PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gh_D11G1217

Organism

Gossypium hirsutum

Taxonomic ID

3635

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

C2H2

Protein Properties

Length: 565aa MW: 62047.1 Da PI: 8.6899

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_D11G1217	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17	1.6e-05	103	125	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H Gh_D11G1217 103 FVCEICNKGFQRDQNLQLHRRGH 125 89*******************88 PP
2	zf-C2H2	15.4	5.2e-05	179	201	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k + +s+ k H++t+ Gh_D11G1217 179 WKCDKCSKKYAVQSDWKAHQKTC 201 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	1.9E-5	102	125	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	7.42E-8	102	125	No hit	No description
PROSITE profile	PS50157	10.949	103	125	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.017	103	125	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	105	125	IPR007087	Zinc finger, C2H2
SMART	SM00355	98	144	174	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	6.5E-5	167	200	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	7.42E-8	174	200	No hit	No description
SMART	SM00355	94	179	199	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 565 aa Download sequence Send to blast
MKIKETDKLS TLSLYFLVSS QFQMSKISCD DGSLSSGNTG EEVHQLLLKN NSPPALVSNT 60 NSSSSQHPQP QPPYIIVVLS MKPDPNAEVI ALSPTTLMAT NRFVCEICNK GFQRDQNLQL 120 HRRGHNLPWK LRQRTTTEVK KRVYICPEPT CVHHNPARAL GDLTGIKKHF SRKHGEKKWK 180 CDKCSKKYAV QSDWKAHQKT CGTKEYKCDC GTIFSRRDSF ITHRAFCDAI AEENIKVNQG 240 LMNNAGSNLQ NRMPDLLMSS MPMCNGNTSM EISDFNNFDS KSTPLKSLPQ ELVPMPFKSM 300 NIGGGMFSSS SGTLFGTTRS ISSASSSLQL SSNGSSGFNY LQDTKKGCQI AGSPHMSATA 360 LLQKAAQMGA TASNSINSPI MQTSFASSMA GPDQAITFGG IQQQNTSYDQ FPSQTDQSSM 420 VGISEGFSNQ LKQKSPNEFA QLFQGSSAMN EMGMLTNMLL NGVDRNQGLM KNMEHEGSGS 480 SYNLLQGRKP TGPSIYGTSS GGGNMTTLDF MGIGGLTPTN LHEQQHLQQR LELEAISQQR 540 LPMMNPFQQQ YSHGDSTIEK PIWDV

Sequence ? help Back to Top

Protein Sequence Length: 565 aa Download sequence Send to blast

MKIKETDKLS TLSLYFLVSS QFQMSKISCD DGSLSSGNTG EEVHQLLLKN NSPPALVSNT  60
NSSSSQHPQP QPPYIIVVLS MKPDPNAEVI ALSPTTLMAT NRFVCEICNK GFQRDQNLQL  120
HRRGHNLPWK LRQRTTTEVK KRVYICPEPT CVHHNPARAL GDLTGIKKHF SRKHGEKKWK  180
CDKCSKKYAV QSDWKAHQKT CGTKEYKCDC GTIFSRRDSF ITHRAFCDAI AEENIKVNQG  240
LMNNAGSNLQ NRMPDLLMSS MPMCNGNTSM EISDFNNFDS KSTPLKSLPQ ELVPMPFKSM  300
NIGGGMFSSS SGTLFGTTRS ISSASSSLQL SSNGSSGFNY LQDTKKGCQI AGSPHMSATA  360
LLQKAAQMGA TASNSINSPI MQTSFASSMA GPDQAITFGG IQQQNTSYDQ FPSQTDQSSM  420
VGISEGFSNQ LKQKSPNEFA QLFQGSSAMN EMGMLTNMLL NGVDRNQGLM KNMEHEGSGS  480
SYNLLQGRKP TGPSIYGTSS GGGNMTTLDF MGIGGLTPTN LHEQQHLQQR LELEAISQQR  540
LPMMNPFQQQ YSHGDSTIEK PIWDV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	8e-34	175	244	3	72	Zinc finger protein JACKDAW
5b3h_F	8e-34	175	244	3	72	Zinc finger protein JACKDAW
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Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Observed in vegetative tissues. Mainly expressed in hypocotyls, petioles, shoot apices, root tips, and trichomes, and, at low levels, in leaves, stems and flowers. {ECO:0000269\|PubMed:25035403}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016694784.1	0.0	PREDICTED: protein indeterminate-domain 2-like
Swissprot	Q9SCQ6	1e-108	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A1U8K2I5	0.0	A0A1U8K2I5_GOSHI; protein indeterminate-domain 2-like
STRING	Gorai.007G130100.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM15443	8	18

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G03840.1	2e-92	C2H2 family protein

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]