PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

C2H2

Protein Properties

Length: 251aa MW: 27063.3 Da PI: 4.9403

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gorai.001G196800.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	12.9	0.00033	88	110	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C + F ++ L H++ H Gorai.001G196800.1 88 FSCNYCQRKFFSSQALGGHQNAH 110 89*****************9988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	3.58E-6	86	115	No hit	No description
PROSITE profile	PS50157	11.344	88	115	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	90	110	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0044212	Molecular Function	transcription regulatory region DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 251 aa Download sequence Send to blast
MKPIIDLEVD APETESDVSS QVASNLYTQE ASVAPSNETN LEPVSLDLTL CFNIDGRDSV 60 GLSFTSTSES SNIDPALRTT ASAIPRVFSC NYCQRKFFSS QALGGHQNAH KRERTLAKRA 120 MRMGIFSDRY ASLSLATLPL HGMATSFRSL GIKAHCLAHQ SFAPATRTPD TRNNAIVEHG 180 YLGLPIFMED DEAELLWPGS FRQIAQAAAG GSNADHPGFV LPGSSNMNFV EVKEPVDLED 240 SSAPDLTLKL *

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as negative regulator of abscisic acid (ABA) signaling during germination and early seedling development. {ECO:0000269\|PubMed:24808098}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012486802.1	0.0	PREDICTED: zinc finger protein 4
Refseq	XP_016745918.1	0.0	PREDICTED: zinc finger protein 4
Refseq	XP_016745919.1	0.0	PREDICTED: zinc finger protein 4
Swissprot	Q39263	1e-55	ZFP4_ARATH; Zinc finger protein 4
TrEMBL	A0A0D2QSY4	0.0	A0A0D2QSY4_GOSRA; Uncharacterized protein
TrEMBL	A0A1U8P6R0	0.0	A0A1U8P6R0_GOSHI; zinc finger protein 4
STRING	Gorai.001G196800.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6672	26	43

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G66140.1	4e-58	zinc finger protein 4

Link Out ? help Back to Top
Phytozome	Gorai.001G196800.1
Entrez Gene	105800307

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Paterson AH, et al. Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature, 2012. 492(7429): p. 423-7 [PMID:23257886] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Joseph MP, et al. The Arabidopsis ZINC FINGER PROTEIN3 Interferes with Abscisic Acid and Light Signaling in Seed Germination and Plant Development. Plant Physiol., 2014. 165(3): p. 1203-1220 [PMID:24808098] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470]