PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G038993.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family HD-ZIP
Protein Properties Length: 871aa    MW: 95498.1 Da    PI: 5.6704
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G038993.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox58.98.5e-1951109357
                           --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
              Homeobox   3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57 
                           k  ++t+eq+e+Le+l++ +++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  HL.SW.v1.0.G038993.1  51 KYVRYTPEQVEALERLYHDCPKPSSMRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 109
                           5679*****************************************************97 PP
2START181.16.5e-571954032205
                           HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT.. CS
                 START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg.. 88 
                           +aee+++e+++ka+ ++  Wv+++ +++g++++ +++ s+++sg a+ra+g+v  +++  v+e+l+d++ W ++++++++++++s+g  
  HL.SW.v1.0.G038993.1 195 IAEETLAEFLSKATGTAVEWVQMPGMKPGPDSIGIVAISHGCSGVAARACGLVGLEPT-RVAEILKDRPSWFRDCRAVDVINALSTGng 282
                           7899******************************************************.8888888888******************** PP

                           EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE-- CS
                 START  89 galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlk 173
                           g+++l +++l+a+++l+p Rdf+ +Ry+  l++g++v++++S++++q+ p+    +++vRae+lpSg+li+p+++g+s +++v+h+dl+
  HL.SW.v1.0.G038993.1 283 GTIELLYMQLYAPTTLAPaRDFWLLRYTSVLEDGSLVVCERSLNNTQNGPSmpvVQNFVRAETLPSGYLIRPCEGGGSIIHVVDHMDLE 371
                           **************************************************999999********************************* PP

                           SSXXHHHHHHHHHHHHHHHHHHHHHHTXXXXX CS
                 START 174 grlphwllrslvksglaegaktwvatlqrqce 205
                            ++++++lr+l++s++  ++kt++a+l+++++
  HL.SW.v1.0.G038993.1 372 PWSVPEVLRPLYESSTLLAQKTTMAALRHLRQ 403
                           ***************************99876 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.72646110IPR001356Homeobox domain
SMARTSM003895.2E-1648114IPR001356Homeobox domain
SuperFamilySSF466898.55E-1750114IPR009057Homeodomain-like
CDDcd000868.48E-1751111No hitNo description
PfamPF000462.3E-1652109IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.602.2E-1853109IPR009057Homeodomain-like
CDDcd146861.20E-6103142No hitNo description
PROSITE profilePS5084826.417185413IPR002913START domain
CDDcd088752.71E-79189404No hitNo description
SMARTSM002342.2E-43194404IPR002913START domain
Gene3DG3DSA:3.30.530.206.5E-23194400IPR023393START-like domain
SuperFamilySSF559611.79E-38194406No hitNo description
PfamPF018521.7E-54195403IPR002913START domain
PfamPF086704.6E-52729869IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010067Biological Processprocambium histogenesis
GO:0010072Biological Processprimary shoot apical meristem specification
GO:0010089Biological Processxylem development
GO:0045597Biological Processpositive regulation of cell differentiation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 871 aa     Download sequence    Send to blast
MLCITIPSDI YSVQEIESSS ISKGEDLWGR SMMAVTSSCK DGTKIAMDNG KYVRYTPEQV  60
EALERLYHDC PKPSSMRRQQ LIRECPILSN IEPKQIKVWF QNRRCREKQR KEASRLQAVN  120
RKLTAMNKLL MEENDRLQKQ VSQLVYENSY FRQQTQNATL ATTDTSCESV VTSGQHHLTP  180
QHPPRDASPA GLLSIAEETL AEFLSKATGT AVEWVQMPGM KPGPDSIGIV AISHGCSGVA  240
ARACGLVGLE PTRVAEILKD RPSWFRDCRA VDVINALSTG NGGTIELLYM QLYAPTTLAP  300
ARDFWLLRYT SVLEDGSLVV CERSLNNTQN GPSMPVVQNF VRAETLPSGY LIRPCEGGGS  360
IIHVVDHMDL EPWSVPEVLR PLYESSTLLA QKTTMAALRH LRQISQELSQ PNATGWGKRP  420
AALRALSQKL SKGFNEAVNG FTDEGWSMLE SDGIDDVTLL VNSSPSKIMG ANISYANGFP  480
SASNSVLCAK ASMLLQNVPP AILLRFLREH RSEWADSSID AYSAAAIKAG PCSLPGTRAG  540
SFGGQVILPL AHTIEHEEFM EVIKLENMGH YRDDMIMPVD IFLLQLCSGV DENAVGNCAE  600
LVFAPIDASF SDDAPILPSG FRIIPLDSGT DSPSPNRTLD LASALEVGPT GNRASGDNAG  660
NSGNRKSVMT IAFQFAFEMH LQESVAAMAR QYVRSIIASV QRVALALSPS RLGSHTGLRP  720
PPGTPEAQTL STWISQSYRC YLGVELLKNE GSESILKSLW QHSDAVLCCS LKAMPVFTFA  780
NQAGLDMLET TIVALQDITL EKIFDDNGRK TLCSEFPQIM QQGFMCLQGG ICMSSMGRPV  840
SYERAVAWKV LDEEENAHCI CFMFINWSFV *
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of vascular development. May promote differentiation of precambial and cambial cells. {ECO:0000269|PubMed:11402194, ECO:0000269|PubMed:15598805}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by miR165. {ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:8575317}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010102406.20.0homeobox-leucine zipper protein ATHB-8
SwissprotQ391230.0ATHB8_ARATH; Homeobox-leucine zipper protein ATHB-8
TrEMBLA0A2P5BF580.0A0A2P5BF58_TREOI; Octamer-binding transcription factor
STRINGXP_010102406.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19463387
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G32880.10.0homeobox gene 8
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Hategan L,Godza B,Kozma-Bognar L,Bishop GJ,Szekeres M
    Differential expression of the brassinosteroid receptor-encoding BRI1 gene in Arabidopsis.
    Planta, 2014. 239(5): p. 989-1001
    [PMID:24488524]
  3. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  4. Kakehi J, et al.
    Mutations in ribosomal proteins, RPL4 and RACK1, suppress the phenotype of a thermospermine-deficient mutant of Arabidopsis thaliana.
    PLoS ONE, 2015. 10(1): p. e0117309
    [PMID:25625317]
  5. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  6. Liu S, et al.
    Expression of wild-type PtrIAA14.1, a poplar Aux/IAA gene causes morphological changes in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 388
    [PMID:26082787]
  7. Yamaguchi YL, et al.
    Root-Knot and Cyst Nematodes Activate Procambium-Associated Genes in Arabidopsis Roots.
    Front Plant Sci, 2017. 8: p. 1195
    [PMID:28747918]
  8. Yamazaki K, et al.
    Suppression of DELLA signaling induces procambial cell formation in culture.
    Plant J., 2018. 94(1): p. 48-59
    [PMID:29383774]