PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus

Family

WOX

Protein Properties

Length: 307aa MW: 34500.4 Da PI: 6.7412

Description

WOX family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
HL.SW.v1.0.G006909.1	genome	HOPBASE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	61.9	9.6e-20	43	103	3	57
--SS--HHHHHHHHHHHHH..SSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS Homeobox 3 kRttftkeqleeLeelFek..nrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57 +R+t+t++q+++L++l+++ r p+ae++++++++l +++ ++V++WFqN++a+e++ HL.SW.v1.0.G006909.1 43 SRWTPTTDQIKILKDLYYNngVRSPTAEQIQKISARLrqygKIEGKNVFYWFQNHKARERQ 103 8***************8678***********************************97 PP
2	Wus_type_Homeobox	113.5	1.1e-36	41	105	2	65
Wus_type_Homeobox 2 artRWtPtpeQikiLeelyk.sGlrtPnkeeiqritaeLeeyGkiedkNVfyWFQNrkaRerqkq 65 +++RWtPt++QikiL++ly+ +G+r+P++e+iq+i+a+L++yGkie+kNVfyWFQN+kaRerqk+ HL.SW.v1.0.G006909.1 41 SSSRWTPTTDQIKILKDLYYnNGVRSPTAEQIQKISARLRQYGKIEGKNVFYWFQNHKARERQKK 105 789*************9779***************************************96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	1.58E-11	33	107	IPR009057	Homeodomain-like
PROSITE profile	PS50071	10.511	38	104	IPR001356	Homeobox domain
SMART	SM00389	1.3E-5	40	108	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	1.4E-7	43	103	IPR009057	Homeodomain-like
Pfam	PF00046	4.2E-17	43	103	IPR001356	Homeobox domain
CDD	cd00086	1.08E-6	44	105	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010492	Biological Process	maintenance of shoot apical meristem identity
GO:0080166	Biological Process	stomium development
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 307 aa Download sequence Send to blast
MEVSQQTNDD GHGGGQQQQQ QQQVVQQQGS SSSGGFLCRQ SSSRWTPTTD QIKILKDLYY 60 NNGVRSPTAE QIQKISARLR QYGKIEGKNV FYWFQNHKAR ERQKKRFTTT TTTTTSTTNT 120 TTSTATVTDS TLHPMQRGVI NPTVWKPHHH QYQSFNNHNK FSPAPNNNNN QMGHFGYGGV 180 NFRECGSSGV NGHNFGWVGV DPYSSTYNTL FEKRSITFDE EEEEEDNNNI AVEYEEIHSP 240 EIETLPLFPM HAEDINGYSN NFKPNYSGGA AYYSGWFCPD DGGRGGSRAS LELRLNSYSR 300 GSPDSF*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that plays a central role during developmental processes such as early embryogenesis and flowering, probably by regulating expression of specific genes. Required to specify stem cell identity in meristems, such as shoot apical meristem (SAM). Acts in parallel with HAM. {ECO:0000269\|PubMed:12208843}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00265	DAP	Transfer from AT2G17950	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015889667.1	2e-87	protein WUSCHEL
Swissprot	Q8LL11	2e-71	WUS_PETHY; Protein WUSCHEL
TrEMBL	A0A1Q3D8E1	2e-85	A0A1Q3D8E1_CEPFO; Homeobox domain-containing protein
STRING	XP_008241906.1	2e-81	(Prunus mume)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8241	33	45

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G17950.1	4e-42	WOX family protein

Publications ? help Back to Top
Stuurman J,Jäggi F,Kuhlemeier C Shoot meristem maintenance is controlled by a GRAS-gene mediated signal from differentiating cells. Genes Dev., 2002. 16(17): p. 2213-8 [PMID:12208843]