PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G036749.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family ARF
Protein Properties Length: 694aa    MW: 76858.5 Da    PI: 6.302
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G036749.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B373.23.1e-23127227198
                           EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEE CS
                    B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvF 82 
                           f+k+lt sd++++g +++ +k+a+e+       +   + +++l  +d++g +W++k+i+r++++r++lt+GW+ Fv +++L +gD +vF
  HL.SW.v1.0.G036749.1 127 FCKILTASDTSTHGGFSVLRKHATEClppldmtQ--ATPTQELAAKDLHGYEWKFKHIFRGQPRRHLLTTGWSTFVTSKRLVAGDAFVF 213
                           99****************************9543..445569*********************************************** PP

                           EE-SSSEE..EEEEE- CS
                    B3  83 kldgrsefelvvkvfr 98 
                              + +++el+v+v+r
  HL.SW.v1.0.G036749.1 214 L--RGDNGELRVGVRR 227
                           *..3489999****98 PP
2Auxin_resp101.89e-34253332183
            Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                           a+ha++t++ F v+Y+Pr+  s+F++ ++k+++a+++k++vGmRfkm+fe+eds+err++Gt+vgv d+++ +W++S WrsLk
  HL.SW.v1.0.G036749.1 253 ASHAFNTRTLFVVYYKPRT--SQFIIGLNKYLDAMNNKLTVGMRFKMRFEGEDSPERRFTGTIVGVGDVSS-QWTDSTWRSLK 332
                           689***************6..9**********************************************888.*********96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019361.96E-40115256IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.105.7E-40120242IPR015300DNA-binding pseudobarrel domain
CDDcd100171.14E-19125227No hitNo description
PfamPF023623.7E-21127227IPR003340B3 DNA binding domain
SMARTSM010199.9E-22127229IPR003340B3 DNA binding domain
PROSITE profilePS5086311.97127229IPR003340B3 DNA binding domain
PfamPF065071.1E-31253332IPR010525Auxin response factor
PfamPF023094.4E-7561615IPR033389AUX/IAA domain
SuperFamilySSF542771.7E-10572655No hitNo description
PROSITE profilePS5174523.518579671IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 694 aa     Download sequence    Send to blast
MAHLEDGSSV SRAETGPENS ILFNELWNAC AGPLVEVPRP GERVFYFPQG HMEQLEASTN  60
QEVNHQLPLF NLPSKIFCSV LNIEYLAEQE TDEVYARITL VPEDDQTEPT SPDPCLDEPV  120
RPNVHSFCKI LTASDTSTHG GFSVLRKHAT ECLPPLDMTQ ATPTQELAAK DLHGYEWKFK  180
HIFRGQPRRH LLTTGWSTFV TSKRLVAGDA FVFLRGDNGE LRVGVRRLAC QQSLMPSSVI  240
SSHSMHLGVL ATASHAFNTR TLFVVYYKPR TSQFIIGLNK YLDAMNNKLT VGMRFKMRFE  300
GEDSPERRFT GTIVGVGDVS SQWTDSTWRS LKIQWDEHAT IPRPERVSPW EIEPFVASSA  360
SLNLPQPAAK NKRPRPVDIP RSEITTNSAA SAFWYQGSTQ SPELTQLGSA AEVQSSDSQA  420
VWPLMHKDTS KGNYYGSMVR FEGIWPSPHV DISLNLFSDS TGDTKTVSAR SVLSSCASTI  480
SSRVSNQSEK AAKFDASVGC RLFGINLTCN SPIPSHLEKE SPSLVAVSSS DKGFAPAAVS  540
EADKVHNQVI TNLAKDQKVI SESPQKDTQS KHSSLSSRSR TKKVQMQGVA VGRAIDLTTL  600
SGYDDLIDEL EKMFEIKGEL RPPSKWAVVF TDDENDMMLV GDDLWTDFCK MVKKIFIYSS  660
EEVKKMSNFK LRASSIEGEG TTASLDSDHR AET*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A1e-1752236219362Auxin response factor 1
4ldw_A1e-1752236219362Auxin response factor 1
4ldw_B1e-1752236219362Auxin response factor 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1371375KRPRP
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. {ECO:0000269|PubMed:12036261}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015888765.10.0auxin response factor 18 isoform X2
SwissprotQ9C5W90.0ARFR_ARATH; Auxin response factor 18
TrEMBLA0A2P5FHL90.0A0A2P5FHL9_TREOI; Auxin response factor
STRINGXP_010100721.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF15113396
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G61830.10.0auxin response factor 18
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]