PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G015470.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family bHLH
Protein Properties Length: 558aa    MW: 61233 Da    PI: 7.9985
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G015470.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH56.35.8e-18264313255
                           HHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
                   HLH   2 rrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                           r +h++ E+rRR++iN++f++Lrel+P+     ++K +Ka+ L +++eYI++Lq
  HL.SW.v1.0.G015470.1 264 RSKHSATEQRRRSKINDRFQRLRELIPNI----DQKRDKASFLLEVIEYIQYLQ 313
                           889*************************6....69******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:4.10.280.101.5E-23259335IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474595.1E-19262339IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088817.346262312IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.18E-15264317No hitNo description
PfamPF000101.8E-15264313IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.8E-13268318IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006351Biological Processtranscription, DNA-templated
GO:0009742Biological Processbrassinosteroid mediated signaling pathway
GO:1902448Biological Processpositive regulation of shade avoidance
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 558 aa     Download sequence    Send to blast
MELSQPRPYG TEGRKPTHDF LSLYSHSTAH QDPRPPSEGG YLKTHDFLQP LERVGKTCAK  60
EEASVEISTS EKPPPPAPPP VEHVLPGGIG TYSISHISYF NQIQSRVPKP EGMVYPAAQA  120
SSTDRNDENS NCSSFTGSGF TLWEEPAVKK GKTGKENMAV DKPGVLEPAV RVGQWASSER  180
PSQSSSSNHR GSFSSLSSSQ PSAQRNQSFM EMIKSAKGCS QEEELEEEDQ FVHKKEVSTA  240
TTQRGELRVK VDGKSSDQKA NTPRSKHSAT EQRRRSKIND RFQRLRELIP NIDQKRDKAS  300
FLLEVIEYIQ YLQEKVHKHE GSFQGWSNEP EKLMPWRNNH RLVEAFDHSQ GLNGVSGPPL  360
VFSAQFDEKH ASVIPKAPGN AQHPVESDIS TATITNKGMT IPMSLQPNFF TPVRNGGASS  420
HAPSRLPSDL ENTSSQPQSQ LCQTRSCTTV DGAIASDKLK EEELTIEGGT ISISTAYSQG  480
LLDTLTQALQ RSGVDLSQAS ISVQIELGKR TSIRTTASTS ITKDNEIPSS NQGIKHFRVA  540
SVKDSDQAQK KLKTSKN*
Functional Description ? help Back to Top
Source Description
UniProtPositive brassinosteroid-signaling protein. Transcription factor that bind specifically to the DNA sequence 5'-CANNTG-3'(E box). Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BZR2/BES1. Does not itself activate transcription but enhances BZR2/BES1-mediated target gene activation. {ECO:0000269|PubMed:15680330}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00498DAPTransfer from AT5G08130Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by cold treatment. {ECO:0000269|PubMed:12679534}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024024837.10.0transcription factor BIM1 isoform X2
SwissprotQ9LEZ31e-127BIM1_ARATH; Transcription factor BIM1
TrEMBLA0A2P5EBR70.0A0A2P5EBR7_TREOI; Basic helix-loop-helix transcription factor
STRINGXP_010101635.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF72523145
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G08130.41e-122bHLH family protein
Publications ? help Back to Top
  1. Liang T, et al.
    UVR8 Interacts with BES1 and BIM1 to Regulate Transcription and Photomorphogenesis in Arabidopsis.
    Dev. Cell, 2018. 44(4): p. 512-523.e5
    [PMID:29398622]