PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

Nin-like

Protein Properties

Length: 707aa MW: 77113.2 Da PI: 6.7042

Description

Nin-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gorai.003G074300.4	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	RWP-RK	92.6	2.9e-29	305	355	2	52
RWP-RK 2 ekeisledlskyFslpikdAAkeLgvclTvLKriCRqyGIkRWPhRkiksl 52 ek+isle+l++yF++++kdAAk+Lgvc+T++KriCRq+GI+RWP+Rki+++ Gorai.003G074300.4 305 EKSISLEVLQQYFAGSLKDAAKSLGVCPTTMKRICRQHGISRWPSRKINKV 355 799**********************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51519	17.894	290	375	IPR003035	RWP-RK domain
Pfam	PF02042	2.5E-26	308	355	IPR003035	RWP-RK domain
SuperFamily	SSF54277	4.25E-24	606	695	No hit	No description
SMART	SM00666	1.2E-26	610	692	IPR000270	PB1 domain
PROSITE profile	PS51745	26.356	610	692	IPR000270	PB1 domain
Gene3D	G3DSA:3.10.20.240	1.2E-28	610	692	No hit	No description
Pfam	PF00564	9.1E-19	611	691	IPR000270	PB1 domain
CDD	cd06407	1.41E-39	611	691	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 707 aa Download sequence Send to blast
MQAANLKSSE ILDHPSTKIC NKSRQNALAE ILEILTMVCE THKLPLAQTW VPCRHRNVLA 60 HGGGSKKYCT SFDGSCMGQV CISTTDVAFY VVDAHMWGFR EACLEHHLQK GQGVSGRAFL 120 SHNPCFCADI TQFCKTEYPL VHYARMFGLT SCFAICLQST YTGDDDYVLE FFLPPAIADF 180 NEQQTLLGSI LSTIKQHFQC IKVAPGTKLK ENKGSIEIII ASSDERLSSR LEFIPISPSV 240 KSPPGTNSSP NRGDLQIDSL RKQLSDNHDP ATDGSKVVAS GSQDPVCLPK NEELKKPERK 300 RGKTEKSISL EVLQQYFAGS LKDAAKSLGV CPTTMKRICR QHGISRWPSR KINKVNRSLT 360 KLKHVIESVQ GADEAFDLTS LATSPLPVAV GSISWTTGLN GSHQQNLTNS KPSEPQVDKN 420 DLPTCQMPGS NTQVLVDDQL LGGRTLIQEQ LFSHHNGLSP SLDKGANRFK TGSGSRDESA 480 GTPTSHGSCQ GSPATESAAT KDPLGFSHDQ CSPKLAFHLE ELNISTSFSM PEAPVTAEPR 540 EPFGGMLVED AGSSKDLRNL CPIVAEIGAD ERLPESSWTP PQCSELGIKH TMHTFTQTTP 600 HVTARHGMKS VTIKATYRED IIRFRISLSS GIVELKEEVA KRLKLEVGTF DIKYLDDDNE 660 WVLIACDADL QECLDVSRSS GSNIIRLSVH DTVANLGSSC ESTGEL*

