PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

CAMTA

Protein Properties

Length: 1088aa MW: 123051 Da PI: 6.5749

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gorai.008G089900.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	179	6e-56	20	136	2	118
CG-1 2 lkekkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenp 92 l+ ++rwl++ ei++iL n++k+++++e+++ p+sgsl+L++rk++ryfrkDG++w+kkkdgktv+E+he+LK g+++vl+cyYah+een+ Gorai.008G089900.1 20 LEAQHRWLRPAEICEILRNYKKFHISSEPAHMPPSGSLFLFDRKVLRYFRKDGHNWRKKKDGKTVKEAHERLKAGSIDVLHCYYAHGEENE 110 5679************************************************************************************* PP CG-1 93 tfqrrcywlLeeelekivlvhylevk 118 +fqrr+yw+Lee+l++ivlvhy++vk Gorai.008G089900.1 111 NFQRRSYWMLEEDLSHIVLVHYRDVK 136 *********************985 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	82.853	15	141	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	8.2E-79	18	136	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	1.5E-49	21	135	IPR005559	CG-1 DNA-binding domain
Gene3D	G3DSA:2.60.40.10	5.4E-6	503	590	IPR013783	Immunoglobulin-like fold
SuperFamily	SSF81296	8.87E-19	504	590	IPR014756	Immunoglobulin E-set
Pfam	PF01833	1.6E-6	504	589	IPR002909	IPT domain
Gene3D	G3DSA:1.25.40.20	1.1E-14	687	800	IPR020683	Ankyrin repeat-containing domain
PROSITE profile	PS50297	16.52	688	799	IPR020683	Ankyrin repeat-containing domain
CDD	cd00204	7.84E-12	688	797	No hit	No description
SuperFamily	SSF48403	1.32E-14	689	800	IPR020683	Ankyrin repeat-containing domain
SMART	SM00248	0.03	738	767	IPR002110	Ankyrin repeat
PROSITE profile	PS50088	9.217	738	770	IPR002110	Ankyrin repeat
SMART	SM00248	1000	777	806	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	8.5E-9	908	963	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	0.016	912	934	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.0021	914	933	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	8.297	914	942	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	0.0039	935	957	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.578	936	960	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	2.2E-4	938	957	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009409	Biological Process	response to cold
GO:0010150	Biological Process	leaf senescence
GO:0042742	Biological Process	defense response to bacterium
GO:0050832	Biological Process	defense response to fungus
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005516	Molecular Function	calmodulin binding

Sequence ? help Back to Top
Protein Sequence Length: 1088 aa Download sequence Send to blast
MAESRRYVLT NQLDIDQILL EAQHRWLRPA EICEILRNYK KFHISSEPAH MPPSGSLFLF 60 DRKVLRYFRK DGHNWRKKKD GKTVKEAHER LKAGSIDVLH CYYAHGEENE NFQRRSYWML 120 EEDLSHIVLV HYRDVKGNRT NFNRLKETEG GIPYSQEAVG IVPNSEVESS LSSNFLPNNS 180 QIPSQTMDTA SMNSVHVQAS EYEDAESVSN HQASSQFHSF LDSHQPVAGR ADTRFYDPYV 240 HVSHSNNCYG KPSITAFQLT QTDKDREYNV AGITYEPQKN LDFTSWEDVL ENCDRGVESA 300 QYQPPFTLKQ NDTVGLLFDN SFLKKQAFED QSHAQEEWQG YEGDSSHIVK WSLDQKLHPD 360 LRYDLTSKFD EEVNHNLHPE KQHDHYLLNN QLTDPSKGDH EYVPKPDSEN YLTLEGKSVY 420 SSAMRPHLFD GSLAEGLKKL DSFNRWMSKE LGDVDESHTH SSSGAYWDEV EGQNGIDVSS 480 IPSQEQLDTF MLGPSLSHDQ LFSIIDFSPN WAYVGSEIKV LITGRFLKSQ GHAENCKWSC 540 MFGEVEVPAE VIADGVLRCH TPKHEAGRVP FYVTCSNRLA CSEVREFEYR VSHILDIDTV 600 DNPSSNAIKI LDMRFGRLLC LGSSSPASNT NSIADISQLS SKINSLLKED VEEWDQMLAH 660 NLEEDFFLEK LKEQLLKKLL KEKLRVWLLQ KIVEGGKGPS ILDKGGQGVI HFASALGYDW 720 ALEPTIVAGV SVNFRDVNGW NALHWAASSG RERTVASLIS LGAAPGALTD PTPEYPLGRT 780 PADLASANGH KGISGYLAEC DLSSHLLSLN LDKQGSASTT DSRPDVIQKI LELKTAPLNY 840 GDASDGPSLK DSLAAVRNAT QAAARIHQVF RVQSFQNRQL KEYGNDKYGM SDERALSLLA 900 VKSNKPGQHD ERVHAAAIRI QNKFRGWKGR KEFLIIRQRI VKIQAHVRGH QVRKNYRKIV 960 WSVGIVEKVI LRWRRKGSGL RGFKPETLTK GPSVSVPSKE DDYDFLKKGR KQTEERLQKA 1020 LARVKSMALN PAGRDQYSRI KNVVTEIQEK VLYDKVLNFA GETTDLDKDL IDLEKLLDED 1080 TFMQTAP*

