PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

Whirly

Protein Properties

Length: 219aa MW: 23836.1 Da PI: 9.3906

Description

Whirly family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gorai.004G266000.3	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Whirly	176.4	6e-55	74	211	2	137
Whirly 2 vyktkaalkvkavrptfealds..gnlklkraGglllelanataerkydWekkqsfalsatevaelvdlaskesceffhdpaakgsneGkv 90 +yk+ka+l++ +v+ptf+++ds g lk++r+G+++l++ +a++erkydWe++q+fals+tev++l+++++++++ef+hdp++k+sn+G+v Gorai.004G266000.3 74 IYKGKASLSISPVLPTFVKIDSdiGGLKVNRRGSMMLTFCPAIGERKYDWEQRQKFALSPTEVGSLISMGAHDASEFYHDPSMKSSNAGQV 164 9*****************9944679************************************************************ PP Whirly 91 rkalkvePlpdGsGlfvnlsvtnslvkgnesfsvPvskaefavlrsl 137 k l ++ + G G++++l+vtn+++k+ne+f +Pv+ aefavl+++ Gorai.004G266000.3 165 SKKLCIKAFDSGNGYMISLTVTNNILKSNEQFNIPVTTAEFAVLKTA 211 *******************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.30.31.10	6.0E-58	61	213	IPR009044	ssDNA-binding transcriptional regulator
SuperFamily	SSF54447	4.24E-51	65	214	IPR009044	ssDNA-binding transcriptional regulator
Pfam	PF08536	8.1E-53	74	210	IPR013742	Plant transcription factor

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006281	Biological Process	DNA repair
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005739	Cellular Component	mitochondrion
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 219 aa Download sequence Send to blast
MVHSVISGNN QSNIPVNPRT YTKMLKQCRS LLSRSLQSAK WGDGFESRAA FSTSLQDFAA 60 TGNANGRVFA PYTIYKGKAS LSISPVLPTF VKIDSDIGGL KVNRRGSMML TFCPAIGERK 120 YDWEQRQKFA LSPTEVGSLI SMGAHDASEF YHDPSMKSSN AGQVSKKLCI KAFDSGNGYM 180 ISLTVTNNIL KSNEQFNIPV TTAEFAVLKT ACSVCYDD*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4kop_A	5e-74	65	215	8	156	Single-stranded DNA-binding protein WHY2, mitochondrial
4kop_B	5e-74	65	215	8	156	Single-stranded DNA-binding protein WHY2, mitochondrial
4kop_C	5e-74	65	215	8	156	Single-stranded DNA-binding protein WHY2, mitochondrial
4kop_D	5e-74	65	215	8	156	Single-stranded DNA-binding protein WHY2, mitochondrial
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Single-stranded DNA-binding protein that associates with mitochondrial DNA and may play a role in the regulation of the gene expression machinery. Seems also to be required to prevent break-induced DNA rearrangements in the mitochondrial genome. Can bind to melt double-stranded DNA in vivo. {ECO:0000269\|PubMed:18423020, ECO:0000269\|PubMed:20551348, ECO:0000269\|PubMed:22762281}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012476966.1	1e-139	PREDICTED: single-stranded DNA-bindig protein WHY2, mitochondrial
Swissprot	Q8VYF7	5e-78	WHY2_ARATH; Single-stranded DNA-binding protein WHY2, mitochondrial
TrEMBL	A0A0D2RB90	1e-162	A0A0D2RB90_GOSRA; Uncharacterized protein
STRING	Gorai.004G266000.1	1e-157	(Gossypium raimondii)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G71260.1	1e-75	WHIRLY 2

Link Out ? help Back to Top
Phytozome	Gorai.004G266000.3

Publications ? help Back to Top
Paterson AH, et al. Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature, 2012. 492(7429): p. 423-7 [PMID:23257886]