PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Convolvulaceae; Ipomoeeae; Ipomoea

Family

HD-ZIP

Protein Properties

Length: 823aa MW: 90376.9 Da PI: 6.4352

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Itr_sc001830.1_g00004.1	genome	Kazusa	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	57.2	2.8e-18	25	82	4	57
-SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS Homeobox 4 RttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57 ++t+eq+e+Le++++++++ps +r++L +++ +++ +q+kvWFqNrR +ek+ Itr_sc001830.1_g00004.1 25 YVRYTAEQVEALERVYAECPKPSSLRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 82 5789****************************************************97 PP
2	bZIP_1	19.8	1.7e-06	76	121	18	63
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 18 rrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklksev 63 rr+R++ ++e +L++ +L+a Nk L +e+++l+k+v++l se+ Itr_sc001830.1_g00004.1 76 RRCREKQRKESSRLQTVNRKLSAMNKLLMEENDRLQKQVSQLVSEN 121 9*****************************************9987 PP
3	START	150.9	1.1e-47	162	369	2	204
HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECT CS START 2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetleviss 87 +aee+++e+++ka+ ++ W +++ +++g++++ +f+ s+++s a+ra+g+v ++++ e+l d++ W +++++ e+ Itr_sc001830.1_g00004.1 162 IAEETLAEFLSKATGTAIDWIQMPGMKPGPDSVGIFAISHSCSRVAARACGLVSLEPTKIIEILKDRP-SWFRDCRSLEVFTMFPA 246 7899****************************************************8888888888.*******999999 PP T..EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEE CS START 88 g..galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwv 167 g g+++l +++ +a+++l+p Rdf+++Ry+ +l+ g++v++++S++ + p+ s++vRae+lpSg+li+p+++g+s +++v Itr_sc001830.1_g00004.1 247 GngGTIELLYTQIYAPTTLAPaRDFWTLRYTTTLENGSLVVCERSLSGTGAGPNasaASQFVRAEMLPSGYLIRPCEGGGSIIHIV 332 999*******************************************999999999*********************** PP E-EE--SSXXHHHHHHHHHHHHHHHHHHHHHHTXXXX CS START 168 ehvdlkgrlphwllrslvksglaegaktwvatlqrqc 204 +h +l++++++++lr+l++s+ + ++k++ a+l++ + Itr_sc001830.1_g00004.1 333 DHLNLEAWSVPEVLRPLYESSKVIAQKMTIAALRYIR 369 ******************************99865 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50071	15.143	19	83	IPR001356	Homeobox domain
SMART	SM00389	2.8E-15	21	87	IPR001356	Homeobox domain
SuperFamily	SSF46689	3.12E-16	23	85	IPR009057	Homeodomain-like
CDD	cd00086	4.62E-16	24	84	No hit	No description
Pfam	PF00046	7.3E-16	25	82	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	2.9E-18	26	82	IPR009057	Homeodomain-like
CDD	cd14686	4.73E-6	76	115	No hit	No description
PROSITE profile	PS50848	26.833	152	380	IPR002913	START domain
CDD	cd08875	4.67E-71	156	372	No hit	No description
SMART	SM00234	3.8E-35	161	371	IPR002913	START domain
Gene3D	G3DSA:3.30.530.20	3.8E-19	161	365	IPR023393	START-like domain
SuperFamily	SSF55961	7.14E-34	161	373	No hit	No description
Pfam	PF01852	3.5E-45	162	369	IPR002913	START domain
Pfam	PF08670	3.0E-48	679	822	IPR013978	MEKHLA

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding
GO:0008289	Molecular Function	lipid binding

Sequence ? help Back to Top
Protein Sequence Length: 823 aa Download sequence Send to blast
MAMVVHQHRE SSSGSIHKHL DAGKYVRYTA EQVEALERVY AECPKPSSLR RQQLIRECPI 60 LSNIEPKQIK VWFQNRRCRE KQRKESSRLQ TVNRKLSAMN KLLMEENDRL QKQVSQLVSE 120 NGFMRQHLRT APTTTDASCE SAVTTTHHSL RDASNPAGLL SIAEETLAEF LSKATGTAID 180 WIQMPGMKPG PDSVGIFAIS HSCSRVAARA CGLVSLEPTK IIEILKDRPS WFRDCRSLEV 240 FTMFPAGNGG TIELLYTQIY APTTLAPARD FWTLRYTTTL ENGSLVVCER SLSGTGAGPN 300 ASAASQFVRA EMLPSGYLIR PCEGGGSIIH IVDHLNLEAW SVPEVLRPLY ESSKVIAQKM 360 TIAALRYIRQ IAQETSGEVV YSLGRQPAVL RTFSQRLNRG FNDAINGFND DGWSVLSGDG 420 AEDVTVAINS TKSLGTTSNT LPNVPPAVLV RFLREHRSEW ADFNVDAYSA TALKTNSCAY 480 PGMRPTRFTG SQIIMPLGHT IEHEEMLEVI RLEGHSLGHE NAFISGDIHL LQMCRGIDEN 540 AVGACAELVF APIDEMFPDD APLLPSGFRI IPLDSISNDA QDTLNAQRTL DLTSSLEVGP 600 ATNTAQNASS SSCAARSLLT IAFQFPYEDN LQENVATMAR QYVRSVISSV QRVAMAISPT 660 GLGPTLGPKV SPGSPEALTL AQWINQSYSY HMGAQLLGTD SVGAESVLKN LWHHHDAILC 720 CSIKSLPVFI FANKAGLDML ETTLVALQDI TLDKIFDESG RKALFAELAK IMQQGFAYLA 780 GGICMSAMGR HISYEQAIAW KVVADDESTV HCLAFSFINW SFV

