PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis

Family

Nin-like

Protein Properties

Length: 956aa MW: 105193 Da PI: 5.7939

Description

Nin-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KFK28956.1	genome	MPIPBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	RWP-RK	91.9	4.9e-29	585	635	2	52
RWP-RK 2 ekeisledlskyFslpikdAAkeLgvclTvLKriCRqyGIkRWPhRkiksl 52 ek+isl++l++yF +++kdAAk+Lgvc+T++KriCRq+GI+RWP+Rkik++ KFK28956.1 585 EKTISLDVLQQYFTGSLKDAAKSLGVCPTTMKRICRQHGISRWPSRKIKKV 635 799**********************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF55781	3.53E-5	207	278	IPR029016	GAF domain-like
PROSITE profile	PS51519	17.757	574	655	IPR003035	RWP-RK domain
Pfam	PF02042	7.3E-26	587	635	IPR003035	RWP-RK domain
PROSITE profile	PS51745	27.211	860	942	IPR000270	PB1 domain
Pfam	PF00564	9.5E-20	860	941	IPR000270	PB1 domain
SuperFamily	SSF54277	1.31E-22	860	945	No hit	No description
Gene3D	G3DSA:3.10.20.240	3.4E-27	860	942	No hit	No description
SMART	SM00666	1.5E-27	860	942	IPR000270	PB1 domain
CDD	cd06407	2.14E-34	861	941	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009414	Biological Process	response to water deprivation
GO:0010118	Biological Process	stomatal movement
GO:0010167	Biological Process	response to nitrate
GO:0042128	Biological Process	nitrate assimilation
GO:0005634	Cellular Component	nucleus
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 956 aa Download sequence Send to blast
MCEPDENAVN PPTSRSRELL MDVDDLDLDG SWPLDQIPYL SSSNRMIFPS FVTSSSEQPC 60 SPLWAFSDGA GTGLHGGGGG GGDDEKINSG VPSLRLADYP IFLPYASSSV AENASQKQNS 120 FQFPSPLMSL VPSENADNYC VIKERMTQAL RYFKESTEQH VLAQVWAPVR KNGRDLLTTL 180 GQPFVLNPNG NGLNQYRMIS LTYMFSVDSE SDIELGLPGR VFRQKLPEWT PNVQYYSSKE 240 FSRLDHALHY NVRGTLALPV FNPSGQSCIG VVELIMTSEK IHYAPEVDRV CKALEAVNLK 300 SSEILDHQTT QICNESRQNA LAEILEVLTV VCETHNLPLA QTWVPCQHGS VLANGGGLKK 360 NCTSFDGSCM GQVCMSTTDM ACYVVDAHVW GFRDACLEHH LQKGQGVAGR AFLNGGSCFC 420 RDITKFCKTQ YPLVHYALMF KLTTCFAISL QSSYTGDDSY ILEFFLPSSI TDHQEQDSLL 480 GSLLVTMKEH FQSLRVASGV DFGEDDDKLS FEIIQALPDK KIHSEIESIR VPFSGFKSNT 540 KEAPPLIPQP VVQSCDPVNV KINVATVNGV VKEKKKTEKK RGKTEKTISL DVLQQYFTGS 600 LKDAAKSLGV CPTTMKRICR QHGISRWPSR KIKKVNRSIT KLKRVIESVQ GTDGGLDLTS 660 MAVSSIPWTH GQTAAQPLNS PNGSKPPELP NANNSPNHWS SDHSPQEANG SPELPSNGHK 720 RSRTVDESAG TPTSHGSCDG NQLDETKFQN QDPLFTVGGS PPGLLFPPYP RDHDVSAASF 780 SMPNRLLGTI DPFRGMPIKD AGSSKDLRNL CSSAAFEDRF PDSNWMNNDN NSNNNNIYAS 840 PKEEAVANIT REPSGSEIRT VTIKASYKED IIRFRISSGS GIMELKDEVA KRLKVDAGTF 900 DIKYLDDDNE WVLIACDADL QECLEIPRSS RTNIVRLLVH DVTTNLGSSC ESTGEL

