PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus

Family

bHLH

Protein Properties

Length: 248aa MW: 28018.8 Da PI: 4.8418

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
HL.SW.v1.0.G042452.1	genome	HOPBASE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	51.1	2.4e-16	33	82	2	55
HHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 2 rrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 r +h+e E+rRR++iN++f+ Lrel+P++ ++K +Ka+ L + +eY+++Lq HL.SW.v1.0.G042452.1 33 RSKHSETEQRRRSKINERFQILRELIPQS----DQKRDKASFLLELIEYVQYLQ 82 899***********************9....9*****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	1.18E-18	28	102	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	2.6E-22	28	105	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.95E-15	29	85	No hit	No description
PROSITE profile	PS50888	16.406	31	81	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.8E-14	33	82	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	3.6E-10	37	87	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 248 aa Download sequence Send to blast
MVESSRGHQE EFEDEEEVTH KGKVDGKSRE KNRSKHSETE QRRRSKINER FQILRELIPQ 60 SDQKRDKASF LLELIEYVQY LQEKINMYEE SYQGWSSEPA KLHPWRNQHA SAETFADLSQ 120 VVKNGSDLQN NVIVSPSLLP NQQNSLESDM GVAMVYKTLD HLPGSATQSV PPNVEQTNMF 180 DPSGRHVVPL QPMQESVSDD SDVDPLPQPL PEPWQGGHTT TSSVLNNAPS IKEDKSGSLT 240 MSNSYSQG

Functional Description ? help Back to Top
Source	Description
UniProt	Positive brassinosteroid-signaling protein.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by heat treatment. {ECO:0000269\|PubMed:12679534}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024023288.1	1e-120	LOW QUALITY PROTEIN: transcription factor BIM3
Swissprot	Q9CAA4	1e-41	BIM2_ARATH; Transcription factor BIM2
TrEMBL	A0A2P5E9A7	1e-144	A0A2P5E9A7_TREOI; Basic helix-loop-helix transcription factor
STRING	XP_009373761.1	9e-96	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1730	33	82

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G69010.1	3e-44	BES1-interacting Myc-like protein 2

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281]