PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis

Family

HD-ZIP

Protein Properties

Length: 216aa MW: 24860 Da PI: 6.2976

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KFK28350.1	genome	MPIPBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	60.8	2.1e-19	69	121	4	56
-SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 4 RttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 ++++t+eq++ Le F ++r++ ++e++A +lgL+ rqV vWFqNrRa++k KFK28350.1 69 KRKLTDEQVNMLEYSFGNERKLESGRKEKIAGELGLDPRQVAVWFQNRRARWK 121 4589************************************************9 PP
2	HD-ZIP_I/II	120.7	7.4e-39	68	159	2	93
HD-ZIP_I/II 2 kkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelke 93 +kr+l++eqv++LE sF +e+kLe+ rK+++a eLgl+prqvavWFqnrRAR+ktk++E++y++Lk+++d+++ +++Le++v eL+e+l++ KFK28350.1 68 RKRKLTDEQVNMLEYSFGNERKLESGRKEKIAGELGLDPRQVAVWFQNRRARWKTKKIEEEYAKLKSQHDTVVLGQCQLESQVLELTEQLSQ 159 8***************************************************************************************9986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00389	9.5E-17	66	127	IPR001356	Homeobox domain
SuperFamily	SSF46689	5.13E-17	66	124	IPR009057	Homeodomain-like
PROSITE profile	PS50071	15.985	68	123	IPR001356	Homeobox domain
CDD	cd00086	1.72E-14	68	124	No hit	No description
Pfam	PF00046	1.1E-16	69	121	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	6.5E-19	70	129	IPR009057	Homeodomain-like
PRINTS	PR00031	2.1E-5	94	103	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	98	121	IPR017970	Homeobox, conserved site
PRINTS	PR00031	2.1E-5	103	119	IPR000047	Helix-turn-helix motif

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009733	Biological Process	response to auxin
GO:0005634	Cellular Component	nucleus
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 216 aa Download sequence Send to blast
MDQMVIGSQV YPYTVQTQHS HCIIMNQIDG SSSLSGEGSK PVVKRRRKRR SKDSSATNDD 60 DVAGIMLRKR KLTDEQVNML EYSFGNERKL ESGRKEKIAG ELGLDPRQVA VWFQNRRARW 120 KTKKIEEEYA KLKSQHDTVV LGQCQLESQV LELTEQLSQA QNEIRKLSER LEGMSTNSPS 180 SSLSIEVNDA PIDFEFVPET NYNIPFYMEY WDGLYV

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	43	49	KRRRKRR
2	66	71	LRKRKL

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor that may play a regulatory role in auxin/cytokinin signaling during root development. {ECO:0000269\|PubMed:15567172}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00591	DAP	Transfer from AT5G66700	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KFK28350.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By abscisic acid (ABA), by salt stress, by indole-3-acetic acid (IAA) and during darkness conditions. Down-regulated by cytokinin. {ECO:0000269\|PubMed:15567172, ECO:0000269\|PubMed:16055682}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013596522.1	1e-115	PREDICTED: homeobox-leucine zipper protein ATHB-53 isoform X1
Swissprot	Q9LVR0	1e-107	ATB53_ARATH; Homeobox-leucine zipper protein ATHB-53
TrEMBL	A0A087GEP8	1e-160	A0A087GEP8_ARAAL; Uncharacterized protein
STRING	A0A087GEP8	1e-161	(Arabis alpina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM12602	17	31

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G66700.1	1e-109	homeobox 53

Publications ? help Back to Top
González-Grandío E, et al. Abscisic acid signaling is controlled by a BRANCHED1/HD-ZIP I cascade in Arabidopsis axillary buds. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(2): p. E245-E254 [PMID:28028241]