PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Itr_sc000495.1_g00005.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Convolvulaceae; Ipomoeeae; Ipomoea
Family GRAS
Protein Properties Length: 519aa    MW: 56465 Da    PI: 5.3861
Description GRAS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Itr_sc000495.1_g00005.1genomeKazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1GRAS414.31.1e-1261525151374
                     GRAS   1 lvelLlecAeavssgdlelaqalLarlsel..aspdgdpmqRlaayfteALaarlarsvselykalppsetseknsseelaalklf 84 
                              lv++L++cA  v+ g+++la +l+ +l+ l  + ++g  + ++a yf  AL++rl+   ++ ++ +    +      e    ++ f
  Itr_sc000495.1_g00005.1 152 LVHALMTCAVSVQRGEFSLAGSLIDELQLLltRVNSGCGIGKVAGYFIDALSKRLYT--PQGVSLM---GS----AYEDEILYSHF 228
                              689*************************9987889999******************9..3333222...22....3344456789* PP

                     GRAS  85 sevsPilkfshltaNqaIleavegeervHiiDfdisqGlQWpaLlqaLasRpegppslRiTgvgspesgskeeleetgerLakfAe 170
                              +e+ P+lkf+h+taNqaIlea++g+++vH+iDf++++GlQWpaL+qaLa Rp+gpp lR+Tg+g+p+++ +++l+e+g +La++A+
  Itr_sc000495.1_g00005.1 229 YEAAPYLKFAHFTANQAILEAFHGHDCVHVIDFNLMHGLQWPALIQALALRPGGPPLLRLTGIGPPSPDGRDSLREIGLKLAELAR 314
                              ************************************************************************************** PP

                     GRAS 171 elgvpfefnvlvakrledleleeLrvkpgEalaVnlvlqlhrlldesvsleserdevLklvkslsPkvvvvveqeadhnsesFler 256
                              +++v+f f+ ++a+rl+d++ ++L+v ++Ea+aVn+++qlh+ll  +    s++d+vL  ++sl+Pkvv+vveqea+hn+++Fl+r
  Itr_sc000495.1_g00005.1 315 SVNVRFAFRGVAASRLDDVKSWMLQVGSNEAVAVNSIMQLHKLLGPDPIRGSPIDTVLGWIRSLNPKVVTVVEQEANHNQPEFLDR 400
                              ********************************************99999999********************************** PP

                     GRAS 257 flealeyysalfdsleaklpreseerikvErellgreivnvvacegaerrerhetlekWrerleeaGFkpvplsekaakqaklllr 342
                              f+e+l+yys++fdslea     ++ ++ + +++++rei+nvv+ceg +r+erhe l+kW++rl+ aGFkp++l+++a kqa++ll 
  Itr_sc000495.1_g00005.1 401 FTESLYYYSTMFDSLEAC---PAQPEKALAEMYIQREICNVVCCEGVARVERHEPLGKWKARLTGAGFKPLNLGSNAFKQASMLLT 483
                              ****************99...566677788888***************************************************** PP

