PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

MYB

Protein Properties

Length: 552aa MW: 61209.9 Da PI: 8.2901

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gorai.006G172800.2	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	53.7	4.6e-17	59	105	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g WT+eEde l +av+ + g++Wk+Ia+ ++ R++ qc +rwqk+l Gorai.006G172800.2 59 KGGWTPEEDETLRNAVATFKGKSWKKIAEFFP-DRSEVQCLHRWQKVL 105 688***************************.**********986 PP
2	Myb_DNA-binding	61.7	1.5e-19	111	157	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+WT+eEd+++v++v ++G+ W+ Ia+ ++ gR +kqc++rw+++l Gorai.006G172800.2 111 KGPWTQEEDDKIVELVSKYGPTKWSVIAKSLP-GRIGKQCRERWHNHL 157 79****************************.***********97 PP
3	Myb_DNA-binding	53.5	5.5e-17	163	206	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 +++WT eE++ l +a++ +G++ W+ Ia+ ++ gRt++ +k++w++ Gorai.006G172800.2 163 KDAWTLEEELALMNAHRIYGNK-WAEIAKVLP-GRTDNAIKNHWNS 206 679*****************.*****.*********96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	15.725	54	105	IPR017930	Myb domain
SMART	SM00717	7.4E-15	58	107	IPR001005	SANT/Myb domain
Pfam	PF00249	8.3E-16	59	105	IPR001005	SANT/Myb domain
SuperFamily	SSF46689	1.58E-15	60	115	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	1.1E-22	61	113	IPR009057	Homeodomain-like
CDD	cd00167	7.37E-13	62	105	No hit	No description
PROSITE profile	PS51294	32.538	106	161	IPR017930	Myb domain
SuperFamily	SSF46689	4.87E-32	108	204	IPR009057	Homeodomain-like
SMART	SM00717	3.2E-18	110	159	IPR001005	SANT/Myb domain
Pfam	PF00249	1.2E-18	111	157	IPR001005	SANT/Myb domain
CDD	cd00167	1.36E-15	113	157	No hit	No description
Gene3D	G3DSA:1.10.10.60	1.7E-27	114	160	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	4.0E-23	161	212	IPR009057	Homeodomain-like
PROSITE profile	PS51294	22.308	162	212	IPR017930	Myb domain
SMART	SM00717	5.9E-16	162	210	IPR001005	SANT/Myb domain
Pfam	PF00249	5.1E-15	163	206	IPR001005	SANT/Myb domain
CDD	cd00167	4.90E-12	165	205	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 552 aa Download sequence Send to blast
MTELKIEERC LENKQLTTAS SSSVSEGGGS AIVKSPATSS PAPTSPNHRR TTGPIRRAKG 60 GWTPEEDETL RNAVATFKGK SWKKIAEFFP DRSEVQCLHR WQKVLNPDLV KGPWTQEEDD 120 KIVELVSKYG PTKWSVIAKS LPGRIGKQCR ERWHNHLNPD IKKDAWTLEE ELALMNAHRI 180 YGNKWAEIAK VLPGRTDNAI KNHWNSSMKK KLDFYLATGK LPPVVKIVLK NEIKDIETPA 240 ATENLLVCSK KESDSTAQTS SGTFDICKPE EDGKDQLESS TPVQDMAATS SIIPSESVET 300 ESAEFKPQSF DANPCSCNSV SMVKFESRRT SSAIVEDKVV ETQLRSDTPT YGPLCYEPPR 360 LQGGTSLDSD NLNKKGMQHE WTITPITSPL SFFTPPCVKG SGFGTQSPES ILRIAAKTFP 420 STPSIFRKRK TSPNKIGKLN EETTKNRVQL SGEQERTENS REQAQFRDGS ACESPAFQGN 480 SSIGPNCTAF NASPPYRLRS KRTAVFKSVE RQLEFAFDKE RHEDSMKSSN LLVNGSSSIE 540 DCLHATKMEV T*

Sequence ? help Back to Top

Protein Sequence Length: 552 aa Download sequence Send to blast

MTELKIEERC LENKQLTTAS SSSVSEGGGS AIVKSPATSS PAPTSPNHRR TTGPIRRAKG  60
GWTPEEDETL RNAVATFKGK SWKKIAEFFP DRSEVQCLHR WQKVLNPDLV KGPWTQEEDD  120
KIVELVSKYG PTKWSVIAKS LPGRIGKQCR ERWHNHLNPD IKKDAWTLEE ELALMNAHRI  180
YGNKWAEIAK VLPGRTDNAI KNHWNSSMKK KLDFYLATGK LPPVVKIVLK NEIKDIETPA  240
ATENLLVCSK KESDSTAQTS SGTFDICKPE EDGKDQLESS TPVQDMAATS SIIPSESVET  300
ESAEFKPQSF DANPCSCNSV SMVKFESRRT SSAIVEDKVV ETQLRSDTPT YGPLCYEPPR  360
LQGGTSLDSD NLNKKGMQHE WTITPITSPL SFFTPPCVKG SGFGTQSPES ILRIAAKTFP  420
STPSIFRKRK TSPNKIGKLN EETTKNRVQL SGEQERTENS REQAQFRDGS ACESPAFQGN  480
SSIGPNCTAF NASPPYRLRS KRTAVFKSVE RQLEFAFDKE RHEDSMKSSN LLVNGSSSIE  540
DCLHATKMEV T*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h88_C	1e-68	58	212	5	159	MYB PROTO-ONCOGENE PROTEIN
1h89_C	1e-68	58	212	5	159	MYB PROTO-ONCOGENE PROTEIN
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Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed both in proliferating and maturing stages of leaves. {ECO:0000269\|PubMed:26069325}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds 5'-AACGG-3' motifs in gene promoters (By similarity). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325). {ECO:0000250\|UniProtKB:Q94FL9, ECO:0000269\|PubMed:26069325}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00482	DAP	Transfer from AT5G02320	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Slightly induced by ethylene and salicylic acid (SA). {ECO:0000269\|PubMed:16463103}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012486072.1	0.0	PREDICTED: myb-related protein B-like
Swissprot	Q6R032	1e-170	MB3R5_ARATH; Transcription factor MYB3R-5
TrEMBL	A0A0D2QBQ2	0.0	A0A0D2QBQ2_GOSRA; Uncharacterized protein
STRING	Gorai.006G172800.1	0.0	(Gossypium raimondii)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G02320.2	1e-161	myb domain protein 3r-5

Link Out ? help Back to Top
Phytozome	Gorai.006G172800.2
Entrez Gene	105799845

Publications ? help Back to Top
Paterson AH, et al. Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature, 2012. 492(7429): p. 423-7 [PMID:23257886] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325] Chen P, et al. Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage. Nat Commun, 2017. 8(1): p. 635 [PMID:28935922]