PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Heliantheae alliance; Heliantheae; Helianthus

Family

bZIP

Protein Properties

Length: 285aa MW: 31657.7 Da PI: 7.3252

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Han#S48334826	PU_unref	Unigene	View CDS
PUT-169a-Helianthus_annuus-3516	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	30.6	7.6e-10	191	249	5	63
CHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 5 krerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklksev 63 kr++r NR +A rs +RK ++ eLe+kvk+L++e ++L ++ +l+ e + ++e+ Han001789 191 KRAKRILANRQSAARSKERKMRYTSELEKKVKTLQTEATTLSAQVTKLQRETSDITTEN 249 9***********************************************99988777665 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00338	2.7E-15	187	251	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	11.427	189	252	IPR004827	Basic-leucine zipper domain
Gene3D	G3DSA:1.20.5.170	5.9E-12	191	244	No hit	No description
Pfam	PF00170	9.3E-9	191	245	IPR004827	Basic-leucine zipper domain
SuperFamily	SSF57959	8.44E-11	191	242	No hit	No description
CDD	cd14703	6.81E-23	192	241	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 285 aa Download sequence Send to blast
RGPLVNRNNP FPALLTPGVA MDPKFAGKPL PVTQYHSGDR KHLDRMSETP TRPPHHRRTQ 60 SETFLPFADE DILLDDVVAD FNFASIDLPT LSGDPPAPTS TENSSEREPA DRKPVGYGNH 120 LRSLSMDSDF FDELGFGSAA GDGGSRHRHS NSMDGSAATS FEGDSVLMLV DNSKKALAPD 180 KLAELSLIDP KRAKRILANR QSAARSKERK MRYTSELEKK VKTLQTEATT LSAQVTKLQR 240 ETSDITTENX ELRLRLESMX AHAQLRDALN EALKEEISRL NVRRX

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Mostly expressed in dividing cells, present in leaves, roots and seedlings. {ECO:0000269\|PubMed:15108305, ECO:0000269\|PubMed:15824315}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds specifically to the VIP1 response elements (VREs) DNA sequence 5'-ACNGCT-3' found in some stress genes (e.g. TRX8 and MYB44), when phosphorylated/activated by MPK3. Required for Agrobacterium VirE2 nuclear import and tumorigenicity. Promotes transient expression of T-DNA in early stages by interacting with VirE2 in complex with the T-DNA and facilitating its translocation to the nucleus, and mediates stable genetic transformation by Agrobacterium by binding H2A histone. Prevents cell differentiation and shoot formation. Limits sulfate utilization efficiency (SUE) and sulfate uptake, especially in low-sulfur conditions. {ECO:0000269\|PubMed:11432846, ECO:0000269\|PubMed:12124400, ECO:0000269\|PubMed:15108305, ECO:0000269\|PubMed:15824315, ECO:0000269\|PubMed:17947581, ECO:0000269\|PubMed:19820165, ECO:0000269\|PubMed:20547563}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Transcriptionally activated during the acquisition of pluripotentiality (in protoplasts) by pericentromeric chromatin decondensation and DNA demethylation. Targeted to degradation by the proteasome by VBF and Agrobacterium virF in SCF(VBF) and SCF(virF) E3 ubiquitin ligase complexes after mediating T-DNA translocation to the nucleus. {ECO:0000269\|PubMed:15108305}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_022034700.1	0.0	transcription factor VIP1-like
Swissprot	Q9MA75	5e-62	VIP1_ARATH; Transcription factor VIP1
TrEMBL	A0A251UYN0	0.0	A0A251UYN0_HELAN; Putative basic-leucine zipper domain-containing protein
STRING	XP_004516647.1	2e-81	(Cicer arietinum)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G43700.1	2e-64	VIRE2-interacting protein 1

Publications ? help Back to Top
Wang Y, et al. The putative Agrobacterium transcriptional activator-like virulence protein VirD5 may target T-complex to prevent the degradation of coat proteins in the plant cell nucleus. New Phytol., 2014. 203(4): p. 1266-81 [PMID:24865527] Xu DB, et al. A G-protein β subunit, AGB1, negatively regulates the ABA response and drought tolerance by down-regulating AtMPK6-related pathway in Arabidopsis. PLoS ONE, 2015. 10(1): p. e0116385 [PMID:25635681] Chen J, et al. ZmbZIP91 regulates expression of starch synthesis-related genes by binding to ACTCAT elements in their promoters. J. Exp. Bot., 2016. 67(5): p. 1327-38 [PMID:26689855] Tsugama D,Liu S,Takano T VIP1 is very important/interesting protein 1 regulating touch responses of Arabidopsis. Plant Signal Behav, 2016. 11(6): p. e1187358 [PMID:27171129] Tsugama D,Liu S,Takano T The bZIP Protein VIP1 Is Involved in Touch Responses in Arabidopsis Roots. Plant Physiol., 2016. 171(2): p. 1355-65 [PMID:27208231] Takeo K,Ito T Subcellular localization of VIP1 is regulated by phosphorylation and 14-3-3 proteins. FEBS Lett., 2017. 591(13): p. 1972-1981 [PMID:28542772] Wang L,Lacroix B,Guo J,Citovsky V The Agrobacterium VirE2 effector interacts with multiple members of the Arabidopsis VIP1 protein family. Mol. Plant Pathol., 2018. 19(5): p. 1172-1183 [PMID:28802023]