PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus

Family

NAC

Protein Properties

Length: 474aa MW: 53598.2 Da PI: 6.4684

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
HL.SW.v1.0.G014470.1	genome	HOPBASE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	163.4	8.1e-51	15	143	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvka...eekewyfFskrdkkyatgkrknratksgyWkat 86 +ppGfrFhPt+eel+++yL+kkv+ +k++l +vi+evd++k+ePwd+++k+k +++wyfFs++dkky+tg+r+nrat++g+Wkat HL.SW.v1.0.G014470.1 15 VPPGFRFHPTEEELLHYYLRKKVAFEKIDL-DVIREVDLNKLEPWDIQEKCKIgstPQNDWYFFSHKDKKYPTGTRTNRATAAGFWKAT 102 69**************************.9***********964444222455************************** PP NAM 87 gkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128 g+dk ++s + + +gl+ktLvfykgrap+g+k+dW+mheyrl HL.SW.v1.0.G014470.1 103 GRDKIIYS-GFKRIGLRKTLVFYKGRAPHGQKSDWIMHEYRL 143 ****.9999*************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	3.53E-56	10	184	IPR003441	NAC domain
PROSITE profile	PS51005	55.606	15	184	IPR003441	NAC domain
Pfam	PF02365	1.8E-26	16	143	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 474 aa Download sequence Send to blast
MSEDMNLSIN GQSQVPPGFR FHPTEEELLH YYLRKKVAFE KIDLDVIREV DLNKLEPWDI 60 QEKCKIGSTP QNDWYFFSHK DKKYPTGTRT NRATAAGFWK ATGRDKIIYS GFKRIGLRKT 120 LVFYKGRAPH GQKSDWIMHE YRLDESTHDS TVVSPPNPKA HVSNQMVADS VSEDGWVVCR 180 VFKKKNYQKS LDSPKGATSS SMSGDSNMNN NGNNHSHLHH HLQMPCPRND GVLDQILLYM 240 GRTCKLENDS LANISAERYL TSSNKNATVG GGDAVFHQNF MHLPRLQESP TTTTTTTTTN 300 NNNNNSSTLH SLPLNDSVSP YKPYSYDHHQ SMEYDMLMET EPSSSDHRRT EDPKPVMVSN 360 RVNDWVALDR LVASQLNGQD HEETSKQVLS CFGDIQNVMS FCTTDPQTVV DDEDDVEQMS 420 SYPYLRSGTD MTTSTRTTSN LHNQNYNEND LWSFARSSSS PSSSSDPLCH LSV*

Sequence ? help Back to Top

Protein Sequence Length: 474 aa Download sequence Send to blast

MSEDMNLSIN GQSQVPPGFR FHPTEEELLH YYLRKKVAFE KIDLDVIREV DLNKLEPWDI  60
QEKCKIGSTP QNDWYFFSHK DKKYPTGTRT NRATAAGFWK ATGRDKIIYS GFKRIGLRKT  120
LVFYKGRAPH GQKSDWIMHE YRLDESTHDS TVVSPPNPKA HVSNQMVADS VSEDGWVVCR  180
VFKKKNYQKS LDSPKGATSS SMSGDSNMNN NGNNHSHLHH HLQMPCPRND GVLDQILLYM  240
GRTCKLENDS LANISAERYL TSSNKNATVG GGDAVFHQNF MHLPRLQESP TTTTTTTTTN  300
NNNNNSSTLH SLPLNDSVSP YKPYSYDHHQ SMEYDMLMET EPSSSDHRRT EDPKPVMVSN  360
RVNDWVALDR LVASQLNGQD HEETSKQVLS CFGDIQNVMS FCTTDPQTVV DDEDDVEQMS  420
SYPYLRSGTD MTTSTRTTSN LHNQNYNEND LWSFARSSSS PSSSSDPLCH LSV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	2e-47	15	186	15	170	Stress-induced transcription factor NAC1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator of genes involved in biosynthesis of secondary walls. Together with NST2 and NST3, required for the secondary cell wall thickening of sclerenchymatous fibers, secondary xylem (tracheary elements), and of the anther endocethium, which is necessary for anther dehiscence. May also regulate the secondary cell wall lignification of other tissues. {ECO:0000269\|PubMed:16214898, ECO:0000269\|PubMed:17237351, ECO:0000269\|PubMed:17333250}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010100216.1	0.0	NAC domain-containing protein 43
Swissprot	Q84WP6	1e-112	NAC43_ARATH; NAC domain-containing protein 43
TrEMBL	A0A2P5ANS9	0.0	A0A2P5ANS9_TREOI; NAC domain containing protein
STRING	XP_010100216.1	0.0	(Morus notabilis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF3031	33	74

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G46770.1	1e-99	NAC family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Gondolf VM, et al. A gene stacking approach leads to engineered plants with highly increased galactan levels in Arabidopsis. BMC Plant Biol., 2014. 14: p. 344 [PMID:25492673] Jaradat MR,Ruegger M,Bowling A,Butler H,Cutler AJ A comprehensive transcriptome analysis of silique development and dehiscence in Arabidopsis and Brassica integrating genotypic, interspecies and developmental comparisons. GM Crops Food, 2014. 5(4): p. 302-20 [PMID:25523176] Yuan Y,Teng Q,Zhong R,Ye ZH TBL3 and TBL31, Two Arabidopsis DUF231 Domain Proteins, are Required for 3-O-Monoacetylation of Xylan. Plant Cell Physiol., 2016. 57(1): p. 35-45 [PMID:26556650] Yang C, et al. Transcription Factor MYB26 Is Key to Spatial Specificity in Anther Secondary Thickening Formation. Plant Physiol., 2017. 175(1): p. 333-350 [PMID:28724622] Pascual MB, et al. PpNAC1, a main regulator of phenylalanine biosynthesis and utilization in maritime pine. Plant Biotechnol. J., 2018. 16(5): p. 1094-1104 [PMID:29055073] Liu C,Yu H,Li L SUMO modification of LBD30 by SIZ1 regulates secondary cell wall formation in Arabidopsis thaliana. PLoS Genet., 2019. 15(1): p. e1007928 [PMID:30657769]