PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gorai.013G036400.1

Common Name

B456_013G036400, LOC105783443

Organism

Gossypium raimondii

Taxonomic ID

29730

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

bHLH

Protein Properties

Length: 437aa MW: 48108.3 Da PI: 5.5581

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gorai.013G036400.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	30.7	5.8e-10	236	283	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h+ +Er RR++i +++ L++l+P + +k Ka +L + ++Y++sLq Gorai.013G036400.1 236 SHSLAERVRREKISERMKYLQDLVPGC----NKITGKAGMLDEIINYVQSLQ 283 8************************....999***************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00083	2.26E-10	230	287	No hit	No description
SuperFamily	SSF47459	6.41E-17	230	301	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	3.6E-17	232	299	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	15.618	232	282	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	2.4E-7	236	283	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	2.3E-9	238	288	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 437 aa Download sequence Send to blast
MNTALPEMLQ CSDLTVLERQ RDRLKWQEEQ FQQQQQQSYF SELSCGAFSS QTNHVQGFQG 60 GFMGGASGDS VLSDMVMARQ VKPDPGLESP WPELGKVDMA AMGFGPCGYG NGPSFDMNHA 120 ISRTSSCPPA VAATKAVEVK VNSEKMASAV DKESFKKRKA EKLQNTKVVA ENESKRIKSC 180 EDEGEESKIT GPNTNKSSNN KKEASGDASK ENSKVSEVQK PDFIHVRARR GQATDSHSLA 240 ERVRREKISE RMKYLQDLVP GCNKITGKAG MLDEIINYVQ SLQRQVEFLS MKLATVNPRL 300 DFNIDNLYAK EVFSSCTPNF PTLGMAPEMA NPPYLQFNPI QQVVPCCGVE MGINSPDMTL 360 RRTISAPVSI PDASFLDSSC LTMHQCSAMQ QIQPTATWDV ELQNLYNVAF DQGRSTPPFP 420 SQPFAGSIEA SDLKEI*

Sequence ? help Back to Top

Protein Sequence Length: 437 aa Download sequence Send to blast

MNTALPEMLQ CSDLTVLERQ RDRLKWQEEQ FQQQQQQSYF SELSCGAFSS QTNHVQGFQG  60
GFMGGASGDS VLSDMVMARQ VKPDPGLESP WPELGKVDMA AMGFGPCGYG NGPSFDMNHA  120
ISRTSSCPPA VAATKAVEVK VNSEKMASAV DKESFKKRKA EKLQNTKVVA ENESKRIKSC  180
EDEGEESKIT GPNTNKSSNN KKEASGDASK ENSKVSEVQK PDFIHVRARR GQATDSHSLA  240
ERVRREKISE RMKYLQDLVP GCNKITGKAG MLDEIINYVQ SLQRQVEFLS MKLATVNPRL  300
DFNIDNLYAK EVFSSCTPNF PTLGMAPEMA NPPYLQFNPI QQVVPCCGVE MGINSPDMTL  360
RRTISAPVSI PDASFLDSSC LTMHQCSAMQ QIQPTATWDV ELQNLYNVAF DQGRSTPPFP  420
SQPFAGSIEA SDLKEI*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed constitutively in roots, leaves, and stems. {ECO:0000269\|PubMed:12679534}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds DNA to G box 5'-CACGTG-3' and, to a lower extent, to E-box 5'-CANNTG-3' in vitro. Binds to chromatin DNA of the FT gene and promotes its expression, and thus triggers flowering in response to blue light. {ECO:0000269\|PubMed:18988809, ECO:0000269\|PubMed:24130508}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Accumulates strongly in response to blue light due to reduced preventing 26S proteasome-mediated degradation in an ADO1/ZTL and ADO2/LKP2 dependent manner, but levels decrease in the absence of blue light via 26S proteasome degradation (at protein level). {ECO:0000269\|PubMed:24101505}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	EU532258	0.0	EU532258.1 Gossypium barbadense clone I8-1 ISSR marker genomic sequence.
GenBank	EU532309	0.0	EU532309.1 Gossypium barbadense clone I11-11 ISSR marker genomic sequence.
GenBank	EU532316	0.0	EU532316.1 Gossypium barbadense clone I11-19 ISSR marker genomic sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012464358.1	0.0	PREDICTED: transcription factor HBI1-like
Swissprot	Q8GY61	3e-60	BH063_ARATH; Transcription factor bHLH63
TrEMBL	A0A0D2S7U4	0.0	A0A0D2S7U4_GOSRA; Uncharacterized protein
STRING	Gorai.013G036400.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5947	25	43

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G34530.1	2e-62	cryptochrome-interacting basic-helix-loop-helix 1

Link Out ? help Back to Top
Phytozome	Gorai.013G036400.1
Entrez Gene	105783443

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Paterson AH, et al. Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature, 2012. 492(7429): p. 423-7 [PMID:23257886] Yang D,Zhao W,Meng Y,Li H,Liu B A CIB1-LIKE transcription factor GmCIL10 from soybean positively regulates plant flowering. Sci China Life Sci, 2015. 58(3): p. 261-9 [PMID:25651969] Katsura Y, et al. An optogenetic system for interrogating the temporal dynamics of Akt. Sci Rep, 2015. 5: p. 14589 [PMID:26423353] Taslimi A, et al. Optimized second-generation CRY2-CIB dimerizers and photoactivatable Cre recombinase. Nat. Chem. Biol., 2016. 12(6): p. 425-30 [PMID:27065233] Liu Q, et al. The Blue Light-Dependent Polyubiquitination and Degradation of Arabidopsis Cryptochrome2 Requires Multiple E3 Ubiquitin Ligases. Plant Cell Physiol., 2016. 57(10): p. 2175-2186 [PMID:27516416] Pathak GP, et al. Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2. Nucleic Acids Res., 2017. 45(20): p. e167 [PMID:28431041] Duan L, et al. Understanding CRY2 interactions for optical control of intracellular signaling. Nat Commun, 2017. 8(1): p. 547 [PMID:28916751] Quejada JR, et al. Optimized light-inducible transcription in mammalian cells using Flavin Kelch-repeat F-box1/GIGANTEA and CRY2/CIB1. Nucleic Acids Res., 2017. 45(20): p. e172 [PMID:29040770] Liu Y, et al. CIB1 and CO interact to mediate CRY2-dependent regulation of flowering. EMBO Rep., 2019. [PMID:30126927]