PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus

Family

HD-ZIP

Protein Properties

Length: 278aa MW: 31496.7 Da PI: 5.1249

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
HL.SW.v1.0.G033638.1	genome	HOPBASE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	59.7	4.7e-19	59	113	2	56
T--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 2 rkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 ++++f++eq++ Le++Fe++ + +++ +LA++lgL+ rqV +WFqN+Ra++k HL.SW.v1.0.G033638.1 59 NNKRRFSDEQIKSLESMFESETRLEPRKKLQLASELGLQPRQVAIWFQNKRARWK 113 67889*************************************************9 PP
2	HD-ZIP_I/II	117.4	8.1e-38	60	151	2	93
HD-ZIP_I/II 2 kkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLree 90 +krr+s+eq+k+LE++Fe+e++Lep++K +la+eLglqprqva+WFqn+RAR+k+kqlE+dy+ L ++y++l+++ ++L+ke++ L+ + HL.SW.v1.0.G033638.1 60 NKRRFSDEQIKSLESMFESETRLEPRKKLQLASELGLQPRQVAIWFQNKRARWKSKQLERDYSILLSNYKNLASRFDALKKEKQGLALQ 148 79************************************************************************************999 PP HD-ZIP_I/II 91 lke 93 l++ HL.SW.v1.0.G033638.1 149 LQK 151 986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	6.84E-20	35	117	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	5.9E-20	52	114	IPR009057	Homeodomain-like
PROSITE profile	PS50071	18.301	55	115	IPR001356	Homeobox domain
SMART	SM00389	5.7E-17	57	119	IPR001356	Homeobox domain
Pfam	PF00046	1.6E-16	58	113	IPR001356	Homeobox domain
CDD	cd00086	7.63E-15	58	116	No hit	No description
PRINTS	PR00031	1.3E-5	86	95	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	90	113	IPR017970	Homeobox, conserved site
PRINTS	PR00031	1.3E-5	95	111	IPR000047	Helix-turn-helix motif
Pfam	PF02183	7.2E-14	115	155	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009414	Biological Process	response to water deprivation
GO:0009738	Biological Process	abscisic acid-activated signaling pathway
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 278 aa Download sequence Send to blast
MFEDQNNIHG EYSYCPTSES IDHSNNINIH DSSFSNSSST SSSGAGVLVL GSRKKKSRNN 60 KRRFSDEQIK SLESMFESET RLEPRKKLQL ASELGLQPRQ VAIWFQNKRA RWKSKQLERD 120 YSILLSNYKN LASRFDALKK EKQGLALQLQ KLNGDLMQSS KDHNLHKDNN EKDSDNGKMK 180 TESESEVKPS LSSLERSEHV LGVLSDDDSS MKAVYNFEQV LEHEEAELLS MNMNLAPEPP 240 AAAADSSLTS PEDWGSLNSE TLFDESTSGY QWWDFWS*

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription activator that may act as growth regulators in response to water deficit. {ECO:0000269\|PubMed:15604708, ECO:0000269\|PubMed:8771791}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00320	DAP	Transfer from AT2G46680	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By water deficit, by abscisic acid (ABA) and by salt stress. {ECO:0000269\|PubMed:16055682, ECO:0000269\|PubMed:8771791}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_022757591.1	2e-83	homeobox-leucine zipper protein ATHB-12-like
Swissprot	P46897	1e-55	ATHB7_ARATH; Homeobox-leucine zipper protein ATHB-7
TrEMBL	A0A2P5FIG7	1e-122	A0A2P5FIG7_TREOI; Octamer-binding transcription factor
STRING	GLYMA16G02390.1	7e-81	(Glycine max)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF5635	34	52

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G46680.1	1e-52	homeobox 7

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zhou SF, et al. Membrane-associated transcription factor peptidase, site-2 protease, antagonizes ABA signaling in Arabidopsis. New Phytol., 2015. 208(1): p. 188-97 [PMID:25919792]