PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja

Family

MYB

Protein Properties

Length: 362aa MW: 40851.5 Da PI: 9.8992

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Glyma.07G132400.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	49.9	7.3e-16	4	53	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHT..TTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmg..kgRtlkqcksrwqkyl 48 r+rW +eEd ll +vkq+G++ W++++++m+ ++R +k+c +rw +yl Glyma.07G132400.1.p 4 RQRWRAEEDALLRAYVKQYGPREWNLVSQRMNtpLNRDAKSCLERWKNYL 53 89**********************************************97 PP
2	Myb_DNA-binding	34.4	5.2e-11	59	103	1	47
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 +g+ T+eE+ l +++ + +G++ Wk+Ia+ ++ gRt+k + +w + Glyma.07G132400.1.p 59 KGSLTEEEQRLVINLQATHGNK-WKKIAAQVP-GRTAKRLGKWWEVF 103 6788****************.*****.***999999766 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	23.01	1	57	IPR017930	Myb domain
SMART	SM00717	1.1E-13	3	55	IPR001005	SANT/Myb domain
SuperFamily	SSF46689	1.27E-21	4	98	IPR009057	Homeodomain-like
CDD	cd00167	4.74E-9	6	53	No hit	No description
Gene3D	G3DSA:1.10.10.60	1.4E-20	6	60	IPR009057	Homeodomain-like
Pfam	PF13921	3.9E-14	7	67	No hit	No description
PROSITE profile	PS51294	17.822	58	108	IPR017930	Myb domain
SMART	SM00717	1.7E-9	58	106	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	4.7E-15	61	102	IPR009057	Homeodomain-like
CDD	cd00167	2.19E-6	63	104	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0008356	Biological Process	asymmetric cell division
GO:0009615	Biological Process	response to virus
GO:0009651	Biological Process	response to salt stress
GO:0009733	Biological Process	response to auxin
GO:0009739	Biological Process	response to gibberellin
GO:0009751	Biological Process	response to salicylic acid
GO:0009753	Biological Process	response to jasmonic acid
GO:0009944	Biological Process	polarity specification of adaxial/abaxial axis
GO:0010338	Biological Process	leaf formation
GO:0042742	Biological Process	defense response to bacterium
GO:0045088	Biological Process	regulation of innate immune response
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0046686	Biological Process	response to cadmium ion
GO:0050832	Biological Process	defense response to fungus
GO:0000793	Cellular Component	condensed chromosome
GO:0005730	Cellular Component	nucleolus
GO:0003677	Molecular Function	DNA binding
GO:0042803	Molecular Function	protein homodimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 362 aa Download sequence Send to blast
MKDRQRWRAE EDALLRAYVK QYGPREWNLV SQRMNTPLNR DAKSCLERWK NYLKPGIKKG 60 SLTEEEQRLV INLQATHGNK WKKIAAQVPG RTAKRLGKWW EVFKEKQQRE TKGNNCTIDP 120 INDSKYEHIL ESFAEKLVKE RPSTSTSTSF VMATSNSSFL HADAPAPAPA LLPSWLSNSN 180 GTAPVRPPSP SVTLSLSPST VAAPPPWMQP PVRGQDNASP LVLGNVAPHG AVLAFGENMV 240 MSELVECCKE LDEVHHALAG HKKEAAWRLS RVELQLESEK AGRRREKMEE IEAKIKALRE 300 EQTAALDRIE AEYREQLAGL RRDAESKEQK LAEQWAAKHL RLTKFLEQVG CRSRLTEPNG 360 R*

