PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus

Family

WRKY

Protein Properties

Length: 385aa MW: 42344.4 Da PI: 6.2629

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
HL.SW.v1.0.G001346.1	genome	HOPBASE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	107.2	8.3e-34	201	258	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 +Dgy+WrKYGqK vk+s+fprsYYrCtsa+C+vkk+vers +dp+vv++tYeg+H+h+ HL.SW.v1.0.G001346.1 201 EDGYRWRKYGQKAVKNSPFPRSYYRCTSASCNVKKRVERSYTDPSVVVTTYEGQHTHP 258 8********************************************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PIRSF	PIRSF038130	7.0E-99	16	384	IPR017396	PWRKY transcription factor, group IIc
Gene3D	G3DSA:2.20.25.80	1.0E-34	185	260	IPR003657	WRKY domain
SuperFamily	SSF118290	2.48E-29	192	260	IPR003657	WRKY domain
PROSITE profile	PS50811	32.202	195	260	IPR003657	WRKY domain
SMART	SM00774	8.8E-40	200	259	IPR003657	WRKY domain
Pfam	PF03106	1.5E-26	201	258	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009624	Biological Process	response to nematode
GO:0009733	Biological Process	response to auxin
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 385 aa Download sequence Send to blast
MEMKREMSNT TTTTTKDNNM MGSSSLSDII SNGSFPMFSS TNTFEPSSDF GAENKGSTLG 60 FMELLGVNDY FTIPPSSFFD FPALLASNTT TSTITTTAVP PLTIPKKEVS SDALNSNNNN 120 QPATPNTSSI SSASSDALNE EQTKPADPEE EEEEDEGEED EEEEQPAKTT NKQLKAKKTN 180 QKKQREPRFA FMTKSEVDHL EDGYRWRKYG QKAVKNSPFP RSYYRCTSAS CNVKKRVERS 240 YTDPSVVVTT YEGQHTHPSP LISRPTHTAA ADHPAAAFAN IPFHRSSGHH HQLPHQYQFM 300 TDHHHLLSSP SPSPSPASLP SNHNSFANYS NIISHINSNN NGSTTNAAAA FLHERRFCNP 360 SPGPALIPDH GLLQDIVTSN MRTN*

Sequence ? help Back to Top

Protein Sequence Length: 385 aa Download sequence Send to blast

MEMKREMSNT TTTTTKDNNM MGSSSLSDII SNGSFPMFSS TNTFEPSSDF GAENKGSTLG  60
FMELLGVNDY FTIPPSSFFD FPALLASNTT TSTITTTAVP PLTIPKKEVS SDALNSNNNN  120
QPATPNTSSI SSASSDALNE EQTKPADPEE EEEEDEGEED EEEEQPAKTT NKQLKAKKTN  180
QKKQREPRFA FMTKSEVDHL EDGYRWRKYG QKAVKNSPFP RSYYRCTSAS CNVKKRVERS  240
YTDPSVVVTT YEGQHTHPSP LISRPTHTAA ADHPAAAFAN IPFHRSSGHH HQLPHQYQFM  300
TDHHHLLSSP SPSPSPASLP SNHNSFANYS NIISHINSNN NGSTTNAAAA FLHERRFCNP  360
SPGPALIPDH GLLQDIVTSN MRTN*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	8e-26	193	260	10	77	Probable WRKY transcription factor 4
2lex_A	8e-26	193	260	10	77	Probable WRKY transcription factor 4
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00069	PBM	Transfer from AT2G47260	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021654615.1	1e-90	probable WRKY transcription factor 23 isoform X1
Swissprot	O22900	6e-65	WRK23_ARATH; WRKY transcription factor 23
TrEMBL	A0A2P5B869	1e-103	A0A2P5B869_TREOI; WRKY domain containing protein
STRING	XP_009367202.1	4e-87	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1002	34	114

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G47260.1	4e-46	WRKY DNA-binding protein 23

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Guo D,Qin G EXB1/WRKY71 transcription factor regulates both shoot branching and responses to abiotic stresses. Plant Signal Behav, 2016. 11(3): p. e1150404 [PMID:26914912] Prát T, et al. WRKY23 is a component of the transcriptional network mediating auxin feedback on PIN polarity. PLoS Genet., 2018. 14(1): p. e1007177 [PMID:29377885]