Qi X, et al.
    Identification of a novel salt tolerance gene in wild soybean by whole-genome sequencing.
    Nat Commun, 2014. 5: p. 4340
    [PMID:25004933]
  3. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  4. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]