PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Jcr4S00420.40

Common Name

ERF1, JCGZ_24640

Organism

Jatropha curcas

Taxonomic ID

180498

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Jatropheae; Jatropha

Family

ERF

Protein Properties

Length: 354aa MW: 39150.5 Da PI: 4.736

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Jcr4S00420.40	genome	Kazusa	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	61.1	2.6e-19	119	168	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +y+G+r+++ +g+W+AeIrdp++ r++lg+f taeeAa+a++a +++++g Jcr4S00420.40 119 QYRGIRQRP-WGKWAAEIRDPRK---GVRVWLGTFNTAEEAARAYDAEARRIRG 168 69*****.******954...4**********************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	2.94E-32	119	177	No hit	No description
SMART	SM00380	6.4E-38	119	182	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	2.6E-32	119	178	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	24.092	119	176	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	4.18E-22	119	177	IPR016177	DNA-binding domain
PRINTS	PR00367	1.0E-11	120	131	IPR001471	AP2/ERF domain
Pfam	PF00847	7.7E-12	120	168	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.0E-11	142	158	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0070483	Biological Process	detection of hypoxia
GO:0005634	Cellular Component	nucleus
GO:0005886	Cellular Component	plasma membrane
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 354 aa Download sequence Send to blast
MCGGAIISDF IPPAVAGRSS RRLTADFLWP DLKKPIGKQY SKPVVDLDND FEADFQEFKD 60 ESDADEEDDV MLDVKPFAFS ATASPPARNR SSSRGSAAVK SVEFNGQAEK SAKRKRKNQY 120 RGIRQRPWGK WAAEIRDPRK GVRVWLGTFN TAEEAARAYD AEARRIRGKK AKVNFPEEAP 180 HASPKRPSKA NSQKSLGKTN LAENLNYLDN PEQDYFNSMG FVEEKPPVSQ FGIMDSLPVN 240 GDAVSRLAKT PEISSVLSAT PEIDESLFIE DANPKKKLKS DSGNEAPAEE NNGKSLSDEL 300 LAFENQMNYQ MPYLEGSWEA SLDSFLNGDT TQDGGNPMDL WSFDDLAGMV GGVY

Sequence ? help Back to Top

Protein Sequence Length: 354 aa Download sequence Send to blast

MCGGAIISDF IPPAVAGRSS RRLTADFLWP DLKKPIGKQY SKPVVDLDND FEADFQEFKD  60
ESDADEEDDV MLDVKPFAFS ATASPPARNR SSSRGSAAVK SVEFNGQAEK SAKRKRKNQY  120
RGIRQRPWGK WAAEIRDPRK GVRVWLGTFN TAEEAARAYD AEARRIRGKK AKVNFPEEAP  180
HASPKRPSKA NSQKSLGKTN LAENLNYLDN PEQDYFNSMG FVEEKPPVSQ FGIMDSLPVN  240
GDAVSRLAKT PEISSVLSAT PEIDESLFIE DANPKKKLKS DSGNEAPAEE NNGKSLSDEL  300
LAFENQMNYQ MPYLEGSWEA SLDSFLNGDT TQDGGNPMDL WSFDDLAGMV GGVY

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	6e-21	118	178	13	74	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	273	279	PKKKLKS

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the activation of hypoxic gene expression and in ethylene response. Partially redundant with RAP2-2. Acts as a downstream regulator in the ethylene signaling pathway. {ECO:0000269\|PubMed:22020282, ECO:0000269\|PubMed:22530619}.

Function -- GeneRIF ? help Back to Top
Jatropha curcas ERF1 is a new member of the ERF transcription factors family that may play an important role in tolerance to environmental stress. [PMID: 25540008]

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00204	DAP	Transfer from AT1G53910	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by hypoxia but not by ethylene. {ECO:0000269\|PubMed:22020282}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HM776314	0.0	HM776314.1 Jatropha curcas ethylene-responsive transcription factor (ERF1) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001295665.1	0.0	ethylene-responsive transcription factor RAP2-12-like
Refseq	XP_012068806.1	0.0	ethylene-responsive transcription factor RAP2-12-like isoform X1
Swissprot	Q9SSA8	5e-77	RA212_ARATH; Ethylene-responsive transcription factor RAP2-12
TrEMBL	I6MBV0	0.0	I6MBV0_JATCU; Ethylene-responsive transcription factor
STRING	cassava4.1_009529m	0.0	(Manihot esculenta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4808	32	52

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G53910.3	2e-70	related to AP2 12

Link Out ? help Back to Top
Entrez Gene	105631335

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zhang L, et al. Global analysis of gene expression profiles in physic nut (Jatropha curcas L.) seedlings exposed to salt stress. PLoS ONE, 2014. 9(5): p. e97878 [PMID:24837971] Kosmacz M, et al. The stability and nuclear localization of the transcription factor RAP2.12 are dynamically regulated by oxygen concentration. Plant Cell Environ., 2015. 38(6): p. 1094-103 [PMID:25438831] Yang H, et al. Overexpression of the Jatropha curcas JcERF1 gene coding an AP2/ERF-type transcription factor increases tolerance to salt in transgenic tobacco. Biochemistry Mosc., 2014. 79(11): p. 1226-36 [PMID:25540008] Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana. Plant Sci., 2015. 236: p. 37-43 [PMID:26025519] Gasch P, et al. Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis. Plant Cell, 2016. 28(1): p. 160-80 [PMID:26668304] Gonzali S, et al. Universal stress protein HRU1 mediates ROS homeostasis under anoxia. Nat Plants, 2015. 1: p. 15151 [PMID:27251529] Paul MV, et al. Oxygen Sensing via the Ethylene Response Transcription Factor RAP2.12 Affects Plant Metabolism and Performance under Both Normoxia and Hypoxia. Plant Physiol., 2016. 172(1): p. 141-53 [PMID:27372243] Shahzad Z, et al. A Potassium-Dependent Oxygen Sensing Pathway Regulates Plant Root Hydraulics. Cell, 2016. 167(1): p. 87-98.e14 [PMID:27641502] Yao Y, et al. ETHYLENE RESPONSE FACTOR 74 (ERF74) plays an essential role in controlling a respiratory burst oxidase homolog D (RbohD)-dependent mechanism in response to different stresses in Arabidopsis. New Phytol., 2017. 213(4): p. 1667-1681 [PMID:28164334] Giuntoli B,Licausi F,van Veen H,Perata P Functional Balancing of the Hypoxia Regulators RAP2.12 and HRA1 Takes Place in vivo in Arabidopsis thaliana Plants. Front Plant Sci, 2017. 8: p. 591 [PMID:28487707] Yao Y,Chen X,Wu AM ERF-VII members exhibit synergistic and separate roles in Arabidopsis. Plant Signal Behav, 2017. 12(6): p. e1329073 [PMID:28537474] Eysholdt-Derzsó E,Sauter M Root Bending Is Antagonistically Affected by Hypoxia and ERF-Mediated Transcription via Auxin Signaling. Plant Physiol., 2017. 175(1): p. 412-423 [PMID:28698356] Giuntoli B, et al. Age-dependent regulation of ERF-VII transcription factor activity in Arabidopsis thaliana. Plant Cell Environ., 2017. 40(10): p. 2333-2346 [PMID:28741696]