Sequence ? help Back to Top

Protein Sequence Length: 707 aa Download sequence Send to blast

MQAANLKSSE ILDHPSTKIC NKSRQNALAE ILEILTMVCE THKLPLAQTW VPCRHRNVLA  60
HGGGSKKYCT SFDGSCMGQV CISTTDVAFY VVDAHMWGFR EACLEHHLQK GQGVSGRAFL  120
SHNPCFCADI TQFCKTEYPL VHYARMFGLT SCFAICLQST YTGDDDYVLE FFLPPAIADF  180
NEQQTLLGSI LSTIKQHFQC IKVAPGTKLK ENKGSIEIII ASSDERLSSR LEFIPISPSV  240
KSPPGTNSSP NRGDLQIDSL RKQLSDNHDP ATDGSKVVAS GSQDPVCLPK NEELKKPERK  300
RGKTEKSISL EVLQQYFAGS LKDAAKSLGV CPTTMKRICR QHGISRWPSR KINKVNRSLT  360
KLKHVIESVQ GADEAFDLTS LATSPLPVAV GSISWTTGLN GSHQQNLTNS KPSEPQVDKN  420
DLPTCQMPGS NTQVLVDDQL LGGRTLIQEQ LFSHHNGLSP SLDKGANRFK TGSGSRDESA  480
GTPTSHGSCQ GSPATESAAT KDPLGFSHDQ CSPKLAFHLE ELNISTSFSM PEAPVTAEPR  540
EPFGGMLVED AGSSKDLRNL CPIVAEIGAD ERLPESSWTP PQCSELGIKH TMHTFTQTTP  600
HVTARHGMKS VTIKATYRED IIRFRISLSS GIVELKEEVA KRLKLEVGTF DIKYLDDDNE  660
WVLIACDADL QECLDVSRSS GSNIIRLSVH DTVANLGSSC ESTGEL*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, stems, leaves, flowers and siliques. Detected in root hairs, emerging secondary roots, vascular tissues, leaf parenchyma cells and stomata. {ECO:0000269\|PubMed:18826430}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in regulation of nitrate assimilation and in transduction of the nitrate signal. {ECO:0000269\|PubMed:18826430}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not regulated by the N source or by nitrate. {ECO:0000269\|PubMed:18826430}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012470366.1	0.0	PREDICTED: protein NLP6-like isoform X1
Swissprot	Q84TH9	0.0	NLP7_ARATH; Protein NLP7
TrEMBL	A0A0D2NXT4	0.0	A0A0D2NXT4_GOSRA; Uncharacterized protein
STRING	Gorai.003G074300.1	0.0	(Gossypium raimondii)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G24020.1	0.0	NIN like protein 7

Link Out ? help Back to Top
Phytozome	Gorai.003G074300.4

Publications ? help Back to Top
Paterson AH, et al. Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature, 2012. 492(7429): p. 423-7 [PMID:23257886] Xu N, et al. The Arabidopsis NRG2 Protein Mediates Nitrate Signaling and Interacts with and Regulates Key Nitrate Regulators. Plant Cell, 2016. 28(2): p. 485-504 [PMID:26744214] Karve R,Suárez-Román F,Iyer-Pascuzzi AS The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release. Plant Physiol., 2016. 171(3): p. 2101-11 [PMID:27221617] Yu LH, et al. Overexpression of Arabidopsis NLP7 improves plant growth under both nitrogen-limiting and -sufficient conditions by enhancing nitrogen and carbon assimilation. Sci Rep, 2016. 6: p. 27795 [PMID:27293103] Menz J,Li Z,Schulze WX,Ludewig U Early nitrogen-deprivation responses in Arabidopsis roots reveal distinct differences on transcriptome and (phospho-) proteome levels between nitrate and ammonium nutrition. Plant J., 2016. 88(5): p. 717-734 [PMID:27419465] Yan D, et al. NIN-like protein 8 is a master regulator of nitrate-promoted seed germination in Arabidopsis. Nat Commun, 2016. 7: p. 13179 [PMID:27731416] Guan P, et al. Interacting TCP and NLP transcription factors control plant responses to nitrate availability. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(9): p. 2419-2424 [PMID:28202720] Liu KH, et al. Discovery of nitrate-CPK-NLP signalling in central nutrient-growth networks. Nature, 2017. 545(7654): p. 311-316 [PMID:28489820] Li Z, et al. The Arabidopsis CPSF30-L gene plays an essential role in nitrate signaling and regulates the nitrate transceptor gene NRT1.1. New Phytol., 2017. 216(4): p. 1205-1222 [PMID:28850721] Cao H, et al. Overexpression of the Maize ZmNLP6 and ZmNLP8 Can Complement the Arabidopsis Nitrate Regulatory Mutant nlp7 by Restoring Nitrate Signaling and Assimilation. Front Plant Sci, 2017. 8: p. 1703 [PMID:29051766] Konishi N,Okubo T,Yamaya T,Hayakawa T,Minamisawa K Nitrate Supply-Dependent Shifts in Communities of Root-Associated Bacteria in Arabidopsis. Microbes Environ., 2017. 32(4): p. 314-323 [PMID:29187692] Karve RA,Iyer-Pascuzzi AS Further insights into the role of NIN-LIKE PROTEIN 7 (NLP7) in root cap cell release. Plant Signal Behav, 2018. 13(1): p. e1414122 [PMID:29215953] Zhao L, et al. The Arabidopsis NLP7 gene regulates nitrate signaling via NRT1.1-dependent pathway in the presence of ammonium. Sci Rep, 2018. 8(1): p. 1487 [PMID:29367694]