PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

ERF

Protein Properties

Length: 226aa MW: 25090.8 Da PI: 8.835

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gorai.004G032500.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	62.4	1e-19	29	78	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr ++ +gr++AeIrdp + ++r++lg+f++aeeAa+a++aa+ l+g Gorai.004G032500.1 29 RYRGVRKRP-WGRFAAEIRDPLK---KTRVWLGTFDSAEEAARAYDAAAITLRG 78 69*****.******743...5***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	1.74E-18	28	86	No hit	No description
PROSITE profile	PS51032	24.131	29	86	IPR001471	AP2/ERF domain
SMART	SM00380	6.1E-38	29	92	IPR001471	AP2/ERF domain
Pfam	PF00847	7.3E-14	29	78	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	9.81E-23	29	87	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	2.9E-32	29	86	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.7E-11	30	41	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.7E-11	52	68	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 226 aa Download sequence Send to blast
MRKGRGAAAA ADTAMKPAVE ANGSVKEQRY RGVRKRPWGR FAAEIRDPLK KTRVWLGTFD 60 SAEEAARAYD AAAITLRGNK AKTNFPFNSS DFPAFGIDRH HRRNNEGFIA DGHRLHQTGG 120 DYEDPEVNPQ RPARSSMSST VESFSGPRPT QPPRKPSDFE AVSTRKYHPK MPRTAPEDCR 180 SDCDSSSSVF DNGDDDNVSS SRRKFLPFDL NFPPLDEVDD LTLCL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	5e-21	29	86	14	72	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as a transcriptional repressor. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways and could also regulate other AtERFs. {ECO:0000269\|PubMed:10715325, ECO:0000269\|PubMed:11487705, ECO:0000269\|PubMed:9756931}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by jasmonate (JA), ethylene and Alternaria brassicicola (locally and systemically). Moderate induction by wounding or drought stress does not require EIN2, whereas induction by NaCl does. Transcripts accumulate slightly in cycloheximide-treated plants, a protein synthesis inhibitor. Seems to not be influenced by ethylene, exogenous abscisic acid (ABA), cold and heat stress. {ECO:0000269\|PubMed:10715325, ECO:0000269\|PubMed:12805630}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	DQ116447	0.0	DQ116447.1 Gossypium hirsutum ethylene-responsive element-binding factor (ERF3) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012473192.1	1e-166	PREDICTED: ethylene-responsive transcription factor 3-like
Swissprot	O80339	5e-47	ERF82_ARATH; Ethylene-responsive transcription factor 3
TrEMBL	A0A0D2RSP7	1e-164	A0A0D2RSP7_GOSRA; Uncharacterized protein
STRING	Gorai.004G032500.1	1e-165	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM10	28	1650

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G20310.1	1e-38	ethylene response factor 7

Link Out ? help Back to Top
Phytozome	Gorai.004G032500.1
Entrez Gene	105790241

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Paterson AH, et al. Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature, 2012. 492(7429): p. 423-7 [PMID:23257886] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444]