Sequence ? help Back to Top

Protein Sequence Length: 956 aa Download sequence Send to blast

MCEPDENAVN PPTSRSRELL MDVDDLDLDG SWPLDQIPYL SSSNRMIFPS FVTSSSEQPC  60
SPLWAFSDGA GTGLHGGGGG GGDDEKINSG VPSLRLADYP IFLPYASSSV AENASQKQNS  120
FQFPSPLMSL VPSENADNYC VIKERMTQAL RYFKESTEQH VLAQVWAPVR KNGRDLLTTL  180
GQPFVLNPNG NGLNQYRMIS LTYMFSVDSE SDIELGLPGR VFRQKLPEWT PNVQYYSSKE  240
FSRLDHALHY NVRGTLALPV FNPSGQSCIG VVELIMTSEK IHYAPEVDRV CKALEAVNLK  300
SSEILDHQTT QICNESRQNA LAEILEVLTV VCETHNLPLA QTWVPCQHGS VLANGGGLKK  360
NCTSFDGSCM GQVCMSTTDM ACYVVDAHVW GFRDACLEHH LQKGQGVAGR AFLNGGSCFC  420
RDITKFCKTQ YPLVHYALMF KLTTCFAISL QSSYTGDDSY ILEFFLPSSI TDHQEQDSLL  480
GSLLVTMKEH FQSLRVASGV DFGEDDDKLS FEIIQALPDK KIHSEIESIR VPFSGFKSNT  540
KEAPPLIPQP VVQSCDPVNV KINVATVNGV VKEKKKTEKK RGKTEKTISL DVLQQYFTGS  600
LKDAAKSLGV CPTTMKRICR QHGISRWPSR KIKKVNRSIT KLKRVIESVQ GTDGGLDLTS  660
MAVSSIPWTH GQTAAQPLNS PNGSKPPELP NANNSPNHWS SDHSPQEANG SPELPSNGHK  720
RSRTVDESAG TPTSHGSCDG NQLDETKFQN QDPLFTVGGS PPGLLFPPYP RDHDVSAASF  780
SMPNRLLGTI DPFRGMPIKD AGSSKDLRNL CSSAAFEDRF PDSNWMNNDN NSNNNNIYAS  840
PKEEAVANIT REPSGSEIRT VTIKASYKED IIRFRISSGS GIMELKDEVA KRLKVDAGTF  900
DIKYLDDDNE WVLIACDADL QECLEIPRSS RTNIVRLLVH DVTTNLGSSC ESTGEL

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in regulation of nitrate assimilation and in transduction of the nitrate signal. {ECO:0000269\|PubMed:18826430}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00449	DAP	Transfer from AT4G24020	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KFK28956.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not regulated by the N source or by nitrate. {ECO:0000269\|PubMed:18826430}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK228452	0.0	AK228452.1 Arabidopsis thaliana mRNA for hypothetical protein, complete cds, clone: RAFL15-03-P13.
GenBank	BT005776	0.0	BT005776.1 Arabidopsis thaliana clone RAFL15-03-P13 (R20174) unknown protein (At4g24020) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006413484.1	0.0	protein NLP7
Refseq	XP_024005488.1	0.0	protein NLP7
Swissprot	Q84TH9	0.0	NLP7_ARATH; Protein NLP7
TrEMBL	A0A087GGF4	0.0	A0A087GGF4_ARAAL; Uncharacterized protein
STRING	A0A087GGF4	0.0	(Arabis alpina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2507	26	66

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G24020.1	0.0	NIN like protein 7

Publications ? help Back to Top
Xu N, et al. The Arabidopsis NRG2 Protein Mediates Nitrate Signaling and Interacts with and Regulates Key Nitrate Regulators. Plant Cell, 2016. 28(2): p. 485-504 [PMID:26744214] Karve R,Suárez-Román F,Iyer-Pascuzzi AS The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release. Plant Physiol., 2016. 171(3): p. 2101-11 [PMID:27221617] Yu LH, et al. Overexpression of Arabidopsis NLP7 improves plant growth under both nitrogen-limiting and -sufficient conditions by enhancing nitrogen and carbon assimilation. Sci Rep, 2016. 6: p. 27795 [PMID:27293103] Menz J,Li Z,Schulze WX,Ludewig U Early nitrogen-deprivation responses in Arabidopsis roots reveal distinct differences on transcriptome and (phospho-) proteome levels between nitrate and ammonium nutrition. Plant J., 2016. 88(5): p. 717-734 [PMID:27419465] Yan D, et al. NIN-like protein 8 is a master regulator of nitrate-promoted seed germination in Arabidopsis. Nat Commun, 2016. 7: p. 13179 [PMID:27731416] Guan P, et al. Interacting TCP and NLP transcription factors control plant responses to nitrate availability. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(9): p. 2419-2424 [PMID:28202720] Liu KH, et al. Discovery of nitrate-CPK-NLP signalling in central nutrient-growth networks. Nature, 2017. 545(7654): p. 311-316 [PMID:28489820] Li Z, et al. The Arabidopsis CPSF30-L gene plays an essential role in nitrate signaling and regulates the nitrate transceptor gene NRT1.1. New Phytol., 2017. 216(4): p. 1205-1222 [PMID:28850721] Cao H, et al. Overexpression of the Maize ZmNLP6 and ZmNLP8 Can Complement the Arabidopsis Nitrate Regulatory Mutant nlp7 by Restoring Nitrate Signaling and Assimilation. Front Plant Sci, 2017. 8: p. 1703 [PMID:29051766] Konishi N,Okubo T,Yamaya T,Hayakawa T,Minamisawa K Nitrate Supply-Dependent Shifts in Communities of Root-Associated Bacteria in Arabidopsis. Microbes Environ., 2017. 32(4): p. 314-323 [PMID:29187692] Karve RA,Iyer-Pascuzzi AS Further insights into the role of NIN-LIKE PROTEIN 7 (NLP7) in root cap cell release. Plant Signal Behav, 2018. 13(1): p. e1414122 [PMID:29215953] Zhao L, et al. The Arabidopsis NLP7 gene regulates nitrate signaling via NRT1.1-dependent pathway in the presence of ammonium. Sci Rep, 2018. 8(1): p. 1487 [PMID:29367694]