PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

bHLH

Protein Properties

Length: 324aa MW: 33897.4 Da PI: 6.0913

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gorai.007G277200.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	31.3	3.6e-10	173	217	5	54
HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 h+++Er RR+ri +++ L+el+P++ K + a++L + v+Y+k L Gorai.007G277200.1 173 HSIAERLRRERIAERMKALQELVPSC-----NKTDRAAMLDEIVDYVKFL 217 99*********************8.....6**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	9.29E-16	166	228	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	16.526	168	217	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	6.7E-16	170	230	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.77E-11	172	222	No hit	No description
Pfam	PF00010	1.2E-7	173	217	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	6.6E-12	174	223	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 324 aa Download sequence Send to blast
MAGNQQQEAG LGDDFFEQIL AVPPGYGGGA TLPMGLQLGS SGGATGASGG DSGGGGFRGI 60 GMMPLGLNLE HGFLRHEDGV VVDNNNNNAS CSAASAVSGI SERDSMHMVS LFPPFGQMQT 120 QQIRASPPPP QPPPQLHQPF HSQPTSGPVA AAPHPPAVRP RVRARRGQAT DPHSIAERLR 180 RERIAERMKA LQELVPSCNK TDRAAMLDEI VDYVKFLRLQ VKVLSMSRLG AAGAVAQLVA 240 DVPLLSVEGD GAGGGTQPAW EKWSNDGTEQ QVAKLMEEDI GAAMQFLQSK ALCIVPISLA 300 SAIFPAHQPD APTIVKPESN TPS*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	177	182	RLRRER

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems, and flowers. {ECO:0000269\|PubMed:12679534}.

Functional Description ? help Back to Top
Source	Description
UniProt	Required for ovule fertilization. {ECO:0000269\|PubMed:15634699}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HQ525196	1e-100	HQ525196.1 Gossypium herbaceum clone NBRI_D2_1401 simple sequence repeat marker, mRNA sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012492792.1	0.0	PREDICTED: transcription factor UNE12-like
Swissprot	O22768	2e-84	UNE12_ARATH; Transcription factor UNE12
TrEMBL	A0A0D2SS58	0.0	A0A0D2SS58_GOSRA; Uncharacterized protein
STRING	Gorai.007G277200.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1611	28	88

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G02590.3	2e-59	bHLH family protein

Link Out ? help Back to Top
Phytozome	Gorai.007G277200.1
Entrez Gene	105804644

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Paterson AH, et al. Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature, 2012. 492(7429): p. 423-7 [PMID:23257886] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444]