Sequence ? help Back to Top

Protein Sequence Length: 362 aa Download sequence Send to blast

MKDRQRWRAE EDALLRAYVK QYGPREWNLV SQRMNTPLNR DAKSCLERWK NYLKPGIKKG  60
SLTEEEQRLV INLQATHGNK WKKIAAQVPG RTAKRLGKWW EVFKEKQQRE TKGNNCTIDP  120
INDSKYEHIL ESFAEKLVKE RPSTSTSTSF VMATSNSSFL HADAPAPAPA LLPSWLSNSN  180
GTAPVRPPSP SVTLSLSPST VAAPPPWMQP PVRGQDNASP LVLGNVAPHG AVLAFGENMV  240
MSELVECCKE LDEVHHALAG HKKEAAWRLS RVELQLESEK AGRRREKMEE IEAKIKALRE  300
EQTAALDRIE AEYREQLAGL RRDAESKEQK LAEQWAAKHL RLTKFLEQVG CRSRLTEPNG  360
R*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1a5j_A	7e-16	7	92	10	92	B-MYB
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Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Preferential expression in young and immature plant tissues. In embryos, expressed from the late globular stage onwards. After germination, detected in leaf founder cells and on flowering, in primordia of all floral organs.
Uniprot	TISSUE SPECIFICITY: Expressed in roots, stems, leaves, flowers, siliques and in lateral organ promordia (PubMed:17559509). Found in the inner domain between the adaxial and abaxial domains of leaves (PubMed:17559509). Expressed in the phloem tissues of leaves, cotyledons, hypocotyls, and roots (PubMed:21950734). {ECO:0000269\|PubMed:17559509, ECO:0000269\|PubMed:21950734}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor required for normal cell differentiation. Positively regulates LATERAL ORGAN BOUNDARIES (LOB) within the shoot apex, and the class III HD-ZIP genes REV, PHB, and PHV. Interacts directly with ASYMMETRIC LEAVES 2 (LBD6/AS2) to repress the knox homeobox genes BP/KNAT1, KNAT2, and KNAT6 and the abaxial determinants ARF3/ETT, KAN2 and YAB5. May act in parallel with the RDR6-SGS3-AGO7 pathway, an endogenous RNA silencing pathway, to regulate the leaf morphogenesis (PubMed:11076771, PubMed:11140682, PubMed:11882937, PubMed:12750468, PubMed:16006579, PubMed:16699177, PubMed:17395603, PubMed:17559509, PubMed:23271976). Binds directly to KNAT1, KNAT2, and KNATM chromatin, regulating leaf development (PubMed:23271976). LBD6 is required for this binding (PubMed:23271976). Positive regulator of flowering that binds to the promoter of FT (PubMed:21950734). Regulates FT expression by forming a functional complex with CO (PubMed:21950734). Involved in leaf polarity establishment by functioning cooperatively with NUCL1 to repress abaxial genes ARF3, ARF4, KAN1, KAN2, YAB1 and YAB5, and the knox homeobox genes KNAT1, KNAT2, KNAT6, and STM to promote adaxial development in leaf primordia at shoot apical meristems at high temperatures (PubMed:27334696). {ECO:0000269\|PubMed:11076771, ECO:0000269\|PubMed:11140682, ECO:0000269\|PubMed:11882937, ECO:0000269\|PubMed:12750468, ECO:0000269\|PubMed:16006579, ECO:0000269\|PubMed:16699177, ECO:0000269\|PubMed:17395603, ECO:0000269\|PubMed:17559509, ECO:0000269\|PubMed:23271976, ECO:0000269\|PubMed:27334696}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Glyma.07G132400.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian-regulation with an afternoon peak in long days and with a broad night peak in short days (PubMed:21950734). Expression of AS1 in stem cells of the shoot apical meristem is prevented by SHOOT MERISTEMLESS (STM). Expression is activated by GTE6 during leaf morphogenesis (PubMed:16166385). {ECO:0000269\|PubMed:16166385, ECO:0000269\|PubMed:21950734}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KT031259	0.0	KT031259.1 Glycine max clone HN_CCL_76 MYB/HD-like transcription factor (Glyma07g15850.1) mRNA, partial cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006582959.1	0.0	phantastica transcription factor a isoform X1
Refseq	XP_028240296.1	0.0	transcription factor AS1-like
Swissprot	O80931	1e-157	AS1_ARATH; Transcription factor AS1
TrEMBL	A0A0K2CTB2	0.0	A0A0K2CTB2_SOYBN; MYB/HD-like transcription factor (Fragment)
TrEMBL	A0A445JWD3	0.0	A0A445JWD3_GLYSO; Transcription factor AS1
STRING	GLYMA07G15850.1	0.0	(Glycine max)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF2597	33	69
Representative plant	OGRP5096	14	21

