PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Convolvulaceae; Ipomoeeae; Ipomoea

Family

NF-YA

Protein Properties

Length: 447aa MW: 49680.4 Da PI: 8.7995

Description

NF-YA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Itr_sc000843.1_g00006.1	genome	Kazusa	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CBFB_NFYA	94.6	1.2e-29	15	71	1	58
CBFB_NFYA 1 deplYVNaKQyqrIlkRRqkRakleeekkldeksrkpylheSRhkhAlrRpRgsgGrF 58 de ++VNaKQyq+Il+RRq Rakle++++l ++ rkpylheSRh hAl+R+Rg+gGrF Itr_sc000843.1_g00006.1 15 DEHIFVNAKQYQAILRRRQCRAKLEAQNRL-SRVRKPYLHESRHIHALNRARGPGGRF 71 688*************************.************************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00521	9.6E-33	13	74	IPR001289	Nuclear transcription factor Y subunit A
PROSITE profile	PS51152	33.779	14	74	IPR001289	Nuclear transcription factor Y subunit A
PRINTS	PR00616	1.0E-20	17	39	IPR001289	Nuclear transcription factor Y subunit A
Pfam	PF02045	2.1E-25	17	71	IPR001289	Nuclear transcription factor Y subunit A
PROSITE pattern	PS00686	0	19	39	IPR018362	CCAAT-binding factor, conserved site
PRINTS	PR00616	1.0E-20	48	71	IPR001289	Nuclear transcription factor Y subunit A
Pfam	PF12165	1.5E-58	176	329	IPR021998	Alfin
SuperFamily	SSF57903	2.66E-17	382	444	IPR011011	Zinc finger, FYVE/PHD-type
Gene3D	G3DSA:3.30.40.10	7.9E-18	386	444	IPR013083	Zinc finger, RING/FYVE/PHD-type
PROSITE profile	PS50016	9.526	391	443	IPR019787	Zinc finger, PHD-finger
CDD	cd15613	2.64E-32	393	443	No hit	No description
SMART	SM00249	2.1E-9	393	441	IPR001965	Zinc finger, PHD-type
Pfam	PF00628	3.3E-10	394	442	IPR019787	Zinc finger, PHD-finger
PROSITE pattern	PS01359	0	394	440	IPR019786	Zinc finger, PHD-type, conserved site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0016602	Cellular Component	CCAAT-binding factor complex
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0008270	Molecular Function	zinc ion binding
GO:0042393	Molecular Function	histone binding

Sequence ? help Back to Top
Protein Sequence Length: 447 aa Download sequence Send to blast
MTATRLPLPL DLSQDEHIFV NAKQYQAILR RRQCRAKLEA QNRLSRVRKP YLHESRHIHA 60 LNRARGPGGR FLNVKKKAAI SSQLSLCRNA CKLPTVKVFI AGVNSDPVRL QSLWTVIRTT 120 AIVSVLTTTT RSSESHSFAS KQLSIAGEME GAVGVGGGGG GAAAAAAGGG QYNPRTVEEV 180 FKDFKGRRNG LIKALTTDVN DFYQQCDPEK ENLCLYGFPS EQWEVNLPAE EVPPELPEPA 240 LGINFARDGM QEKDWLSLVA VHSDAWLLAV SFYFGSRFGF DKADRVNRKV ISIFLAAIDA 300 KNSGPYSKKL MKRLFNMIND MPTVFEVVTG AAKKQQKEKS SVSNHSSNKT KSNPKPQRAA 360 SESQGRFTKP PPKDEEEGLE EEDEEEEEHG ETLCGACGEN YASDEFWICC DICEKWFHGK 420 CVKITPARAE HIKQYKCPSC SNKRARP

Sequence ? help Back to Top

Protein Sequence Length: 447 aa Download sequence Send to blast

MTATRLPLPL DLSQDEHIFV NAKQYQAILR RRQCRAKLEA QNRLSRVRKP YLHESRHIHA  60
LNRARGPGGR FLNVKKKAAI SSQLSLCRNA CKLPTVKVFI AGVNSDPVRL QSLWTVIRTT  120
AIVSVLTTTT RSSESHSFAS KQLSIAGEME GAVGVGGGGG GAAAAAAGGG QYNPRTVEEV  180
FKDFKGRRNG LIKALTTDVN DFYQQCDPEK ENLCLYGFPS EQWEVNLPAE EVPPELPEPA  240
LGINFARDGM QEKDWLSLVA VHSDAWLLAV SFYFGSRFGF DKADRVNRKV ISIFLAAIDA  300
KNSGPYSKKL MKRLFNMIND MPTVFEVVTG AAKKQQKEKS SVSNHSSNKT KSNPKPQRAA  360
SESQGRFTKP PPKDEEEGLE EEDEEEEEHG ETLCGACGEN YASDEFWICC DICEKWFHGK  420
CVKITPARAE HIKQYKCPSC SNKRARP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5xvj_A	1e-61	173	332	2	135	PHD finger protein ALFIN-LIKE 7
5xvj_B	1e-61	173	332	2	135	PHD finger protein ALFIN-LIKE 7
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. {ECO:0000250}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006371893.1	1e-140	PHD finger protein ALFIN-LIKE 4 isoform X1
Refseq	XP_011011112.1	1e-140	PREDICTED: PHD finger protein ALFIN-LIKE 4-like isoform X1
Refseq	XP_019193265.1	1e-140	PREDICTED: PHD finger protein ALFIN-LIKE 4-like isoform X1
Swissprot	Q5XEM9	1e-119	ALFL5_ARATH; PHD finger protein ALFIN-LIKE 5
TrEMBL	U5FFQ7	1e-139	U5FFQ7_POPTR; Uncharacterized protein
STRING	XP_010091959.1	1e-138	(Morus notabilis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA184	5	6

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G14020.1	2e-32	nuclear factor Y, subunit A6

Publications ? help Back to Top
Lee WY,Lee D,Chung WI,Kwon CS Arabidopsis ING and Alfin1-like protein families localize to the nucleus and bind to H3K4me3/2 via plant homeodomain fingers. Plant J., 2009. 58(3): p. 511-24 [PMID:19154204] Wei W, et al. The Alfin-like homeodomain finger protein AL5 suppresses multiple negative factors to confer abiotic stress tolerance in Arabidopsis. Plant J., 2015. 81(6): p. 871-83 [PMID:25619813]