PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G011145.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family NAC
Protein Properties Length: 149aa    MW: 17172.5 Da    PI: 9.8613
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G011145.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM157.55.7e-49181441128
                   NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgk 88 
                           + pGfrF+Ptdeel+++yLkkk+eg++ ++ evi+ev+i k+ePwdLp k+v  +++ew+fFs+r +ky++g++++rat+ gyWkatgk
  HL.SW.v1.0.G011145.1  18 MFPGFRFSPTDEELISFYLKKKMEGSEKSI-EVITEVEIWKYEPWDLPaKSVIPSNSEWFFFSPRGRKYPNGSQSRRATELGYWKATGK 105
                           579************************999.99***************555556888******************************** PP

                   NAM  89 dkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128
                           +++v+s +++ +g+k+tLvf+ grap+ge+t+W+mhey +
  HL.SW.v1.0.G011145.1 106 ERNVKS-GSTFIGTKRTLVFHIGRAPRGERTEWIMHEYCM 144
                           ******.999****************************86 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019411.96E-5211148IPR003441NAC domain
PROSITE profilePS5100550.36618149IPR003441NAC domain
PfamPF023652.5E-2620143IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009845Biological Processseed germination
GO:0009938Biological Processnegative regulation of gibberellic acid mediated signaling pathway
GO:0033619Biological Processmembrane protein proteolysis
GO:0048573Biological Processphotoperiodism, flowering
GO:0071472Biological Processcellular response to salt stress
GO:0005634Cellular Componentnucleus
GO:0005886Cellular Componentplasma membrane
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 149 aa     Download sequence    Send to blast
MVGTSSREAQ LSIAASSMFP GFRFSPTDEE LISFYLKKKM EGSEKSIEVI TEVEIWKYEP  60
WDLPAKSVIP SNSEWFFFSP RGRKYPNGSQ SRRATELGYW KATGKERNVK SGSTFIGTKR  120
TLVFHIGRAP RGERTEWIMH EYCMLDKSQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ut4_A1e-441714916147NO APICAL MERISTEM PROTEIN
1ut4_B1e-441714916147NO APICAL MERISTEM PROTEIN
1ut7_A1e-441714916147NO APICAL MERISTEM PROTEIN
1ut7_B1e-441714916147NO APICAL MERISTEM PROTEIN
3swm_A1e-441714919150NAC domain-containing protein 19
3swm_B1e-441714919150NAC domain-containing protein 19
3swm_C1e-441714919150NAC domain-containing protein 19
3swm_D1e-441714919150NAC domain-containing protein 19
3swp_A1e-441714919150NAC domain-containing protein 19
3swp_B1e-441714919150NAC domain-containing protein 19
3swp_C1e-441714919150NAC domain-containing protein 19
3swp_D1e-441714919150NAC domain-containing protein 19
4dul_A1e-441714916147NAC domain-containing protein 19
4dul_B1e-441714916147NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP), probably via metalloprotease activity. Regulates gibberellic acid-mediated salt-responsive repression of seed germination and flowering via FT, thus delaying seed germination under high salinity conditions. {ECO:0000269|PubMed:17410378, ECO:0000269|PubMed:18363782, ECO:0000269|PubMed:19704528, ECO:0000269|PubMed:19704545}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00280DAPTransfer from AT2G27300Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By high salt stress (PubMed:19704545, PubMed:17410378, PubMed:18363782, PubMed:19704528). Repressed by gibberellic acid (GA), but induced by the GA biosynthetic inhibitor paclabutrazol (PAC) (PubMed:18363782). Accumulates transiently in seeds upon imbibition (PubMed:19704545, PubMed:17410378, PubMed:18363782, PubMed:19704528). Induced by drought stress (PubMed:17158162). {ECO:0000269|PubMed:17158162, ECO:0000269|PubMed:17410378, ECO:0000269|PubMed:18363782, ECO:0000269|PubMed:19704528, ECO:0000269|PubMed:19704545}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024025054.12e-92NAC domain-containing protein 60
SwissprotQ9XIN74e-76NAC40_ARATH; NAC domain-containing protein 40
TrEMBLA0A2P5DZX94e-99A0A2P5DZX9_PARAD; NAC domain containing protein
STRINGXP_010102025.15e-91(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF73153346
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G27300.12e-78NTM1-like 8
Publications ? help Back to Top
  1. Liang M, et al.
    Subcellular Distribution of NTL Transcription Factors in Arabidopsis thaliana.
    Traffic, 2015. 16(10): p. 1062-74
    [PMID:26201836]
  2. Tian H, et al.
    NTL8 Regulates Trichome Formation in Arabidopsis by Directly Activating R3 MYB Genes TRY and TCL1.
    Plant Physiol., 2017. 174(4): p. 2363-2375
    [PMID:28649093]