PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

Nin-like

Protein Properties

Length: 987aa MW: 108563 Da PI: 5.7752

Description

Nin-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gorai.004G131700.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	RWP-RK	90.3	1.5e-28	580	630	2	52
RWP-RK 2 ekeisledlskyFslpikdAAkeLgvclTvLKriCRqyGIkRWPhRkiksl 52 ek+isle+l++yF +++k+AAk+Lgvc+T++KriCRq+GI+RWP+Rki+++ Gorai.004G131700.1 580 EKSISLEVLQQYFTGSLKNAAKSLGVCPTTMKRICRQHGISRWPSRKINKV 630 799**********************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51519	17.188	565	650	IPR003035	RWP-RK domain
Pfam	PF02042	1.5E-25	583	630	IPR003035	RWP-RK domain
SuperFamily	SSF54277	2.81E-22	884	974	No hit	No description
PROSITE profile	PS51745	22.172	890	972	IPR000270	PB1 domain
SMART	SM00666	4.2E-23	890	972	IPR000270	PB1 domain
Gene3D	G3DSA:3.10.20.240	4.2E-25	890	972	No hit	No description
Pfam	PF00564	1.7E-15	891	971	IPR000270	PB1 domain
CDD	cd06407	1.61E-37	891	971	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009414	Biological Process	response to water deprivation
GO:0010118	Biological Process	stomatal movement
GO:0010167	Biological Process	response to nitrate
GO:0042128	Biological Process	nitrate assimilation
GO:0005634	Cellular Component	nucleus
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 987 aa Download sequence Send to blast
MCEPEEDNAC PFPPKQLQPQ HQGIMDFDDL DLQSSWPFDQ LTFLSNPTSP FVTSSSSEQP 60 CSPLWAFSDD DKLGSAAAAG YNLFVTCTPN PVNENAKEEN DNRGLPSLFL GLLPLENPDS 120 YCVIKERMTR ALRYFKESTE QHVLAQVWAP VKDGGRYVLT TLGQPFVLDP HSSGLHQYRM 180 VSLMYMFSVD GESDVQLGLP GRVFRQKLPE WTPNVQYYSS REYSRLNHAL HYNVQGTLAL 240 PIFEPSGQSC VGVLELIMTS QKINYAPEVD KVCKALEAVN LKSSEILGYP STQICNESRQ 300 NALAEILEIL TVVCETHKLP LAQTWVPCRH RKVLVHGGGL KKSCTSFDGS CMGQVCMSTT 360 DVAFYVVDAH MWGFRDACLE HHLQKGQGVA GRAFLSLNSC FCSDITQFCK TEYPLVHYAR 420 MFKLTSCFAI CLRSTYTRDD DYVLEFFLPP AIADCNEQHA LLGSILTTMK QHFQSLMVAS 480 GAELEEDEGS IEIIGASSEE RFVTRLECIP IPPPVKSPPK NNTSPNKGEL QLDSSKQQLT 540 VNFDPSAHGG RVVASGSHNL DCPLQNKDLK KPERKRGKTE KSISLEVLQQ YFTGSLKNAA 600 KSLGVCPTTM KRICRQHGIS RWPSRKINKV NRSLTKLKHV IESVHGTDGA FGLTSLANSP 660 LPVGVGSISW PTGLNGSNQQ NSPNSRPFEH KGEKNDSPTC LTPQSNGQVV VEDQLLGGTT 720 LSPEPFPQQN GLSSHFDKGV KRSRRGSTSR EESAGTPISY SSCQGSLGIE NAATKASFGS 780 IHDQCLKAHG SPELAFQQLL GEPNISAMFS MPKVLVAAEL EEPIGGMLVE AAGSSKDLRN 840 LCPIADIGVN EQFPESSWTP PPCSDLALKQ AMSTFTQPTP RVTAREETKS VTIKATYRED 900 IIRFRISMSS GILELKEEVA NRLKLEVGAC DIKYLDDDNE WVLMACDADL EECIDVSRSS 960 GNNIIRLCIH DTMANLESSC ESTGEL*