Sequence ? help Back to Top

Protein Sequence Length: 1088 aa Download sequence Send to blast

MAESRRYVLT NQLDIDQILL EAQHRWLRPA EICEILRNYK KFHISSEPAH MPPSGSLFLF  60
DRKVLRYFRK DGHNWRKKKD GKTVKEAHER LKAGSIDVLH CYYAHGEENE NFQRRSYWML  120
EEDLSHIVLV HYRDVKGNRT NFNRLKETEG GIPYSQEAVG IVPNSEVESS LSSNFLPNNS  180
QIPSQTMDTA SMNSVHVQAS EYEDAESVSN HQASSQFHSF LDSHQPVAGR ADTRFYDPYV  240
HVSHSNNCYG KPSITAFQLT QTDKDREYNV AGITYEPQKN LDFTSWEDVL ENCDRGVESA  300
QYQPPFTLKQ NDTVGLLFDN SFLKKQAFED QSHAQEEWQG YEGDSSHIVK WSLDQKLHPD  360
LRYDLTSKFD EEVNHNLHPE KQHDHYLLNN QLTDPSKGDH EYVPKPDSEN YLTLEGKSVY  420
SSAMRPHLFD GSLAEGLKKL DSFNRWMSKE LGDVDESHTH SSSGAYWDEV EGQNGIDVSS  480
IPSQEQLDTF MLGPSLSHDQ LFSIIDFSPN WAYVGSEIKV LITGRFLKSQ GHAENCKWSC  540
MFGEVEVPAE VIADGVLRCH TPKHEAGRVP FYVTCSNRLA CSEVREFEYR VSHILDIDTV  600
DNPSSNAIKI LDMRFGRLLC LGSSSPASNT NSIADISQLS SKINSLLKED VEEWDQMLAH  660
NLEEDFFLEK LKEQLLKKLL KEKLRVWLLQ KIVEGGKGPS ILDKGGQGVI HFASALGYDW  720
ALEPTIVAGV SVNFRDVNGW NALHWAASSG RERTVASLIS LGAAPGALTD PTPEYPLGRT  780
PADLASANGH KGISGYLAEC DLSSHLLSLN LDKQGSASTT DSRPDVIQKI LELKTAPLNY  840
GDASDGPSLK DSLAAVRNAT QAAARIHQVF RVQSFQNRQL KEYGNDKYGM SDERALSLLA  900
VKSNKPGQHD ERVHAAAIRI QNKFRGWKGR KEFLIIRQRI VKIQAHVRGH QVRKNYRKIV  960
WSVGIVEKVI LRWRRKGSGL RGFKPETLTK GPSVSVPSKE DDYDFLKKGR KQTEERLQKA  1020
LARVKSMALN PAGRDQYSRI KNVVTEIQEK VLYDKVLNFA GETTDLDKDL IDLEKLLDED  1080
TFMQTAP*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, stems, leaves, carpels, and siliques, but not in stigmas or other parts of the flower. {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:14581622}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00042	PBM	Transfer from AT2G22300	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012437207.1	0.0	PREDICTED: calmodulin-binding transcription activator 3 isoform X1
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A0D2RC84	0.0	A0A0D2RC84_GOSRA; Uncharacterized protein
STRING	Gorai.008G089900.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM8601	25	35

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22300.2	0.0	signal responsive 1

Link Out ? help Back to Top
Phytozome	Gorai.008G089900.1
Entrez Gene	105763524

Publications ? help Back to Top
Paterson AH, et al. Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature, 2012. 492(7429): p. 423-7 [PMID:23257886] Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]