Sequence ? help Back to Top

Protein Sequence Length: 823 aa Download sequence Send to blast

MAMVVHQHRE SSSGSIHKHL DAGKYVRYTA EQVEALERVY AECPKPSSLR RQQLIRECPI  60
LSNIEPKQIK VWFQNRRCRE KQRKESSRLQ TVNRKLSAMN KLLMEENDRL QKQVSQLVSE  120
NGFMRQHLRT APTTTDASCE SAVTTTHHSL RDASNPAGLL SIAEETLAEF LSKATGTAID  180
WIQMPGMKPG PDSVGIFAIS HSCSRVAARA CGLVSLEPTK IIEILKDRPS WFRDCRSLEV  240
FTMFPAGNGG TIELLYTQIY APTTLAPARD FWTLRYTTTL ENGSLVVCER SLSGTGAGPN  300
ASAASQFVRA EMLPSGYLIR PCEGGGSIIH IVDHLNLEAW SVPEVLRPLY ESSKVIAQKM  360
TIAALRYIRQ IAQETSGEVV YSLGRQPAVL RTFSQRLNRG FNDAINGFND DGWSVLSGDG  420
AEDVTVAINS TKSLGTTSNT LPNVPPAVLV RFLREHRSEW ADFNVDAYSA TALKTNSCAY  480
PGMRPTRFTG SQIIMPLGHT IEHEEMLEVI RLEGHSLGHE NAFISGDIHL LQMCRGIDEN  540
AVGACAELVF APIDEMFPDD APLLPSGFRI IPLDSISNDA QDTLNAQRTL DLTSSLEVGP  600
ATNTAQNASS SSCAARSLLT IAFQFPYEDN LQENVATMAR QYVRSVISSV QRVAMAISPT  660
GLGPTLGPKV SPGSPEALTL AQWINQSYSY HMGAQLLGTD SVGAESVLKN LWHHHDAILC  720
CSIKSLPVFI FANKAGLDML ETTLVALQDI TLDKIFDESG RKALFAELAK IMQQGFAYLA  780
GGICMSAMGR HISYEQAIAW KVVADDESTV HCLAFSFINW SFV

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor involved in the regulation of interfascicular fiber (cortical cells) and secondary xylem differentiation in the inflorescence stems. Required for lateral shoot meristems (LSMs) and flower meristems (FMs) initiation. May be involved in the determination of vascular patterning and organ polarity (PubMed:10559440, PubMed:11169198, PubMed:11402186, PubMed:15111711, PubMed:15598805, PubMed:7555701). Directly regulates the expression of AGO10, ZPR1, ZPR2, ZPR3 and ZPR4 (PubMed:22781836). Required to regulate adaxial-abaxial polarity and leaf axial patterning (PubMed:20807212). {ECO:0000269\|PubMed:10559440, ECO:0000269\|PubMed:11169198, ECO:0000269\|PubMed:11402186, ECO:0000269\|PubMed:15111711, ECO:0000269\|PubMed:15598805, ECO:0000269\|PubMed:20807212, ECO:0000269\|PubMed:22781836, ECO:0000269\|PubMed:7555701}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By auxin. Repressed by ZPR and miR165. Induced by DOF5.1 (PubMed:20807212). {ECO:0000269\|PubMed:15111711, ECO:0000269\|PubMed:17237362, ECO:0000269\|PubMed:20807212}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019178153.1	0.0	PREDICTED: homeobox-leucine zipper protein REVOLUTA-like
Refseq	XP_019178156.1	0.0	PREDICTED: homeobox-leucine zipper protein REVOLUTA-like
Swissprot	Q9SE43	0.0	REV_ARATH; Homeobox-leucine zipper protein REVOLUTA
TrEMBL	D7SKZ0	0.0	D7SKZ0_VITVI; Uncharacterized protein
STRING	VIT_06s0004g02800.t01	0.0	(Vitis vinifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA457	24	140

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G60690.1	0.0	HD-ZIP family protein

Publications ? help Back to Top
Lian H,Li X,Liu Z,He Y HYL1 is required for establishment of stamen architecture with four microsporangia in Arabidopsis. J. Exp. Bot., 2013. 64(11): p. 3397-410 [PMID:23918970] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Baima S, et al. Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module. Mol Plant, 2014. 7(6): p. 1006-1025 [PMID:24777988] Jia X, et al. Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic. Plant Sci., 2015. 233: p. 11-21 [PMID:25711809] Roodbarkelari F,Du F,Truernit E,Laux T ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response. BMC Biol., 2015. 13: p. 74 [PMID:26358077] Shi B, et al. Two-Step Regulation of a Meristematic Cell Population Acting in Shoot Branching in Arabidopsis. PLoS Genet., 2016. 12(7): p. e1006168 [PMID:27398935]