PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G014484.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family WRKY
Protein Properties Length: 274aa    MW: 30474.1 Da    PI: 9.753
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G014484.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY48.71.5e-159481959
                          SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                  WRKY 19 efprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59
                          +  rsYY+Ct+++Cpvkk vers+  ++++ei+Y+++Hnh 
  HL.SW.v1.0.G014484.1  9 DKNRSYYKCTHPTCPVKKIVERSH-YGQITEIIYKSNHNHV 48
                          568*********************.9**************6 PP
2WRKY99.22.6e-31142200159
                           ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                  WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                           ldDgy+WrKYG+K+vkg+ +prsYY+Cts gC vkk+ver++ + k++++tYeg+Hnhe
  HL.SW.v1.0.G014484.1 142 LDDGYRWRKYGKKVVKGNSNPRSYYKCTSVGCIVKKHVERASGNVKAIITTYEGKHNHE 200
                           59********************************************************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM007746.6E-7649IPR003657WRKY domain
PfamPF031061.0E-10747IPR003657WRKY domain
Gene3DG3DSA:2.20.25.801.2E-11750IPR003657WRKY domain
SuperFamilySSF1182901.57E-10950IPR003657WRKY domain
PROSITE profilePS5081110.591250IPR003657WRKY domain
Gene3DG3DSA:2.20.25.807.7E-33127202IPR003657WRKY domain
SuperFamilySSF1182903.27E-27136202IPR003657WRKY domain
PROSITE profilePS5081134.842137202IPR003657WRKY domain
SMARTSM007744.5E-34142201IPR003657WRKY domain
PfamPF031063.9E-23143200IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 274 aa     Download sequence    Send to blast
MDTTGENMDK NRSYYKCTHP TCPVKKIVER SHYGQITEII YKSNHNHVKP QSNRRAGLGS  60
SAFSLGTPNE LFDPLSSVHG KSIELRETTS EVSTTVSSHG DADDDEPEAK RRKKLNYSSA  120
LSSGTVREPK IVIQIETDVD ILDDGYRWRK YGKKVVKGNS NPRSYYKCTS VGCIVKKHVE  180
RASGNVKAII TTYEGKHNHE VPAARNSNNH INSTGPNAPI PPITPNNSQS SSLKLPRNTT  240
IPKPQTQIQG PPPLFDRKPE FCNSDYLRPS FPGN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A4e-32133203878Probable WRKY transcription factor 4
2lex_A4e-32133203878Probable WRKY transcription factor 4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator (PubMed:26025535). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:19199048, PubMed:26025535). Negative regulator of both gibberellic acid (GA) and abscisic acid (ABA) signaling in aleurone cells, probably by interfering with GAM1, via the specific repression of GA- and ABA-induced promoters (PubMed:15618416, PubMed:19199048, PubMed:26025535). {ECO:0000269|PubMed:15618416, ECO:0000269|PubMed:19199048, ECO:0000269|PubMed:26025535}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in aleurone cells, embryos, roots and leaves (PubMed:15618416, PubMed:19199048). Slightly down-regulated by gibberellic acid (GA) (PubMed:15618416). Accumulates in response to jasmonic acid (MeJA) (By similarity). {ECO:0000250|UniProtKB:Q6B6R4, ECO:0000269|PubMed:15618416, ECO:0000269|PubMed:19199048}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010111075.17e-99WRKY transcription factor SUSIBA2
SwissprotQ6IEQ71e-66WRK24_ORYSJ; WRKY transcription factor WRKY24
TrEMBLA0A2P5CUG52e-99A0A2P5CUG5_PARAD; WRKY domain containing protein
STRINGXP_010111075.13e-98(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF83493445
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G38470.12e-62WRKY DNA-binding protein 33
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Zhang ZL, et al.
    A negative regulator encoded by a rice WRKY gene represses both abscisic acid and gibberellins signaling in aleurone cells.
    Plant Mol. Biol., 2009. 70(1-2): p. 139-51
    [PMID:19199048]
  3. Basu S,Roychoudhury A
    Expression profiling of abiotic stress-inducible genes in response to multiple stresses in rice (Oryza sativa L.) varieties with contrasting level of stress tolerance.
    Biomed Res Int, 2014. 2014: p. 706890
    [PMID:25110688]
  4. Zhang L, et al.
    Three WRKY transcription factors additively repress abscisic acid and gibberellin signaling in aleurone cells.
    Plant Sci., 2015. 236: p. 214-22
    [PMID:26025535]