                     GRAS 343 kvksdgyrveeesgslvlgWkdrpLvsvSaWr 374
                               ++ +gy+vee +g+l+lgW++rpL+++SaW+
  Itr_sc000495.1_g00005.1 484 LFSAEGYNVEETEGCLTLGWHSRPLIAASAWQ 515
                              *******************************6 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM011295.5E-1628103No hitNo description
PfamPF120414.7E-262897IPR021914Transcriptional factor DELLA, N-terminal
PROSITE profilePS5098562.142126495IPR005202Transcription factor GRAS
PfamPF035143.8E-124152515IPR005202Transcription factor GRAS
Sequence ? help Back to Top
Protein Sequence    Length: 519 aa     Download sequence    Send to blast
MSPHDSSITS SSGSSSSSCS AAHVDQIDSL LAGAGYMVRS SDLRHVAQRL EHLESFMVNS  60
PMGSEISQHL GNDVVHQNPS DLGSWVDSLL SELHPPPVPE FAAPCPSDSN YVAAGPTGWS  120
ECEAMQQQPQ IVSPSHLTVV TATEQEDSGI RLVHALMTCA VSVQRGEFSL AGSLIDELQL  180
LLTRVNSGCG IGKVAGYFID ALSKRLYTPQ GVSLMGSAYE DEILYSHFYE AAPYLKFAHF  240
TANQAILEAF HGHDCVHVID FNLMHGLQWP ALIQALALRP GGPPLLRLTG IGPPSPDGRD  300
SLREIGLKLA ELARSVNVRF AFRGVAASRL DDVKSWMLQV GSNEAVAVNS IMQLHKLLGP  360
DPIRGSPIDT VLGWIRSLNP KVVTVVEQEA NHNQPEFLDR FTESLYYYST MFDSLEACPA  420
QPEKALAEMY IQREICNVVC CEGVARVERH EPLGKWKARL TGAGFKPLNL GSNAFKQASM  480
LLTLFSAEGY NVEETEGCLT LGWHSRPLIA ASAWQASRD
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3g_A3e-601405147378Protein SCARECROW
5b3h_A3e-601405146377Protein SCARECROW
5b3h_D3e-601405146377Protein SCARECROW
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Transcription coactivator of the zinc finger transcription factors GAF1/IDD2 and ENY/IDD1 in regulation of gibberellin homeostasis and signaling (PubMed:25035403). No effect of the BOI proteins on its stability. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Positively regulates XERICO expression. In contrast to RGA, it is less sensitive to GA. Its activity is probably regulated by other phytohormones such as auxin and ethylene. {ECO:0000269|PubMed:11487693, ECO:0000269|PubMed:11606551, ECO:0000269|PubMed:11606552, ECO:0000269|PubMed:14973286, ECO:0000269|PubMed:15128937, ECO:0000269|PubMed:16034591, ECO:0000269|PubMed:17933900, ECO:0000269|PubMed:25035403, ECO:0000269|PubMed:9389651}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_019192394.10.0PREDICTED: DELLA protein DWARF8-like
SwissprotQ9LQT81e-161GAI_ARATH; DELLA protein GAI
TrEMBLA0A328CVB60.0A0A328CVB6_9ASTE; Uncharacterized protein
TrEMBLA0A484NC120.0A0A484NC12_9ASTE; Uncharacterized protein
STRINGXP_010249953.10.0(Nelumbo nucifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA1514158
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G14920.11e-138GRAS family protein
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Gallego-Giraldo C, et al.
    Role of the gibberellin receptors GID1 during fruit-set in Arabidopsis.
    Plant J., 2014. 79(6): p. 1020-1032
    [PMID:24961590]
  4. Fukazawa J, et al.
    DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis.
    Plant Cell, 2014. 26(7): p. 2920-38
    [PMID:25035403]
  5. Marín-de la Rosa N, et al.
    Genome Wide Binding Site Analysis Reveals Transcriptional Coactivation of Cytokinin-Responsive Genes by DELLA Proteins.
    PLoS Genet., 2015. 11(7): p. e1005337
    [PMID:26134422]
  6. Shi H,Wei Y,Wang Q,Reiter RJ,He C
    Melatonin mediates the stabilization of DELLA proteins to repress the floral transition in Arabidopsis.
    J. Pineal Res., 2016. 60(3): p. 373-9
    [PMID:26887824]
  7. Lee SA, et al.
    Interplay between ABA and GA Modulates the Timing of Asymmetric Cell Divisions in the Arabidopsis Root Ground Tissue.
    Mol Plant, 2016. 9(6): p. 870-84
    [PMID:26970019]
  8. Qu J,Kang SG,Hah C,Jang JC
    Molecular and cellular characterization of GA-Stimulated Transcripts GASA4 and GASA6 in Arabidopsis thaliana.
    Plant Sci., 2016. 246: p. 1-10
    [PMID:26993231]
  9. Shahnejat-Bushehri S,Nobmann B,Devi Allu A,Balazadeh S
    JUB1 suppresses Pseudomonas syringae-induced defense responses through accumulation of DELLA proteins.
    Plant Signal Behav, 2016. 11(6): p. e1181245
    [PMID:27159137]
  10. Shahnejat-Bushehri S,Tarkowska D,Sakuraba Y,Balazadeh S
    Arabidopsis NAC transcription factor JUB1 regulates GA/BR metabolism and signalling.
    Nat Plants, 2016. 2: p. 16013
    [PMID:27249348]
  11. Wang H, et al.
    The DELLA-CONSTANS Transcription Factor Cascade Integrates Gibberellic Acid and Photoperiod Signaling to Regulate Flowering.
    Plant Physiol., 2016. 172(1): p. 479-88
    [PMID:27406167]
  12. Li W,Wang H,Yu D
    Arabidopsis WRKY Transcription Factors WRKY12 and WRKY13 Oppositely Regulate Flowering under Short-Day Conditions.
    Mol Plant, 2016. 9(11): p. 1492-1503
    [PMID:27592586]
  13. Liu B,De Storme N,Geelen D
    Gibberellin Induces Diploid Pollen Formation by Interfering with Meiotic Cytokinesis.
    Plant Physiol., 2017. 173(1): p. 338-353
    [PMID:27621423]
  14. Matsuoka K, et al.
    Differential Cellular Control by Cotyledon-Derived Phytohormones Involved in Graft Reunion of Arabidopsis Hypocotyls.
    Plant Cell Physiol., 2016. 57(12): p. 2620-2631
    [PMID:27986917]
  15. Zentella R, et al.
    The Arabidopsis O-fucosyltransferase SPINDLY activates nuclear growth repressor DELLA.
    Nat. Chem. Biol., 2017. 13(5): p. 479-485
    [PMID:28244988]
  16. Zhang Y, et al.
    GA-DELLA pathway is involved in regulation of nitrogen deficiency-induced anthocyanin accumulation.
    Plant Cell Rep., 2017. 36(4): p. 557-569
    [PMID:28275852]
  17. Zhang L,Chen L,Yu D
    Transcription Factor WRKY75 Interacts with DELLA Proteins to Affect Flowering.
    Plant Physiol., 2018. 176(1): p. 790-803
    [PMID:29133369]
  18. Nelson SK,Ariizumi T,Steber CM
    Biology in the Dry Seed: Transcriptome Changes Associated with Dry Seed Dormancy and Dormancy Loss in the Arabidopsis GA-Insensitive sleepy1-2 Mutant.
    Front Plant Sci, 2017. 8: p. 2158
    [PMID:29312402]
  19. Liu B,De Storme N,Geelen D
    Cold-Induced Male Meiotic Restitution in Arabidopsis thaliana Is Not Mediated by GA-DELLA Signaling.
    Front Plant Sci, 2018. 9: p. 91
    [PMID:29459879]
  20. Zhang Y, et al.
    DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6.
    Plant Cell Rep., 2018. 37(7): p. 981-992
    [PMID:29574486]
  21. Felipo-Benavent A, et al.
    Regulation of xylem fiber differentiation by gibberellins through DELLA-KNAT1 interaction.
    Development, 2019.
    [PMID:30389856]
  22. Wright DA, et al.
    Recovery of YAC-end sequences through complementation of an Escherichia coli pyrF mutation.
    Nucleic Acids Res., 1997. 25(13): p. 2679-80
    [PMID:9185581]