PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Itr_sc003412.1_g00001.1
Organism
Ipomoea trifida
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Convolvulaceae; Ipomoeeae; Ipomoea
Family HD-ZIP
Protein Properties Length: 721aa    MW: 78723.3 Da    PI: 6.507
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Itr_sc003412.1_g00001.1genomeKazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox61.41.4e-192883156
                             TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
                 Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                             +++ +++t++q+++Le+ F+++++p++++r +L+++lgL  rq+k+WFqNrR+++k
  Itr_sc003412.1_g00001.1 28 KKRYHRHTANQIQRLESIFKECPHPDEKTRLQLSRELGLAPRQIKFWFQNRRTQMK 83
                             688999***********************************************998 PP
2START187.66.6e-592284522206
                              HHHHHHHHHHHHHHHC-TT-EEEE...EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S. CS
                    START   2 laeeaaqelvkkalaeepgWvkss...esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla. 77 
                              +a  a++el+++ + +e +W+ks    + +n + + + f+++ +       ++ea+r+sgvv+m++  lv  ++d + +W e ++ 
  Itr_sc003412.1_g00001.1 228 IAGNAMEELIRLLQGNESLWTKSLdgrDLLNLESYERVFPRASNhmknpnMRIEASRDSGVVIMNALALVDMFMDAN-KWVELFPt 312
                              67899*******************996555555555666665558999*****************************.******99 PP

                              ...EEEEEEEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEE CS
                    START  78 ...kaetlevissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgil 153
                                 ka+tlevissg      g+lqlm+ elq+lsplvp R f+f+R+++q ++g+w+ivdvS d++q++ +s+ + ++++lpSg+l
  Itr_sc003412.1_g00001.1 313 ivsKATTLEVISSGvlgsrsGTLQLMYEELQVLSPLVPtRQFYFLRFCQQIEQGSWAIVDVSYDVPQDNYQSPTSCKVHRLPSGCL 398
                              999******************************************************************99*************** PP

                              EEEECTCEEEEEEEE-EE--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
                    START 154 iepksnghskvtwvehvdlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                              i++++ng+s+vtwvehv+++++++ h l+r +++sg+a+ga +w+  lqr ce+
  Itr_sc003412.1_g00001.1 399 IQDMPNGYSNVTWVEHVEVEDKVIlHKLYRDVIQSGIAFGAERWLTVLQRMCER 452
                              ****************************************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466892.63E-20785IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.602.3E-221279IPR009057Homeodomain-like
PROSITE profilePS5007117.6212585IPR001356Homeobox domain
SMARTSM003893.4E-182789IPR001356Homeobox domain
PfamPF000462.9E-172883IPR001356Homeobox domain
CDDcd000866.25E-192886No hitNo description
PROSITE patternPS0002706083IPR017970Homeobox, conserved site
PROSITE profilePS5084847.98218455IPR002913START domain
SuperFamilySSF559617.69E-37219452No hitNo description
CDDcd088756.48E-117222451No hitNo description
SMARTSM002341.2E-47227452IPR002913START domain
PfamPF018525.2E-51228452IPR002913START domain
Gene3DG3DSA:3.30.530.202.4E-7280420IPR023393START-like domain
SuperFamilySSF559611.08E-13474636No hitNo description
SuperFamilySSF559611.08E-13669696No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 721 aa     Download sequence    Send to blast
MEFGGGAGGS SGSGSGDHHD PSDRNRNKKR YHRHTANQIQ RLESIFKECP HPDEKTRLQL  60
SRELGLAPRQ IKFWFQNRRT QMKAQHERAD NCALRAENDK IRCENIAIRE ALKNVICPSC  120
GGPPVREDSY FDEHKLRMEN MALKEELDKI SSIAAKYIGR PISQLPPVQP IHLSSLDLSM  180
SSYGGHGIPG GPSLDLDLLP GSSAAAIPGF PFPALSLSDM DRSLMADIAG NAMEELIRLL  240
QGNESLWTKS LDGRDLLNLE SYERVFPRAS NHMKNPNMRI EASRDSGVVI MNALALVDMF  300
MDANKWVELF PTIVSKATTL EVISSGVLGS RSGTLQLMYE ELQVLSPLVP TRQFYFLRFC  360
QQIEQGSWAI VDVSYDVPQD NYQSPTSCKV HRLPSGCLIQ DMPNGYSNVT WVEHVEVEDK  420
VILHKLYRDV IQSGIAFGAE RWLTVLQRMC ERFVCLMVSG SSSRDLGGVI PSAEGKRSMM  480
KLAQRMVNNF CGSVNPSNGH HWTTLSGANE FEVRATLQKS TDPGQPNGVV ISAATTIWLP  540
IPPQLWDVLS NQNPVQEVAH IANGSHPGNC ISVLRAYNTS QNNMLILQES CIDSSGCLVV  600
YSPVDLPAIN MAMSGEDPTY IPLLPSGFTI SPDGRSERGN SSKINIDQAS SSTSNPASST  660
STAAGGEGGS LITVVFQILV SSLPSAKMSP ESVATVNSLI GNTVHQIKSA LNCSAVPTSA  720
S
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_019167409.10.0PREDICTED: homeobox-leucine zipper protein HDG11
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A068TTE00.0A0A068TTE0_COFCA; Uncharacterized protein
STRINGXP_008240378.10.0(Prunus mume)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA24902351
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]