PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Jatropheae; Jatropha

Family

C2H2

Protein Properties

Length: 528aa MW: 58067.8 Da PI: 6.4078

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Jcr4S05922.30	genome	Kazusa	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	14.7	9.2e-05	128	150	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++Cp+Cg+sF++ + H ++ Jcr4S05922.30 128 FECPICGQSFRSEGDVSIHVESC 150 89************999998776 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.10.20.90	7.1E-4	24	52	No hit	No description
PROSITE profile	PS50157	8.871	128	157	IPR007087	Zinc finger, C2H2
CDD	cd09212	1.05E-20	188	276	No hit	No description
SuperFamily	SSF143503	5.36E-18	194	275	IPR018997	PUB domain
SMART	SM00580	1.2E-16	194	261	IPR018997	PUB domain
Pfam	PF09409	2.2E-15	196	267	IPR018997	PUB domain
SuperFamily	SSF54236	6.72E-7	369	501	IPR029071	Ubiquitin-related domain
Gene3D	G3DSA:3.10.20.90	7.1E-4	385	431	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0050832	Biological Process	defense response to fungus
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 528 aa Download sequence Send to blast
MGDMKDKFKG FMKKVNTQLQ SSSSGKFKGQ GRVLGGGSAS SSSSGPVNPI HTPYSQPVNP 60 KPTPDPPSLN STSNSKPLPQ KTTNFEQIKP DSVNNPTPNR NSGGGFDPFD SLITTGKRSQ 120 NGYSLNTFEC PICGQSFRSE GDVSIHVESC VNNNNNNVNN GVVDGENELV ESSGKSELQA 180 SVVDAYLSGK TPDGSVQVVL RLFTNIVKEP DNAKFRKIRM GNPKIREAIT EVAGGIELLE 240 FVGFELKEDG GEMWAVLEVP DEERIRLINK VIELLEPKPV KDEASKIQDK PSVASAGTKE 300 QVEPKKIDRQ SVDMADSYVN GVRSLCNAEA YKFESHIRVF FSVPESVAAK IELPDSFYYL 360 SIDEVKREAD ARKKKIAESQ LLIPKSYREK QAKAARKRYK RTLIRIQFPD GVVLQGVFAP 420 WEQTTALYEL AVRGALGLVM VGDLLVSHSC KFVSSSLKDP SLEFELLDPV LVKRRVIPHF 480 PEAGQRASTL EDEDLVPSAL IKFRPLETDS SVFTGLCNEL LQISEPLN

Sequence ? help Back to Top

Protein Sequence Length: 528 aa Download sequence Send to blast

MGDMKDKFKG FMKKVNTQLQ SSSSGKFKGQ GRVLGGGSAS SSSSGPVNPI HTPYSQPVNP  60
KPTPDPPSLN STSNSKPLPQ KTTNFEQIKP DSVNNPTPNR NSGGGFDPFD SLITTGKRSQ  120
NGYSLNTFEC PICGQSFRSE GDVSIHVESC VNNNNNNVNN GVVDGENELV ESSGKSELQA  180
SVVDAYLSGK TPDGSVQVVL RLFTNIVKEP DNAKFRKIRM GNPKIREAIT EVAGGIELLE  240
FVGFELKEDG GEMWAVLEVP DEERIRLINK VIELLEPKPV KDEASKIQDK PSVASAGTKE  300
QVEPKKIDRQ SVDMADSYVN GVRSLCNAEA YKFESHIRVF FSVPESVAAK IELPDSFYYL  360
SIDEVKREAD ARKKKIAESQ LLIPKSYREK QAKAARKRYK RTLIRIQFPD GVVLQGVFAP  420
WEQTTALYEL AVRGALGLVM VGDLLVSHSC KFVSSSLKDP SLEFELLDPV LVKRRVIPHF  480
PEAGQRASTL EDEDLVPSAL IKFRPLETDS SVFTGLCNEL LQISEPLN

Functional Description ? help Back to Top
Source	Description
UniProt	Facilitates the interaction of SYP31 and CDC48A, thereby regulating an CDC48A membrane-associated function (Ref.8). Appears to act as a negative regulator mediating the powdery mildew-plant interaction (PubMed:19176722, PubMed:23301616). {ECO:0000269\|PubMed:19176722, ECO:0000269\|PubMed:23301616, ECO:0000269\|Ref.8}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced in response to powdery mildew and by benzothiadiazole (BTH) treatment. {ECO:0000269\|PubMed:19176722}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012072290.1	0.0	plant UBX domain-containing protein 2 isoform X1
Swissprot	Q9ZU93	0.0	PUX2_ARATH; Plant UBX domain-containing protein 2
TrEMBL	A0A067L1Y2	0.0	A0A067L1Y2_JATCU; Uncharacterized protein
STRING	XP_002525983.1	0.0	(Ricinus communis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8944	25	29

Publications ? help Back to Top
Suzuki T,Park H,Till EA,Lennarz WJ The PUB domain: a putative protein-protein interaction domain implicated in the ubiquitin-proteasome pathway. Biochem. Biophys. Res. Commun., 2001. 287(5): p. 1083-7 [PMID:11587532] Rancour DM,Park S,Knight SD,Bednarek SY Plant UBX domain-containing protein 1, PUX1, regulates the oligomeric structure and activity of arabidopsis CDC48. J. Biol. Chem., 2004. 279(52): p. 54264-74 [PMID:15498773] Chandran D,Rickert J,Cherk C,Dotson BR,Wildermuth MC Host cell ploidy underlying the fungal feeding site is a determinant of powdery mildew growth and reproduction. Mol. Plant Microbe Interact., 2013. 26(5): p. 537-45 [PMID:23301616]