PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus

Family

bHLH

Protein Properties

Length: 326aa MW: 34507 Da PI: 5.9683

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
HL.SW.v1.0.G007232.1	genome	HOPBASE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	31.3	3.6e-10	174	218	5	54
HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 h+++Er RR+ri +++ L+el+P++ K + a++L + v+Y+k L HL.SW.v1.0.G007232.1 174 HSIAERLRRERIAERMKALQELVPSC-----NKTDRAAMLDEIVDYVKFL 218 99*********************8.....6**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	1.14E-15	167	228	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	3.14E-11	167	223	No hit	No description
PROSITE profile	PS50888	16.526	169	218	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.0E-15	171	229	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.2E-7	174	218	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	6.6E-12	175	224	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 326 aa Download sequence Send to blast
MAGNPPENLG DDFLEQILAG QQSYTGGGGD MGSMPMVLQL GSGAGNVSGG SGPGGGFRGV 60 GMGMGMPLGL NLEQGFLRHD RFRDEVEVNN TNNNTNNLSS PVNATSAINE RDSVHMASLF 120 PAFGHLQNQS VRAAPPPPPP QLHQPTAPQV APAPQPPTMR PRVRARRGQA TDPHSIAERL 180 RRERIAERMK ALQELVPSCN KTDRAAMLDE IVDYVKFLRL QVKVLSMSRL GGAGAVAQLV 240 ADVPLSSVEG GGIEGGDSQA AWEKWSTDGT EQQVAKLMEE DVGAAMQFLQ SKALCIMPIS 300 LASAIFRTHQ PDGPTMVKPE SNSPS*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	178	183	RLRRER

Functional Description ? help Back to Top
Source	Description
UniProt	Required for ovule fertilization. {ECO:0000269\|PubMed:15634699}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015875423.1	1e-155	transcription factor UNE12-like isoform X1
Refseq	XP_015875424.1	1e-155	transcription factor UNE12-like isoform X2
Swissprot	O22768	4e-82	UNE12_ARATH; Transcription factor UNE12
TrEMBL	A0A2P5DKN1	1e-150	A0A2P5DKN1_PARAD; Basic helix-loop-helix transcription factor
STRING	EMJ06685	1e-145	(Prunus persica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF11205	32	39

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G02590.3	7e-66	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444]