PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja

Family

C2H2

Protein Properties

Length: 536aa MW: 58395.9 Da PI: 7.8253

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Glyma.19G208900.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.1	1.5e-05	85	107	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H Glyma.19G208900.1.p 85 FVCEICNKGFQRDQNLQLHRRGH 107 89*******************88 PP
2	zf-C2H2	16.1	3.1e-05	161	183	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k++ +s+ k H++t+ Glyma.19G208900.1.p 161 WKCDKCSKRYAVQSDWKAHQKTC 183 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	4.7E-8	84	107	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.8E-5	84	107	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
Pfam	PF12171	8.6E-5	85	107	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE profile	PS50157	10.949	85	107	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.017	85	107	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	87	107	IPR007087	Zinc finger, C2H2
SMART	SM00355	75	126	156	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	8.9E-6	149	182	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	4.7E-8	156	182	No hit	No description
SMART	SM00355	89	161	181	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 536 aa Download sequence Send to blast
MSNISGDEGS FSSGNNGEEV HQESQQQHLQ SQLHDSSSGP SGACNSNASS NQQQTKKKRN 60 LPGTPDPNAE VVALSPTTLM ATNRFVCEIC NKGFQRDQNL QLHRRGHNLP WKLRQRTSTE 120 VKKRVYVCPE PSCVHHNPAR ALGDLTGIKK HYSRKHGEKK WKCDKCSKRY AVQSDWKAHQ 180 KTCGTREYKC DCGTIFSRRD SFITHRAFCD ALTEENNRVN NQGLTSGMPP NLQSQIPDLM 240 STMPLTTSPN TASKFGEYDP KNPLKSLAQE LVPIPFKFMS MGGGMFSTNA GALFGGPKTM 300 SPSSSSLQLG SSTSSSFNYL QDSENGGLIA ASAQMSATAL LQKAAQMGAT ASNSINSPMM 360 QKGFVSGTTT GPDHVSSTTR PPYSGAMLQH NNSYDHFSPQ PDLSSMAEVS GGGAFINQLF 420 HKGQEISQVF DTNNPGSAMN DVGMFGQMPM GRDHHNQGLM KSVEQEVSNS SSLMHGRDVN 480 DGNHPMQPST RFGGSDMTTV HDFLGIGGST SRVMNHFHHH FPHEDSTIEE PMWDV*

Sequence ? help Back to Top

Protein Sequence Length: 536 aa Download sequence Send to blast

MSNISGDEGS FSSGNNGEEV HQESQQQHLQ SQLHDSSSGP SGACNSNASS NQQQTKKKRN  60
LPGTPDPNAE VVALSPTTLM ATNRFVCEIC NKGFQRDQNL QLHRRGHNLP WKLRQRTSTE  120
VKKRVYVCPE PSCVHHNPAR ALGDLTGIKK HYSRKHGEKK WKCDKCSKRY AVQSDWKAHQ  180
KTCGTREYKC DCGTIFSRRD SFITHRAFCD ALTEENNRVN NQGLTSGMPP NLQSQIPDLM  240
STMPLTTSPN TASKFGEYDP KNPLKSLAQE LVPIPFKFMS MGGGMFSTNA GALFGGPKTM  300
SPSSSSLQLG SSTSSSFNYL QDSENGGLIA ASAQMSATAL LQKAAQMGAT ASNSINSPMM  360
QKGFVSGTTT GPDHVSSTTR PPYSGAMLQH NNSYDHFSPQ PDLSSMAEVS GGGAFINQLF  420
HKGQEISQVF DTNNPGSAMN DVGMFGQMPM GRDHHNQGLM KSVEQEVSNS SSLMHGRDVN  480
DGNHPMQPST RFGGSDMTTV HDFLGIGGST SRVMNHFHHH FPHEDSTIEE PMWDV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	2e-34	157	221	3	67	Zinc finger protein JACKDAW
5b3h_F	2e-34	157	221	3	67	Zinc finger protein JACKDAW
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Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Observed in vegetative tissues. Mainly expressed in hypocotyls, petioles, shoot apices, root tips, and trichomes, and, at low levels, in leaves, stems and flowers. {ECO:0000269\|PubMed:25035403}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Glyma.19G208900.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC235349	0.0	AC235349.1 Glycine max strain Williams 82 clone GM_WBb0092H01, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028217517.1	0.0	zinc finger protein GAI-ASSOCIATED FACTOR 1-like
Swissprot	Q9SCQ6	1e-114	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A445FJL2	0.0	A0A445FJL2_GLYSO; Protein indeterminate-domain 2
TrEMBL	K7MZH6	0.0	K7MZH6_SOYBN; Uncharacterized protein
STRING	GLYMA19G39640.2	0.0	(Glycine max)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF2192	30	85
Representative plant	OGRP95	16	242

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	1e-112	indeterminate(ID)-domain 2

Link Out ? help Back to Top
Phytozome	Glyma.19G208900.1.p

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]