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Plant Transcription
Factor Database
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Transcription Factor Information
Basic
Information? help
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TF ID |
HL.SW.v1.0.G029763.1 |
Organism |
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Taxonomic ID |
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Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
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Family |
bHLH |
Protein Properties |
Length: 347aa MW: 38805.5 Da PI: 4.5506 |
Description |
bHLH family protein |
Gene Model |
Gene Model ID |
Type |
Source |
Coding Sequence |
HL.SW.v1.0.G029763.1 | genome | HOPBASE | View CDS |
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Signature Domain? help Back to Top |
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No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
1 | HLH | 33.6 | 7.2e-11 | 159 | 202 | 7 | 55 |
HHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
HLH 7 erErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55
+ ErrRR r+++++ Lr+l+P+ +K++Ka+i+ Av Y+++Lq
HL.SW.v1.0.G029763.1 159 ISERRRRGRMKEKLYALRSLVPNI-----TKMDKASIVGDAVLYVQDLQ 202
67*********************7.....7******************9 PP
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Gene Ontology ? help Back to Top |
GO Term |
GO Category |
GO Description |
GO:0034756 | Biological Process | regulation of iron ion transport |
GO:0071281 | Biological Process | cellular response to iron ion |
GO:0071369 | Biological Process | cellular response to ethylene stimulus |
GO:0071732 | Biological Process | cellular response to nitric oxide |
GO:0046983 | Molecular Function | protein dimerization activity |
Sequence ? help Back to Top |
Protein Sequence Length: 347 aa
Download sequence Send
to blast |
MMDNINDFEL HDFIADSNFD QLIDLIRGEN EDPLVNFGCD DLINGSNNFV HATINHHDHP 60 FLGVDRPLNV ATDNNNHVFG FNATPMVSSD PNSLSFIDTV MPEYFDGEIL NMDMVDKGDG 120 DDDDEEDDGD DSSGTTTTTT TTPNASSKRP KVDRSRTLIS ERRRRGRMKE KLYALRSLVP 180 NITKMDKASI VGDAVLYVQD LQTQSKKLKA EIASLEASLE EVERYQGSTT ENSKKIKDVK 240 TNGSLAKMKI ITQMDMFQVE ERGFYVKVVC NKGERAGISL YKALESLTNF NIQSSNLATV 300 SDTFVLTFTL KVLKECDQRE PINLPNLKLW VTGAFINQGF ELKTAF*
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3D Structure ? help Back to Top |
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PDB ID |
Evalue |
Query Start |
Query End |
Hit Start |
Hit End |
Description |
5gnj_A | 3e-13 | 160 | 223 | 12 | 75 | Transcription factor MYC2 |
5gnj_B | 3e-13 | 160 | 223 | 12 | 75 | Transcription factor MYC2 |
5gnj_E | 3e-13 | 160 | 223 | 12 | 75 | Transcription factor MYC2 |
5gnj_F | 3e-13 | 160 | 223 | 12 | 75 | Transcription factor MYC2 |
5gnj_G | 3e-13 | 160 | 223 | 12 | 75 | Transcription factor MYC2 |
5gnj_I | 3e-13 | 160 | 223 | 12 | 75 | Transcription factor MYC2 |
5gnj_M | 3e-13 | 160 | 223 | 12 | 75 | Transcription factor MYC2 |
5gnj_N | 3e-13 | 160 | 223 | 12 | 75 | Transcription factor MYC2 |
Search in ModeBase |
Functional Description ? help
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Source |
Description |
UniProt | Transcription factor. Essential protein involved in iron uptake responses. Regulates FRO2 at the level of mRNA accumulation and IRT1 at the level of protein accumulation. Confers enhanced iron mobilization responses at low iron supply. {ECO:0000269|PubMed:15539473, ECO:0000269|PubMed:15556641, ECO:0000269|PubMed:16117851}. |
Regulation -- Description ? help
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Source |
Description |
UniProt | INDUCTION: In roots by iron deficiency. Repressed by cytokinins. Induced by cold, UV, ethylene (ACC), jasmonic acid (JA), flagellin, and salicylic acid (SA) treatments. {ECO:0000269|PubMed:12679534, ECO:0000269|PubMed:15531708, ECO:0000269|PubMed:15539473, ECO:0000269|PubMed:15556641, ECO:0000269|PubMed:18397377}. |
Publications
? help Back to Top |
- Schmid NB, et al.
Feruloyl-CoA 6'-Hydroxylase1-dependent coumarins mediate iron acquisition from alkaline substrates in Arabidopsis. Plant Physiol., 2014. 164(1): p. 160-72 [PMID:24246380] - Doustaly F, et al.
Uranium perturbs signaling and iron uptake response in Arabidopsis thaliana roots. Metallomics, 2014. 6(4): p. 809-21 [PMID:24549117] - Le CT, et al.
ZINC FINGER OF ARABIDOPSIS THALIANA12 (ZAT12) Interacts with FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR (FIT) Linking Iron Deficiency and Oxidative Stress Responses. Plant Physiol., 2016. 170(1): p. 540-57 [PMID:26556796] - Yang L, et al.
Carbon Monoxide Interacts with Auxin and Nitric Oxide to Cope with Iron Deficiency in Arabidopsis. Front Plant Sci, 2016. 7: p. 112 [PMID:27014280] - Zhou C, et al.
Paenibacillus polymyxa BFKC01 enhances plant iron absorption via improved root systems and activated iron acquisition mechanisms. Plant Physiol. Biochem., 2016. 105: p. 162-173 [PMID:27105423] - Mai HJ,Pateyron S,Bauer P
Iron homeostasis in Arabidopsis thaliana: transcriptomic analyses reveal novel FIT-regulated genes, iron deficiency marker genes and functional gene networks. BMC Plant Biol., 2016. 16(1): p. 211 [PMID:27716045] - Zhou C, et al.
Exogenous Melatonin Improves Plant Iron Deficiency Tolerance via Increased Accumulation of Polyamine-Mediated Nitric Oxide. Int J Mol Sci, 2017. [PMID:27792144] - Ezer D, et al.
The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] - Naranjo-Arcos MA, et al.
Dissection of iron signaling and iron accumulation by overexpression of subgroup Ib bHLH039 protein. Sci Rep, 2017. 7(1): p. 10911 [PMID:28883478] - Kailasam S,Wang Y,Lo JC,Chang HF,Yeh KC
S-Nitrosoglutathione works downstream of nitric oxide to mediate iron-deficiency signaling in Arabidopsis. Plant J., 2018. 94(1): p. 157-168 [PMID:29396986] - Cui Y, et al.
Four IVa bHLH Transcription Factors Are Novel Interactors of FIT and Mediate JA Inhibition of Iron Uptake in Arabidopsis. Mol Plant, 2018. 11(9): p. 1166-1183 [PMID:29960107]
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