PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus

Family

Dof

Protein Properties

Length: 304aa MW: 33171.9 Da PI: 7.4979

Description

Dof family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
HL.SW.v1.0.G014720.1	genome	HOPBASE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-Dof	128.2	2.3e-40	26	86	2	62
zf-Dof 2 kekalkcprCdstntkfCyynnyslsqPryfCkaCrryWtkGGalrnvPvGggrrknkkss 62 +++alkcprCdst+tkfCyynnyslsqPryfCk+CrryWtkGG+lrn+PvGgg+rknkk+s HL.SW.v1.0.G014720.1 26 HDQALKCPRCDSTHTKFCYYNNYSLSQPRYFCKTCRRYWTKGGTLRNIPVGGGCRKNKKVS 86 6899******************************************************987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
ProDom	PD007478	2.0E-28	20	80	IPR003851	Zinc finger, Dof-type
Pfam	PF02701	9.4E-34	27	84	IPR003851	Zinc finger, Dof-type
PROSITE profile	PS50884	29.189	30	84	IPR003851	Zinc finger, Dof-type
PROSITE pattern	PS01361	0	32	68	IPR003851	Zinc finger, Dof-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010067	Biological Process	procambium histogenesis
GO:0010087	Biological Process	phloem or xylem histogenesis
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 304 aa Download sequence Send to blast
MDSSSPSNDM LACSRPLMER RLRPPHDQAL KCPRCDSTHT KFCYYNNYSL SQPRYFCKTC 60 RRYWTKGGTL RNIPVGGGCR KNKKVSSKKP NDNNSDVVLA NNNNNNMNPV GPTDLQLAFP 120 DQVQYCHLMG SSASHGSGPN SFFESPRPID FMESKFEALV GNSSGNYDFM GNNTSNGDMG 180 MAGIGLGNLG GTHNNNHHHH HHGGGMVLEP NFNGLCPPYG MSLDGTSTGT FMDTCQRIML 240 PYEGNHEDQN GIDVKPNPKL LSLEWQDQGC SNAGKDSFGY LNGLGSWSGV MNNYGPSTSN 300 PLV*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Promotes expression (PubMed:19915089). The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) activate gene expression that promotes radial growth of protophloem sieve elements (PubMed:30626969). Involved in the regulation of interfascicular cambium formation and vascular tissue development, particularly at a very early stage during inflorescence stem development; promotes both cambium activity and phloem specification, but prevents xylem specification (PubMed:19915089). {ECO:0000250\|UniProtKB:Q9M2U1, ECO:0000269\|PubMed:19915089, ECO:0000269\|PubMed:30626969}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00580	DAP	Transfer from AT5G62940	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021292203.1	1e-138	dof zinc finger protein DOF5.6
Swissprot	Q9FM03	8e-47	DOF56_ARATH; Dof zinc finger protein DOF5.6
TrEMBL	A0A2P5AF62	1e-166	A0A2P5AF62_PARAD; Zinc finger, Dof-type
STRING	EOY20732	1e-136	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF5092	34	56

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G62940.1	2e-48	Dof family protein

Publications ? help Back to Top
Miyashima S, et al. Mobile PEAR transcription factors integrate positional cues to prime cambial growth. Nature, 2019. 565(7740): p. 490-494 [PMID:30626969]