PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus

Family

HD-ZIP

Protein Properties

Length: 325aa MW: 36333.6 Da PI: 8.4947

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
HL.SW.v1.0.G004319.1	genome	HOPBASE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	35.3	1.9e-11	186	214	28	56
HHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 28 eereeLAkklgLterqVkvWFqNrRakek 56 +++ LAk+l+L rqV vWFqNrRa+ k HL.SW.v1.0.G004319.1 186 KQKLALAKQLNLRPRQVEVWFQNRRARTK 214 57789**********************98 PP
2	HD-ZIP_I/II	104.7	7.2e-34	146	249	1	91
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLep..............erKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalke 75 +kk+rl+keq+ +LEe+F+e+++L+p ++K +la++L+l+prqv+vWFqnrRARtk+kq+E+d+e+Lkr++++l+e HL.SW.v1.0.G004319.1 146 RKKLRLTKEQSLVLEETFKEHNTLNPdsleikpkdlwrvqKQKLALAKQLNLRPRQVEVWFQNRRARTKLKQTEVDCEYLKRCCENLTE 234 69********************984444444444444458999**************************************** PP HD-ZIP_I/II 76 enerLekeveeLreel 91 en+rL+kev+eLr +l HL.SW.v1.0.G004319.1 235 ENRRLQKEVQELR-TL 249 **********9.44 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF04618	6.6E-33	1	117	IPR006712	HD-ZIP protein, N-terminal
SuperFamily	SSF46689	1.88E-13	134	217	IPR009057	Homeodomain-like
PROSITE profile	PS50071	14.852	142	216	IPR001356	Homeobox domain
SMART	SM00389	1.4E-10	144	220	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	1.6E-14	146	219	IPR009057	Homeodomain-like
CDD	cd00086	9.90E-11	146	217	No hit	No description
Pfam	PF00046	7.1E-9	186	214	IPR001356	Homeobox domain
PROSITE pattern	PS00027	0	191	214	IPR017970	Homeobox, conserved site
Pfam	PF02183	6.9E-11	216	249	IPR003106	Leucine zipper, homeobox-associated
SMART	SM00340	2.6E-26	216	259	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 325 aa Download sequence Send to blast
MGENDDGLGL SLSLGCGATQ PSVKLNLMQK PSPPMQYHHH HHHHRQKTPW NEIFQLSNDR 60 NSDSRSFLRG LDVNRAPDSA TSATAATAAA ADYEDENGVS SPNSTVSSIS GKRSERELIG 120 EEIENERDSC SRGSDDEDGG GGDNSRKKLR LTKEQSLVLE ETFKEHNTLN PDSLEIKPKD 180 LWRVQKQKLA LAKQLNLRPR QVEVWFQNRR ARTKLKQTEV DCEYLKRCCE NLTEENRRLQ 240 KEVQELRTLK LSPQLYMHMS PPTTLTMCPS CERVAVTSSS SSTAASSAPN RPHAIPGVSR 300 PVPINRWAAL PIQHRPKDAQ VSRS*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	144	150	SRKKLRL
2	208	216	RRARTKLKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000250}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KP229720	8e-87	KP229720.1 UNVERIFIED: Boehmeria nivea Homeobox-leucine zipper protein-like (HDZIP21) mRNA, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_022756941.1	1e-141	homeobox-leucine zipper protein HAT3
Swissprot	P46602	1e-103	HAT3_ARATH; Homeobox-leucine zipper protein HAT3
TrEMBL	A0A2P5CIJ5	1e-165	A0A2P5CIJ5_PARAD; Octamer-binding transcription factor
STRING	XP_006464444.1	1e-136	(Citrus sinensis)
STRING	XP_006445396.1	1e-136	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1239	34	105

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G60390.1	2e-67	homeobox-leucine zipper protein 3

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zou LJ, et al. Role of Transcription Factor HAT1 in Modulating Arabidopsis thaliana Response to Cucumber mosaic virus. Plant Cell Physiol., 2016. 57(9): p. 1879-89 [PMID:27328697] Caggiano MP, et al. Cell type boundaries organize plant development. Elife, 2018. [PMID:28895530]