Sequence ? help Back to Top

Protein Sequence Length: 987 aa Download sequence Send to blast

MCEPEEDNAC PFPPKQLQPQ HQGIMDFDDL DLQSSWPFDQ LTFLSNPTSP FVTSSSSEQP  60
CSPLWAFSDD DKLGSAAAAG YNLFVTCTPN PVNENAKEEN DNRGLPSLFL GLLPLENPDS  120
YCVIKERMTR ALRYFKESTE QHVLAQVWAP VKDGGRYVLT TLGQPFVLDP HSSGLHQYRM  180
VSLMYMFSVD GESDVQLGLP GRVFRQKLPE WTPNVQYYSS REYSRLNHAL HYNVQGTLAL  240
PIFEPSGQSC VGVLELIMTS QKINYAPEVD KVCKALEAVN LKSSEILGYP STQICNESRQ  300
NALAEILEIL TVVCETHKLP LAQTWVPCRH RKVLVHGGGL KKSCTSFDGS CMGQVCMSTT  360
DVAFYVVDAH MWGFRDACLE HHLQKGQGVA GRAFLSLNSC FCSDITQFCK TEYPLVHYAR  420
MFKLTSCFAI CLRSTYTRDD DYVLEFFLPP AIADCNEQHA LLGSILTTMK QHFQSLMVAS  480
GAELEEDEGS IEIIGASSEE RFVTRLECIP IPPPVKSPPK NNTSPNKGEL QLDSSKQQLT  540
VNFDPSAHGG RVVASGSHNL DCPLQNKDLK KPERKRGKTE KSISLEVLQQ YFTGSLKNAA  600
KSLGVCPTTM KRICRQHGIS RWPSRKINKV NRSLTKLKHV IESVHGTDGA FGLTSLANSP  660
LPVGVGSISW PTGLNGSNQQ NSPNSRPFEH KGEKNDSPTC LTPQSNGQVV VEDQLLGGTT  720
LSPEPFPQQN GLSSHFDKGV KRSRRGSTSR EESAGTPISY SSCQGSLGIE NAATKASFGS  780
IHDQCLKAHG SPELAFQQLL GEPNISAMFS MPKVLVAAEL EEPIGGMLVE AAGSSKDLRN  840
LCPIADIGVN EQFPESSWTP PPCSDLALKQ AMSTFTQPTP RVTAREETKS VTIKATYRED  900
IIRFRISMSS GILELKEEVA NRLKLEVGAC DIKYLDDDNE WVLMACDADL EECIDVSRSS  960
GNNIIRLCIH DTMANLESSC ESTGEL*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, stems, leaves, flowers and siliques. Detected in root hairs, emerging secondary roots, vascular tissues, leaf parenchyma cells and stomata. {ECO:0000269\|PubMed:18826430}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in regulation of nitrate assimilation and in transduction of the nitrate signal. {ECO:0000269\|PubMed:18826430}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00449	DAP	Transfer from AT4G24020	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not regulated by the N source or by nitrate. {ECO:0000269\|PubMed:18826430}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012474812.1	0.0	PREDICTED: protein NLP6
Swissprot	Q84TH9	0.0	NLP7_ARATH; Protein NLP7
TrEMBL	A0A0D2RYP3	0.0	A0A0D2RYP3_GOSRA; Uncharacterized protein
STRING	Gorai.004G131700.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2507	26	66

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G24020.1	0.0	NIN like protein 7

Link Out ? help Back to Top
Phytozome	Gorai.004G131700.1
Entrez Gene	105791329

Publications ? help Back to Top
Paterson AH, et al. Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature, 2012. 492(7429): p. 423-7 [PMID:23257886] Xu N, et al. The Arabidopsis NRG2 Protein Mediates Nitrate Signaling and Interacts with and Regulates Key Nitrate Regulators. Plant Cell, 2016. 28(2): p. 485-504 [PMID:26744214] Karve R,Suárez-Román F,Iyer-Pascuzzi AS The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release. Plant Physiol., 2016. 171(3): p. 2101-11 [PMID:27221617] Yu LH, et al. Overexpression of Arabidopsis NLP7 improves plant growth under both nitrogen-limiting and -sufficient conditions by enhancing nitrogen and carbon assimilation. Sci Rep, 2016. 6: p. 27795 [PMID:27293103] Menz J,Li Z,Schulze WX,Ludewig U Early nitrogen-deprivation responses in Arabidopsis roots reveal distinct differences on transcriptome and (phospho-) proteome levels between nitrate and ammonium nutrition. Plant J., 2016. 88(5): p. 717-734 [PMID:27419465] Yan D, et al. NIN-like protein 8 is a master regulator of nitrate-promoted seed germination in Arabidopsis. Nat Commun, 2016. 7: p. 13179 [PMID:27731416] Guan P, et al. Interacting TCP and NLP transcription factors control plant responses to nitrate availability. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(9): p. 2419-2424 [PMID:28202720] Liu KH, et al. Discovery of nitrate-CPK-NLP signalling in central nutrient-growth networks. Nature, 2017. 545(7654): p. 311-316 [PMID:28489820] Li Z, et al. The Arabidopsis CPSF30-L gene plays an essential role in nitrate signaling and regulates the nitrate transceptor gene NRT1.1. New Phytol., 2017. 216(4): p. 1205-1222 [PMID:28850721] Cao H, et al. Overexpression of the Maize ZmNLP6 and ZmNLP8 Can Complement the Arabidopsis Nitrate Regulatory Mutant nlp7 by Restoring Nitrate Signaling and Assimilation. Front Plant Sci, 2017. 8: p. 1703 [PMID:29051766] Konishi N,Okubo T,Yamaya T,Hayakawa T,Minamisawa K Nitrate Supply-Dependent Shifts in Communities of Root-Associated Bacteria in Arabidopsis. Microbes Environ., 2017. 32(4): p. 314-323 [PMID:29187692] Karve RA,Iyer-Pascuzzi AS Further insights into the role of NIN-LIKE PROTEIN 7 (NLP7) in root cap cell release. Plant Signal Behav, 2018. 13(1): p. e1414122 [PMID:29215953] Zhao L, et al. The Arabidopsis NLP7 gene regulates nitrate signaling via NRT1.1-dependent pathway in the presence of ammonium. Sci Rep, 2018. 8(1): p. 1487 [PMID:29367694]