PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Jcr4S06393.50
Common NameJCGZ_11533, LOC105640442
Organism
Jatropha curcas
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Jatropheae; Jatropha
Family E2F/DP
Protein Properties Length: 388aa    MW: 43728.4 Da    PI: 8.4373
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Jcr4S06393.50genomeKazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP72.16e-232085171
        E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                   rk+ksL+ll+++fl+l+ +   +++ l+++a +L    v  +rRRiYDi+NVLe+++++++k+kn+++wkg
  Jcr4S06393.50 20 RKQKSLGLLCTNFLSLYDRDGIEVIGLDDAALKL---GV--ERRRIYDIVNVLESVGVLSRKAKNKYTWKG 85
                   79*****************999************...**..****************************98 PP
2E2F_TDP77.31.5e-24160240171
        E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                    rkeksL+lltq+f+k++ +s+ + ++l+e+ak L+ +      +++k+RR+YDi+NVL++l+liek     ++k+++rw g
  Jcr4S06393.50 160 RKEKSLGLLTQNFVKIFLCSKVNLISLDEAAKLLLGDvhnssIMRTKVRRLYDIANVLSSLKLIEKthtaeTRKPAFRWLG 240
                    79***************************************999**************************99*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.105.5E-261686IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.74E-151983IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.5E-272085IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023198.6E-202185IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.103.6E-23158241IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.9E-33160240IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023193.1E-19161240IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467853.4E-13162241IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 388 aa     Download sequence    Send to blast
MPVLPSEGPE SSCRHHTYSR KQKSLGLLCT NFLSLYDRDG IEVIGLDDAA LKLGVERRRI  60
YDIVNVLESV GVLSRKAKNK YTWKGFGAIP NALRELKEEG LRENLSSFDK QQSSNFEKVS  120
DDDNDDEDDW DSNPNIGSQN DNPIPSGIVK STAASRFDNR KEKSLGLLTQ NFVKIFLCSK  180
VNLISLDEAA KLLLGDVHNS SIMRTKVRRL YDIANVLSSL KLIEKTHTAE TRKPAFRWLG  240
LGGKSDSGLA DTLAEPKKRK FGVDVTNICF KRTKDDSSAN WSRCDNLKMH NQIKVEDVVT  300
IADRSNLDQD SQEGSKNYRF GPFAPVTVAK VGSSENKMTQ IHDMESLAST YRPQYHNQAL  360
KELFAHYMEA WKTWYTEVAG KKPIEQIS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A3e-39192323228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012080146.10.0E2F transcription factor-like E2FE
SwissprotQ8LSZ41e-133E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A067K4U30.0A0A067K4U3_JATCU; Uncharacterized protein
STRINGcassava4.1_009539m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36683366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-136DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Zhang L, et al.
    Global analysis of gene expression profiles in physic nut (Jatropha curcas L.) seedlings exposed to salt stress.
    PLoS ONE, 2014. 9(5): p. e97878
    [PMID:24837971]
  3. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  4. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]