PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

C2H2

Protein Properties

Length: 263aa MW: 28446.6 Da PI: 9.2591

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gorai.001G036700.3	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	13.5	0.00021	82	104	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C + F ++ L H++ H Gorai.001G036700.3 82 FSCNYCQRKFYSSQALGGHQNAH 104 89*****************9988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	1.25E-6	79	109	No hit	No description
PROSITE profile	PS50157	11.427	82	109	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	84	104	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 263 aa Download sequence Send to blast
MESVRKEPSP SESTSCVISA PDAPSISDEQ LKKPKPRLQL DLKLSTSDSD VPAFNFNQEL 60 NLIGSLNTPE TPQPADSEQR VFSCNYCQRK FYSSQALGGH QNAHKRERTL AKRAQRIGVH 120 AAFGGHPYFH HNHCSSLASF PLQGPHNRSL GIEVHSSMIH EPSRMISSSA GFGNVYGHPS 180 WSRLPINQQP AIGKLSTENS HAISRPGSTS RASLGRFDNV MRSRMMGLGS SADDGQVIGN 240 SWWSNGGGGG GSLNRKTELQ EG*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in the chalaze of seeds, hypocotyls, cotyledons, roots, emerging lateral roots, leaves, sepals and stamens. These data suggest that ZFP3 is expressed in most organs, showing high expression in vascular tissues.

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as negative regulator of abscisic acid (ABA) signaling during germination and early seedling development. Involved in the regulation of vegetative development and fertility. Modulates red light signaling in seedling photomorphogenesis. {ECO:0000269\|PubMed:24808098}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by abscisic acid (ABA). {ECO:0000269\|PubMed:24808098}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JX614801	1e-130	JX614801.1 Gossypium hirsutum clone NBRI_GE58454 microsatellite sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012449746.1	0.0	PREDICTED: zinc finger protein 3 isoform X1
Swissprot	Q39262	3e-40	ZFP3_ARATH; Zinc finger protein 3
TrEMBL	A0A0D2QK82	0.0	A0A0D2QK82_GOSRA; Uncharacterized protein
STRING	Gorai.001G036700.1	0.0	(Gossypium raimondii)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G10970.1	2e-50	C2H2 family protein

Link Out ? help Back to Top
Phytozome	Gorai.001G036700.3

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Paterson AH, et al. Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature, 2012. 492(7429): p. 423-7 [PMID:23257886] Joseph MP, et al. The Arabidopsis ZINC FINGER PROTEIN3 Interferes with Abscisic Acid and Light Signaling in Seed Germination and Plant Development. Plant Physiol., 2014. 165(3): p. 1203-1220 [PMID:24808098] Zhang A, et al. The Arabidopsis Gene zinc finger protein 3(ZFP3) Is Involved in Salt Stress and Osmotic Stress Response. PLoS ONE, 2016. 11(12): p. e0168367 [PMID:27977750]