PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus

Family

WRKY

Protein Properties

Length: 335aa MW: 36411.9 Da PI: 6.8605

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
HL.SW.v1.0.G004228.1	genome	HOPBASE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	104.2	7e-33	165	222	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 +Dgy+WrKYGqK vk+s+fprsYYrCt ++C+vkk+vers+edp++v++tYeg+H h+ HL.SW.v1.0.G004228.1 165 EDGYRWRKYGQKAVKNSPFPRSYYRCTNSKCTVKKRVERSSEDPTIVITTYEGQHCHH 222 8******************************************************997 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	5.4E-34	149	223	IPR003657	WRKY domain
SuperFamily	SSF118290	3.92E-28	156	222	IPR003657	WRKY domain
PROSITE profile	PS50811	29.712	159	224	IPR003657	WRKY domain
SMART	SM00774	3.2E-38	164	223	IPR003657	WRKY domain
Pfam	PF03106	1.2E-25	165	222	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009414	Biological Process	response to water deprivation
GO:0009651	Biological Process	response to salt stress
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 335 aa Download sequence Send to blast
MDDVDKFKSD LGGGGGAGTE FGSQSSWTHF GGPDSDDGGY FFSPADRETS ILSEFGWNFH 60 TEDDDQLART TESERAGKLE RSMTADVAES STGTEIAARI GSTTTSNNPS VSSSSSEDPT 120 EKSTGSGGKP PPDQIPNNKV KKKGQKRMRQ PRFAFMTKSE VDHLEDGYRW RKYGQKAVKN 180 SPFPRSYYRC TNSKCTVKKR VERSSEDPTI VITTYEGQHC HHTVGFPRGG IVAHPDLAAA 240 YPGSHHLTQP VSKFYYTAIN PSLNTESSSD NNAYNNNNNP NLVTNNMIHQ SNQVITSEAG 300 NSALIIMKEK SSTPLQVSAE GLLGDIVPPG MRSR*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	2e-25	154	221	7	74	Probable WRKY transcription factor 4
2lex_A	2e-25	154	221	7	74	Probable WRKY transcription factor 4
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00067	PBM	Transfer from AT1G69310	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010109362.1	1e-118	probable WRKY transcription factor 57
Refseq	XP_024029869.1	1e-118	probable WRKY transcription factor 57
Refseq	XP_024029871.1	1e-118	probable WRKY transcription factor 57
Refseq	XP_024029872.1	1e-118	probable WRKY transcription factor 57
Refseq	XP_024029873.1	1e-118	probable WRKY transcription factor 57
Swissprot	Q9C983	1e-72	WRK57_ARATH; Probable WRKY transcription factor 57
TrEMBL	A0A2P5E284	1e-140	A0A2P5E284_PARAD; WRKY domain containing protein
STRING	XP_010109362.1	1e-118	(Morus notabilis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF10814	31	40

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G69310.2	1e-62	WRKY DNA-binding protein 57

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Jiang Y,Qiu Y,Hu Y,Yu D Heterologous Expression of AtWRKY57 Confers Drought Tolerance in Oryza sativa. Front Plant Sci, 2016. 7: p. 145 [PMID:26904091] Jiang Y,Yu D The WRKY57 Transcription Factor Affects the Expression of Jasmonate ZIM-Domain Genes Transcriptionally to Compromise Botrytis cinerea Resistance. Plant Physiol., 2016. 171(4): p. 2771-82 [PMID:27268959] Huang KC,Lin WC,Cheng WH Salt hypersensitive mutant 9, a nucleolar APUM23 protein, is essential for salt sensitivity in association with the ABA signaling pathway in Arabidopsis. BMC Plant Biol., 2018. 18(1): p. 40 [PMID:29490615]