PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus

Family

bHLH

Protein Properties

Length: 294aa MW: 32628.5 Da PI: 7.1013

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
HL.SW.v1.0.G004441.1	genome	HOPBASE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	24.5	5e-08	184	231	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h+ +Er RR +iN+++ L++++P + k + a +L + ++Y++sLq HL.SW.v1.0.G004441.1 184 SHSLAERVRRGKINERLRCLQDIVPGC----YKTMGMAVMLDEIINYVQSLQ 231 8***********************9....35599999*******9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	4.19E-16	178	247	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	5.16E-10	178	235	No hit	No description
Gene3D	G3DSA:4.10.280.10	1.4E-15	180	241	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	15.097	180	230	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	3.4E-5	184	231	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	4.6E-8	186	236	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006351	Biological Process	transcription, DNA-templated
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 294 aa Download sequence Send to blast
MAEFAAYLQS SKPSFSFLEV DPNINMEEIT QFGGMNPHTA ENSNLLMNFQ SFVPFSSDNF 60 FGNPAAEFPG IIAENFPGNN SNYTNHQLYA HPTSSTHHHH QPTGSGNTNE ISHECKKRKA 120 FMTNLDASEC SSGNSSPPVS QVVGVQKKNG SGKGKRVKSN IEKEEEKPRE VVHVRARRGQ 180 ATDSHSLAER VRRGKINERL RCLQDIVPGC YKTMGMAVML DEIINYVQSL QNQVEFLSMK 240 LTAASTFYDF NSETDAVEKL QRAKAANEAK EMERLIREGY GGLACFHSAS WPL*

Functional Description ? help Back to Top
Source	Description
UniProt	Positive regulator of brassinosteroid signaling. {ECO:0000269\|PubMed:12454087}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by brassinosteroid, auxin and ethylene, and repressed by abscisic acid. Insensitive to gibberellic acid. {ECO:0000269\|PubMed:12454087}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024020295.1	1e-120	transcription factor BEE 1 isoform X2
Swissprot	Q8GWK7	2e-69	BEE3_ARATH; Transcription factor BEE 3
TrEMBL	A0A2P5APC8	1e-138	A0A2P5APC8_PARAD; Basic helix-loop-helix transcription factor
STRING	EOY21045	1e-112	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF3360	34	67

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G73830.1	6e-69	BR enhanced expression 3

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281]