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G37630.1	1e-134	MYB family protein

Link Out ? help Back to Top
Phytozome	Glyma.07G132400.1.p
Entrez Gene	732551

Publications ? help Back to Top
Hazen SP, et al. Rapid array mapping of circadian clock and developmental mutations in Arabidopsis. Plant Physiol., 2005. 138(2): p. 990-7 [PMID:15908595] Pinon V, et al. Three PIGGYBACK genes that specifically influence leaf patterning encode ribosomal proteins. Development, 2008. 135(7): p. 1315-24 [PMID:18305008] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zhou F,Roy B,Dunlap JR,Enganti R,von Arnim AG Translational control of Arabidopsis meristem stability and organogenesis by the eukaryotic translation factor eIF3h. PLoS ONE, 2014. 9(4): p. e95396 [PMID:24736281] Scofield S,Dewitte W,Murray JA STM sustains stem cell function in the Arabidopsis shoot apical meristem and controls KNOX gene expression independently of the transcriptional repressor AS1. Plant Signal Behav, 2018. [PMID:24776954] Ivanova A, et al. A Functional Antagonistic Relationship between Auxin and Mitochondrial Retrograde Signaling Regulates Alternative Oxidase1a Expression in Arabidopsis. Plant Physiol., 2014. 165(3): p. 1233-1254 [PMID:24820025] Machida C,Nakagawa A,Kojima S,Takahashi H,Machida Y The complex of ASYMMETRIC LEAVES (AS) proteins plays a central role in antagonistic interactions of genes for leaf polarity specification in Arabidopsis. Wiley Interdiscip Rev Dev Biol, 2015 Nov-Dec. 4(6): p. 655-71 [PMID:26108442] Chai C, et al. Soybean transcription factor ORFeome associated with drought resistance: a valuable resource to accelerate research on abiotic stress resistance. BMC Genomics, 2015. 16: p. 596 [PMID:26268547] Kaurilind E,Xu E,Brosché M A genetic framework for H2O2 induced cell death in Arabidopsis thaliana. BMC Genomics, 2015. 16: p. 837 [PMID:26493993] Mateo-Bonmatí E, et al. Plastid control of abaxial-adaxial patterning. Sci Rep, 2015. 5: p. 15975 [PMID:26522839] Rast-Somssich MI, et al. Alternate wiring of a KNOXI genetic network underlies differences in leaf development of A. thaliana and C. hirsuta. Genes Dev., 2015. 29(22): p. 2391-404 [PMID:26588991] Guzmán-López JA,Abraham-Juárez MJ,Lozano-Sotomayor P,de Folter S,Simpson J Arabidopsis thaliana gonidialess A/Zuotin related factors (GlsA/ZRF) are essential for maintenance of meristem integrity. Plant Mol. Biol., 2016. 91(1-2): p. 37-51 [PMID:26826012] Li Z, et al. Transcription factors AS1 and AS2 interact with LHP1 to repress KNOX genes in Arabidopsis. J Integr Plant Biol, 2016. 58(12): p. 959-970 [PMID:27273574] Matsumura Y, et al. A genetic link between epigenetic repressor AS1-AS2 and a putative small subunit processome in leaf polarity establishment of Arabidopsis. Biol Open, 2016. 5(7): p. 942-54 [PMID:27334696] Silverblatt-Buser EW,Frick MA,Rabeler C,Kaplinsky NJ Genetic Interactions Between BOB1 and Multiple 26S Proteasome Subunits Suggest a Role for Proteostasis in Regulating Arabidopsis Development. G3 (Bethesda), 2018. 8(4): p. 1379-1390 [PMID:29487187] Tsukaya H,Uchimiya H Genetic analyses of the formation of the serrated margin of leaf blades in Arabidopsis: combination of a mutational analysis of leaf morphogenesis with the characterization of a specific marker gene expressed in hydathodes and stipules. Mol. Gen. Genet., 1997. 256(3): p. 231-8 [PMID:9393447]